Aberrant promoter methylation of multiple genes in oligodendrogliomas and ependymomas

scientific article

Aberrant promoter methylation of multiple genes in oligodendrogliomas and ependymomas is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0165-4608(02)00928-7
P698PubMed publication ID12850376

P2093author name stringAlberto Isla
Juan A Rey
Dolores Arjona
Jesus Lomas
M Eva Alonso
M Josefa Bello
Pilar Gonzalez-Gomez
Jose M de Campos
Jose L Sarasa
P2860cites workAllelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumorsQ71920496
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islandsQ24631957
Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomasQ24671002
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agentsQ27777800
hRAD54 gene and 1p high-resolution deletion-mapping analyses in oligodendrogliomasQ28142829
Cancer cell cyclesQ29547756
Cancer epigenetics comes of ageQ29617275
Evidence for an ependymoma tumour suppressor gene in chromosome region 22pter-22q11.2.Q30486834
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.Q33781484
Methylation and colorectal cancerQ34378429
Infrequency of p53 gene mutations in ependymomasQ34388064
Glutathione S-transferases: gene structure and regulation of expressionQ36764382
Transcriptional inactivation of TP73 expression in oligodendroglial tumorsQ38290743
CpG island methylation status and mutation analysis of the RB1 gene essential promoter region and protein-binding pocket domain in nervous system tumoursQ38302408
Changing views of the role of matrix metalloproteinases in metastasisQ41592276
Mutation analysis of the p73 gene in nonastrocytic brain tumoursQ41876841
Initiation of DNA replication at CpG islands in mammalian chromosomesQ42643271
Mutational analysis of p73 and p53 in human cancer cell linesQ47957541
Methylation and silencing of the Thrombospondin-1 promoter in human cancerQ48192580
Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomasQ48374829
Analysis of the NF2 gene in oligodendrogliomas and ependymomasQ48613043
Identification of novel regions of allelic loss in ependymomas by high-resolution allelotyping with 384 microsatellite markersQ48805667
Concurrent inactivation of RB1 and TP53 pathways in anaplastic oligodendrogliomas.Q52544855
NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas.Q53423655
Oligodendroglial tumors frequently demonstrate hypermethylation of the CDKN2A (MTS1, p16INK4a), p14ARF, and CDKN2B (MTS2, p15INK4b) tumor suppressor genes.Q55473852
Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas--implications for tumor biology and potential clinical utility.Q55474087
Concurrent hypermethylation of multiple genes is associated with grade of oligodendroglial tumors.Q55474205
Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas.Q55474435
CDKN2A/p16 inactivation in the prognosis of oligodendrogliomas.Q55474994
Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss.Q55475593
Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.Q55476212
Loss of heterozygosity for distal markers on 22q in human gliomasQ55483473
Alterations in DNA Methylation: A Fundamental Aspect of NeoplasiaQ56418625
P433issue2
P921main subjectoligodendrogliomaQ1318384
P304page(s)134-142
P577publication date2003-07-01
P1433published inCancer Genetics and CytogeneticsQ15753061
P1476titleAberrant promoter methylation of multiple genes in oligodendrogliomas and ependymomas
P478volume144

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cites work (P2860)
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Q24683906Microarray analysis of pediatric ependymoma identifies a cluster of 112 candidate genes including four transcripts at 22q12.1-q13.3
Q56673183Microarray analysis of pediatric ependymoma identifies a cluster of 112 candidate genes including four transcripts at 22q12.1-q13.3
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