Synaptosomes secrete and uptake functionally active microRNAs via exocytosis and endocytosis pathways

scientific article published on 21 November 2012

Synaptosomes secrete and uptake functionally active microRNAs via exocytosis and endocytosis pathways is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/JNC.12057
P698PubMed publication ID23083096
P5875ResearchGate publication ID232527152

P2093author name stringJie Xu
Qun Chen
Ke Zen
Chenyu Zhang
Qipeng Zhang
P2860cites workHuman Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAsQ24299641
An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAPQ24645518
RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cellsQ24652266
Most mammalian mRNAs are conserved targets of microRNAsQ24655061
Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparationQ24681205
Argonaute2 is the catalytic engine of mammalian RNAiQ27860545
Oncomirs - microRNAs with a role in cancerQ27860773
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
Identification of tissue-specific microRNAs from mouseQ27860892
MicroRNAs: small RNAs with a big role in gene regulationQ27860896
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous systemQ28302231
A microRNA array reveals extensive regulation of microRNAs during brain developmentQ29618667
Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous systemQ33701894
Dicer is required for survival of differentiating neural crest cellsQ33886131
RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts.Q34003299
Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signalingQ35047447
Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology.Q35514280
Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulationQ35606143
Rapid isolation of synaptoneurosomes and postsynaptic densities from adult mouse hippocampusQ36054141
Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrainQ37013773
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampusQ37352375
microRNA regulation of synaptic plasticityQ37490887
Spatially restricting gene expression by local translation at synapsesQ37715121
microRNAs: tiny RNA molecules, huge driving forces to move the cellQ37825845
microRNAs in neurons: manifold regulatory roles at the synapseQ37874365
Horizontal transfer of microRNAs: molecular mechanisms and clinical applicationsQ37982297
Wnt1-cre-mediated conditional loss of Dicer results in malformation of the midbrain and cerebellum and failure of neural crest and dopaminergic differentiation in miceQ42660124
Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent mannerQ46644002
Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegenerationQ48112220
MicroRNA loss enhances learning and memory in miceQ48174132
Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression.Q53510675
Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease PathwaysQ57982495
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
exocytosisQ323426
P304page(s)15-25
P577publication date2012-11-21
P1433published inJournal of NeurochemistryQ6295643
P1476titleSynaptosomes secrete and uptake functionally active microRNAs via exocytosis and endocytosis pathways
P478volume124