DNA Methyltransferases Demonstrate Reduced Activity against Arabinosylcytosine: Implications for Epigenetic Instability in Acute Myeloid Leukemia

scientific article

DNA Methyltransferases Demonstrate Reduced Activity against Arabinosylcytosine: Implications for Epigenetic Instability in Acute Myeloid Leukemia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/ACS.BIOCHEM.7B00208
P932PMC publication ID5638661
P698PubMed publication ID28394581

P50authorRahul M. KohliQ55189769
P2093author name stringMartin Carroll
Christopher S Nabel
Jamie E DeNizio
P2860cites workInstability and decay of the primary structure of DNAQ22122361
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramersQ24339485
Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA MethylationQ27677188
Structure and function in the uracil-DNA glycosylase superfamilyQ28143922
Genomic DNA methylation: the mark and its mediatorsQ28290773
Unlocking the sugar "steric gate" of DNA polymerasesQ28303047
TET enzymes, TDG and the dynamics of DNA demethylation.Q33715010
A novel role of DNA polymerase eta in modulating cellular sensitivity to chemotherapeutic agentsQ34512077
Lethality of human myeloblasts correlates with the incorporation of arabinofuranosylcytosine into DNAQ35368280
Clonal evolution and devolution after chemotherapy in adult acute myelogenous leukemiaQ36842838
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.Q37079676
Nucleic acid determinants for selective deamination of DNA over RNA by activation-induced deaminase.Q37143544
Characterizing DNA methylation alterations from The Cancer Genome AtlasQ37410593
Chemotherapy options for previously untreated acute myeloid leukemiaQ38585930
The mechanisms of lethal action of arabinosyl cytosine (araC) and arabinosyl adenine (araA)Q39635068
High frequency mutagenesis by a DNA methyltransferaseQ41917002
Incorporation of gemcitabine and cytarabine into DNA by DNA polymerase beta and ligase III/XRCC1.Q43066632
Effect of 1-beta-D-arabinofuranosylcytosine triphosphate on DNA synthesis in isolated HeLa cell nucleiQ44269752
RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation ForwardQ58050055
Drugs five years later: cytarabineQ66843357
Instability of (ara-C) DNA under alkaline conditionsQ70676981
Relationships among Ara-CTP pools, formation of (Ara-C)DNA, and cytotoxicity of human leukemic cellsQ70945018
Comparison of cytotoxicity and antiviral activity of 1-beta-D-arabino-furanosyl-5-iodocytosine with related compoundsQ71562528
The effect of-beta-D-arabinofuranosylcytosine on growth, viability, and DNA synthesis of mouse L-cellsQ71726729
Studies in mouse L-cells on the incorporation of 1-beta-D-arabinofuranosylcytosine into DNA and on inhibition of DNA polymerase by 1-beta-D-arabinofuranosylcytosine 5'-triphosphateQ71726732
Transport and phosphorylation as factors in the antitumor action of cytosine arabinosideQ72221271
Inhibition of mammalian DNA polymerase by the 5'-triphosphate of 1-beta-d-arabinofuranosylcytosine and the 5'-triphosphate of 9-beta-d-arabinofuranoxyladenineQ72310743
The roles of DNA polymerases alpha, beta, and gamma in DNA repair synthesis induced in hamster and human cells by different DNA damaging agentsQ72673746
INHIBITION BY METABOLIC ANALOGUES OF PLAQUE FORMATION BY HERPES ZOSTER AND HERPES SIMPLEX VIRUSESQ76984816
Antitumor activity of 1-beta-D-arainofuranosylcytosine hydrochlorideQ78832284
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)2166-2169
P577publication date2017-04-12
P1433published inBiochemistryQ764876
P1476titleDNA Methyltransferases Demonstrate Reduced Activity against Arabinosylcytosine: Implications for Epigenetic Instability in Acute Myeloid Leukemia
P478volume56

Search more.