Subthalamic lesion or levodopa treatment rescues giant GABAergic currents of PINK1-deficient striatum.

scientific article published in December 2012

Subthalamic lesion or levodopa treatment rescues giant GABAergic currents of PINK1-deficient striatum. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.2474-12.2012
P932PMC publication ID6621724
P698PubMed publication ID23238720
P5875ResearchGate publication ID233914358

P50authorMichael KlinkenbergQ56421702
Nathalie DehorterQ57454028
P2093author name stringGeorg Auburger
Constance Hammond
Natalia Lozovaya
Vera Tsintsadze
François J Michel
Catherine Lopez
Timur Tsintsadze
B Julius Mdzomba
Suzanna Gispert
P2860cites workDeep brain stimulation for Parkinson disease: an expert consensus and review of key issuesQ22253049
A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old miceQ27324171
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegenerationQ27348827
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient miceQ28513036
Hyperexcitable substantia nigra dopamine neurons in PINK1- and HtrA2/Omi-deficient miceQ30497725
A basal ganglia pacemaker formed by the subthalamic nucleus and external globus pallidusQ33871845
Implication of the subthalamic nucleus in the pathophysiology and pathogenesis of Parkinson's disease.Q33918872
Striatal dopamine transmission is subtly modified in human A53Tα-synuclein overexpressing miceQ34263294
The Subthalamic Nucleus becomes a Generator of Bursts in the Dopamine-Depleted State. Its High Frequency Stimulation Dramatically Weakens Transmission to the Globus PallidusQ35046511
Restriction of trophic factors and nutrients induces PARKIN expressionQ35742918
Lesion therapy for Parkinson's disease and other movement disorders: update and controversiesQ35743173
Pathological synchronization in Parkinson's disease: networks, models and treatmentsQ36833065
FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivationQ37124107
Neuro-archaeology: pre-symptomatic architecture and signature of neurological disordersQ37308350
Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significanceQ37348548
Molecular pathogenesis of Parkinson disease: insights from genetic studiesQ37561699
Microcircuitry of the direct and indirect pathways of the basal gangliaQ40829531
Evidence for a direct subthalamo-cortical loop circuit in the rat.Q42437299
Subthalamic nucleus evokes similar long lasting glutamatergic excitations in pallidal, entopeduncular and nigral neurons in the basal ganglia sliceQ42465827
Subthalamic nucleus lesion reverses motor abnormalities and striatal glutamatergic overactivity in experimental parkinsonism.Q42478271
Preservation of the direct and indirect pathways in an in vitro preparation of the mouse basal gangliaQ42492862
Distribution of spontaneous currents along the somato-dendritic axis of rat hippocampal CA1 pyramidal neurons.Q42492984
Subthalamic stimulation evokes complex EPSCs in the rat substantia nigra pars reticulata in vitroQ42493347
The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonismQ42493851
Subthalamo-pallidal interactions underlying parkinsonian neuronal oscillations in the primate basal gangliaQ42496687
Phenotypic characterisation of autosomal recessive PARK6-linked parkinsonism in three unrelated Italian familiesQ43827109
Dopamine-deprived striatal GABAergic interneurons burst and generate repetitive gigantic IPSCs in medium spiny neurons.Q45964936
Dopaminergic function in a family with the PARK6 form of autosomal recessive Parkinson's syndromeQ46399461
Mild dopaminergic lesions are accompanied by robust changes in subthalamic nucleus activityQ48200214
Mechanisms underlying altered striatal synaptic plasticity in old A53T-α synuclein overexpressing mice.Q48847188
Efferent projections of the subthalamic nucleus in the rat: light and electron microscopic analysis with the PHA-L methodQ68996730
Effect of parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulationQ72395601
Dendritic properties of hippocampal CA1 pyramidal neurons in the rat: intracellular staining in vivo and in vitroQ74278889
P433issue50
P407language of work or nameEnglishQ1860
P921main subjectlevodopaQ300989
striatumQ1319792
P304page(s)18047-18053
P577publication date2012-12-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleSubthalamic lesion or levodopa treatment rescues giant GABAergic currents of PINK1-deficient striatum
P478volume32

Reverse relations

cites work (P2860)
Q37030048Abnormal Development of Glutamatergic Synapses Afferent to Dopaminergic Neurons of the Pink1(-/-) Mouse Model of Parkinson's Disease.
Q33659576Early hypersynchrony in juvenile PINK1(-)/(-) motor cortex is rescued by antidromic stimulation
Q34046760Failure of the Nemo Trial: Bumetanide Is a Promising Agent to Treat Many Brain Disorders but Not Newborn Seizures
Q52590909GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson disease.
Q41228349Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation
Q91657533SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes

Search more.