Characterization of mitochondrial glutaminase and amino acids at prolonged times after experimental focal cerebral ischemia

scientific article published in November 1998

Characterization of mitochondrial glutaminase and amino acids at prolonged times after experimental focal cerebral ischemia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0006-8993(98)01006-3
P698PubMed publication ID9824679

P2093author name stringLo EH
Taylor L
Meng W
Newcomb R
Kano T
Curthoys N
Pierce AR
Bosque-Hamilton P
P2860cites workFocal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery OcclusionQ28281653
Metabolism and action of amino acid analog anti-cancer agentsQ28298599
In vitro characterization of the mitochondrial processing and the potential function of the 68-kDa subunit of renal glutaminaseQ28306335
Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell culturesQ34032447
Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortexQ34308086
Prolonged persistence of substantial volumes of potentially viable brain tissue after stroke: a correlative PET-CT study with voxel-based data analysisQ36797334
Neuroprotection with NBQX in rat focal cerebral ischemia. Effects on ADC probability distribution functions and diffusion-perfusion relationshipsQ36847416
Mitochondrial metabolism of glutamine and glutamate and its physiological significanceQ40089779
Regulation of glutaminase activity and glutamine metabolismQ40926056
Secondary elevation of extracellular neurotransmitter amino acids in the reperfusion phase following focal cerebral ischemiaQ42512944
Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamineQ44364283
Regional distribution and extracellular levels of amino acids in rat central nervous systemQ44420047
Distribution of phosphate-activated glutaminase, succinic dehydrogenase, pyruvate dehydrogenase and gamma-glutamyl transpeptidase in post-mortem brain from Huntington's disease and agonal casesQ45296514
Increased production of extracellular glutamate by the mitochondrial glutaminase following neuronal death.Q46308714
Glucose can fuel glutamate uptake in ischemic brain.Q46472200
Induction of 70-kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat.Q46665955
Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbitsQ46802275
Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicityQ46902644
Pharmacologic reversal of acute changes in diffusion-weighted magnetic resonance imaging in focal cerebral ischemiaQ48094718
Effects of diverse omega-conopeptides on the in vivo release of glutamic and gamma-aminobutyric acidsQ48172163
Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemiaQ48259789
Ischemia-induced accumulation of extracellular amino acids in cerebral cortex, white matter, and cerebrospinal fluidQ48365828
Time course of cerebral blood flow and histological outcome after focal cerebral ischemia in ratsQ48446751
Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitroQ48477647
Quantitative Examination of Tissue Concentration Profiles Associated with MicrodialysisQ48511176
Progressive derangement of periinfarct viable tissue in ischemic strokeQ48517661
Alterations in K+ evoked profiles of neurotransmitter and neuromodulator amino acids after focal ischemia-reperfusionQ48538111
Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemiaQ48595418
Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortexQ48941184
Swelling-induced release of glutamate, aspartate, and taurine from astrocyte culturesQ49014969
Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis?Q49108868
Vicious cycle involving Na+ channels, glutamate release, and NMDA receptors mediates delayed neurodegeneration through nitric oxide formation.Q51564479
Chronic cerebral hypoperfusion elicits neuronal apoptosis and behavioral impairment.Q52039417
Hypoxic neuronal injury in vitro depends on extracellular glutamineQ57378358
Correlation of triphenyltetrazolium chloride perfusion staining with conventional neurohistology in the detection of early brain ischaemiaQ69053302
Maximal activities of key enzymes of glutaminolysis, glycolysis, Krebs cycle and pentose-phosphate pathway of several tissues in mature and aged ratsQ69384881
The orientation of phosphate-dependent glutaminase on the inner membrane of rat renal mitochondriaQ70108526
Damage to neurons in culture following medium change: role of glutamine and extracellular generation of glutamateQ72656519
Inhibition of poly(ADP-ribose) polymerase: reduction of ischemic injury and attenuation of N-methyl-D-aspartate-induced neurotransmitter dysregulationQ74460455
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcerebral infarctionQ1209150
P304page(s)103-111
P577publication date1998-11-01
P1433published inBrain ResearchQ4955782
P1476titleCharacterization of mitochondrial glutaminase and amino acids at prolonged times after experimental focal cerebral ischemia
P478volume813

Reverse relations

cites work (P2860)
Q34611606Altered glutamatergic metabolism associated with punctate white matter lesions in preterm infants
Q36104665Astrocytic contributions to bioenergetics of cerebral ischemia
Q44578001Bacterial expression, purification, and characterization of rat kidney-type mitochondrial glutaminase
Q38472354Brain glutaminases
Q24290348Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing
Q89965768Glutaminase 1 Regulates Neuroinflammation After Cerebral Ischemia Through Enhancing Microglial Activation and Pro-Inflammatory Exosome Release
Q46644349Imaging experimental cerebral malaria in vivo: significant role of ischemic brain edema.
Q37639180Intracerebral microdialysis in children
Q22253340Isolation, characterization and expression of a human brain mitochondrial glutaminase cDNA
Q51411463Methods of Measuring Enzyme Activity Ex Vivo and In Vivo.
Q40013166Novel form of phosphate activated glutaminase in cultured astrocytes and human neuroblastoma cells, PAG in brain pathology and localization in the mitochondria
Q39253539Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)
Q35699016Potentiation of Excitotoxicity in HIV-1 Associated Dementia and the Significance of Glutaminase
Q37875876Role of glutamine in neuronal survival and death during brain ischemia and hypoglycemia

Search more.