Effects of systemic resiniferatoxin treatment on substance P mRNA in rat dorsal root ganglia and substance P receptor mRNA in the spinal dorsal horn

scientific article published in January 1999

Effects of systemic resiniferatoxin treatment on substance P mRNA in rat dorsal root ganglia and substance P receptor mRNA in the spinal dorsal horn is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-8993(98)01168-8
P698PubMed publication ID9878727

P50authorTomas HökfeltQ2440397
P2093author name stringSzallasi A
Lundberg JM
Krause JE
Tucker JB
Farkas-Szallasi T
P2860cites workThe mechanism of action of capsaicin on sensory C-type neurons and their axons in vitroQ69453900
Capsaicin and its analogs induce ion channels in planar lipid bilayersQ70986664
Increased levels of GMAP, VIP and nitric oxide synthase, and their mRNAs, in lumbar dorsal root ganglia of the rat following systemic resiniferatoxin treatmentQ70986724
Intracisternal capsaicin: Selective degeneration of chemosensitive primary sensory afferents in the adult ratQ71071052
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Capsaicin-induced currents with distinct desensitization and Ca2+ dependence in rat trigeminal ganglion cellsQ71314001
Capsaicin activated currents in rat dorsal root ganglion cellsQ71676121
Multiple capsaicin-evoked currents in isolated rat sensory neuronsQ71806458
Capsaicin affects the structure and phase organization of phospholipid membranesQ72109594
Substance P biosynthesis in dorsal root ganglia: an immunochemical study of [35S]methionine and [3H]proline incorporation in vitroQ72650624
Depletion of primary afferent substance P by capsaicin and dihydrocapsaicin without altered thermal sensitivity in ratsQ72658821
Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal ratQ72687335
NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increased during adjuvant or formalin-induced nociceptionQ72756940
Suppression of bladder hyperreflexia by intravesical resiniferatoxinQ73676177
Capsaicin-induced inhibition of axoplasmic transport is prevented by nerve growth factorQ93593530
Selective degeneration by capsaicin of a subpopulation of primary sensory neurons in the adult ratQ93637718
The capsaicin receptor: a heat-activated ion channel in the pain pathwayQ24322558
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Vanilloid receptor loss in rat sensory ganglia associated with long term desensitization to resiniferatoxinQ28155908
Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepperQ28277521
Molecular characterization of a functional cDNA encoding the rat substance P receptorQ33891305
Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin AQ34594580
Resiniferatoxin and its analogs provide novel insights into the pharmacology of the vanilloid (capsaicin) receptorQ37899876
Sensory neuron-specific actions of capsaicin: mechanisms and applicationsQ37949973
Pharmacologic actions of capsaicin: Apparent involvement of substance P and serotoninQ39289088
New pharmacological strategies for pain reliefQ39469281
Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptidesQ39645839
Capsaicin-induced depletion of substance P from primary sensory neuronesQ40164536
Capsaicin and pain mechanismsQ40424034
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Urodynamic effects of intravesical resiniferatoxin in humans: preliminary results in stable and unstable detrusorQ40878055
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Capsaicin-induced neuronal degeneration: silver impregnation of cell bodies, axons, and terminals in the central nervous system of the adult rat.Q41253057
Sensitive mRNA detection using unfixed tissue: combined radioactive and non-radioactive in situ hybridization histochemistryQ41858740
The contribution of capsaicin-sensitive innervation to activation of the spinal vesico-vesical reflex in rats: relationship between substance P levels in the urinary bladder and the sensory-efferent function of capsaicin-sensitive sensory neuronsQ41950330
Systemic capsaicin in the adult rat differentially affects gene expression for neuropeptides and neurotrophin receptors in primary sensory neuronsQ42551795
Decrease of substance P in primary afferent neurones and impairment of neurogenic plasma extravasation by capsaicinQ42630933
Effects of substance P on functionally identified units in cat spinal cordQ44184726
A quantitative study of the effects of neonatal capsaicin treatment and of subsequent peripheral nerve transection in the adult rat.Q44836359
Identification of nerve growth factor-responsive sequences within the 5' region of the bovine preprotachykinin geneQ48198750
Biphasic time-course of capsaicin-induced substance P depletion: failure to correlate with thermal analgesia in the ratQ48600528
Effects of the capsaicin analogue resiniferatoxin on spinal nociceptive mechanisms in the rat: behavioral, electrophysiological and in situ hybridization studiesQ48759998
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Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranesQ48931726
The effects of capsaicin pre-treatment on the responses of single neurones to sensory stimuli in the trigeminal nucleus caudalis of the rat: Evidence against a role for substance P as the neurotransmitter serving thermal nociceptionQ48952311
Immunohistochemical studies on the effect of capsaicin on spinal and medullary peptide and monoamine neurons using antisera to substance P, gastrin/CCK, somatostatin, VIP, enkephalin, neurotensin and 5-hydroxytryptamineQ49152913
Distinct structure-activity relations for stimulation of 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes.Q52319404
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Pharmacologically induced selective degeneration of chemosensitive primary sensory neuronesQ59082877
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Effects of capsaicin on rat liver S9-mediated metabolism and DNA binding of aflatoxinQ67986424
Quantitative estimation of the effects of capsaicin on the mouse primary sensory neuronsQ69034599
Distribution of calcitonin gene-related peptide-like immunoreactivity in various rat tissues: correlation with substance P and other tachykinins and sensitivity to capsaicinQ69058558
Solution hybridization-nuclease protection assays for sensitive detection of differentially spliced substance P- and neurokinin A-encoding messenger ribonucleic acidsQ69072168
Capsaicin and its analogs inhibit the activity of NADH-coenzyme Q oxidoreductase of the mitochondrial respiratory chainQ69189528
Duration of desensitization and ultrastructural changes in dorsal root ganglia in rats treated with resiniferatoxin, an ultrapotent capsaicin analogQ69425182
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectsubstance PQ411041
P1104number of pages8
P304page(s)177-184
P577publication date1999-01-01
P1433published inBrain ResearchQ4955782
P1476titleEffects of systemic resiniferatoxin treatment on substance P mRNA in rat dorsal root ganglia and substance P receptor mRNA in the spinal dorsal horn
P478volume815

Reverse relations

cites work (P2860)
Q90394731Calcium imaging of primary canine sensory neurons: Small-diameter neurons responsive to pruritogens and algogens
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Q40702032Nerve growth factor regulates galanin and c-jun overexpression occurring in dorsal root ganglion cells after intravesical resiniferatoxin application
Q73291605Nerve growth factor stimulates synthesis of calcitonin gene-related peptide in dorsal root ganglion cells during sensory regeneration in capsaicin-treated rats
Q35753357Potential therapeutic targets for the treatment of detrusor overactivity
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Q34635423Vanilloid receptor and detrusor instability.
Q30453626Vanilloid receptors in hearing: altered cochlear sensitivity by vanilloids and expression of TRPV1 in the organ of corti

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