MTHFR methylation moderates the impact of smoking on DNA methylation at AHRR for African American young adults.

scientific article published on 24 April 2017

MTHFR methylation moderates the impact of smoking on DNA methylation at AHRR for African American young adults. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/AJMG.B.32544
P932PMC publication ID5561486
P698PubMed publication ID28436623

P50authorRobert A PhilibertQ58637970
Steven R H BeachQ87900416
Meeshanthini V DoganQ87900419
P2093author name stringGene H Brody
Man Kit Lei
Mei Ling Ong
P2860cites workActual Causes of Death in the United States, 2000Q22253001
A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductaseQ24324172
dbSNP: the NCBI database of genetic variationQ24608672
Hazardous compounds in tobacco smokeQ28237162
Smoking-attributable mortality, years of potential life lost, and productivity losses--United States, 2000-2004Q28300888
DNA methylation arrays as surrogate measures of cell mixture distributionQ30530775
Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smokingQ30557009
Relationship between cigarette smoking and nutrient intakes and blood status indices of older people living in the UK: further analysis of data from the National Diet and Nutrition Survey of people aged 65 years and over, 1994/95.Q30580607
A data-driven approach to preprocessing Illumina 450K methylation array dataQ30620580
Chronic cigarette smoking is associated with diminished folate status, altered folate form distribution, and increased genetic damage in the buccal mucosa of healthy adultsQ33239173
Rethinking how DNA methylation patterns are maintainedQ33763852
DNA methylation of the first exon is tightly linked to transcriptional silencingQ33803762
Tobacco-smoking-related differential DNA methylation: 27K discovery and replicationQ33860650
Characterization of six novel mutations in the methylenetetrahydrofolate reductase (MTHFR) gene in patients with homocystinuriaQ33890594
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.Q34025724
Batch effect correction for genome-wide methylation data with Illumina Infinium platformQ34101704
Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identificationQ34323060
Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibilityQ34358360
Using beta-binomial regression for high-precision differential methylation analysis in multifactor whole-genome bisulfite sequencing experimentsQ34501428
Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE reviewQ34577882
F2RL3 methylation in blood DNA is a strong predictor of mortalityQ34649151
Tobacco smoking leads to extensive genome-wide changes in DNA methylationQ34731019
Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanismsQ35190160
The Adults in the Making program: long-term protective stabilizing effects on alcohol use and substance use problems for rural African American emerging adults.Q35693461
Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokersQ35868898
Ethnicity and Smoking-Associated DNA Methylation Changes at HIV Co-Receptor GPR15Q36097654
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancyQ36379902
Demethylation of the aryl hydrocarbon receptor repressor as a biomarker for nascent smokersQ36402783
Role of the aryl hydrocarbon receptor in drug metabolismQ36572621
A Role for Epigenetics in Broadening the Scope of Pediatric Care in the Prevention of Adolescent SmokingQ37149867
One-carbon metabolism-genome interactions in folate-associated pathologiesQ37421241
Differences in smoking associated DNA methylation patterns in South Asians and EuropeansQ37559432
Meta-analysis of MTHFR gene variants in schizophrenia, bipolar disorder and unipolar depressive disorder: evidence for a common genetic vulnerability?Q37824079
Folate in smokersQ37828715
5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T and 1298A-->C mutations are associated with DNA hypomethylationQ43073677
Folic acid and prevention of spina bifida and anencephaly. 10 years after the U.S. Public Health Service recommendationQ44157676
Racial disparities in smoking-attributable mortality and years of potential life lost --- Missouri, 2003-2007Q44347093
Multivitamin supplements are inversely associated with risk of myocardial infarction in men and women--Stockholm Heart Epidemiology Program (SHEEP).Q44659174
A meta-analysis of the MTHFR C677T polymorphism and schizophrenia riskQ45281765
Ethnic and racial differences in the smoking-related risk of lung cancerQ46138958
Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes.Q51726282
Using genetically informed, randomized prevention trials to test etiological hypotheses about child and adolescent drug use and psychopathology.Q52930644
Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smokingQ57054077
Beta Regression for Modelling Rates and ProportionsQ57496575
Effect of smoking on folate levels in buccal mucosal cellsQ67556247
Cigarette smoking, intracellular vitamin deficiency, and occurrence of micronuclei in epithelial cells of the buccal mucosaQ71167295
Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylationQ73964082
The thermolabile variant 677C-->T can further reduce activity when expressed in cis with severe mutations for human methylenetetrahydrofolate reductaseQ74100085
Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase geneQ74202923
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal womenQ74739802
P433issue6
P921main subjectDNA methylationQ874745
P304page(s)608-618
P577publication date2017-04-24
P1433published inAmerican Journal of Medical Genetics Part B: Neuropsychiatric GeneticsQ15762380
P1476titleMTHFR methylation moderates the impact of smoking on DNA methylation at AHRR for African American young adults
P478volume174

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cites work (P2860)
Q89529147Cigarette and Cannabis Smoking Effects on GPR15+ Helper T Cell Levels in Peripheral Blood: Relationships with Epigenetic Biomarkers
Q92159318In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children
Q60476586Investigating the impact of cigarette smoking behaviours on DNA methylation patterns in adolescence
Q88625910MTHFR regulatory effects on methylation of CG05575921 in response to smoking: Effects are also discernable using MTHFR expression
Q89264296Maternal smoking during pregnancy and cord blood DNA methylation: new insight on sex differences and effect modification by maternal folate levels
Q60960968Methylation of Moderates the Effect of Smoking on Genomewide Methylation Among Middle Age African Americans
Q38557218Optimizing the chances of success in the search for epigenetic biomarkers: Embracing genetic variation
Q64053408Prenatal epigenetics diets play protective roles against environmental pollution
Q46354354The AhRR-c.565C>G transversion may increase total antioxidant capacity levels of the seminal plasma in infertile men.
Q57023614Using DNA methylation to validate an electronic medical record phenotype for smoking

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