Reduced ethanol drinking following selective cortical interneuron deletion of the GluN2B NMDA receptors subunit

scientific article published on 12 August 2016

Reduced ethanol drinking following selective cortical interneuron deletion of the GluN2B NMDA receptors subunit is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.ALCOHOL.2016.07.005
P932PMC publication ID5444088
P698PubMed publication ID28109345

P50authorNicholas J. JuryQ47705501
Anna K RadkeQ64507734
P2093author name stringKazu Nakazawa
Andrew Holmes
Eric Delpire
P2860cites workCortical GluN2B deletion attenuates punished suppression of food reward-seeking.Q40681104
GluN2B antagonism affects interneurons and leads to immediate and persistent changes in synaptic plasticity, oscillations, and behaviorQ40778694
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The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat.Q45236957
D-cycloserine facilitates extinction of conditioned alcohol-seeking behaviour in ratsQ46302123
Functional roles of NMDA receptor NR2A and NR2B subunits in the acute intoxicating effects of ethanol in miceQ46415870
The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effectQ46436811
Chronic intermittent ethanol exposure enhances NMDA-receptor-mediated synaptic responses and NMDA receptor expression in hippocampal CA1 regionQ46512300
Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum: implications for alcohol drinking behavior.Q46573395
Up-regulation of NMDA receptor subunits in rat brain following chronic ethanol treatmentQ47759859
Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression.Q47954570
Chronic ethanol exposure and withdrawal influence NMDA receptor subunit and splice variant mRNA expression in the rat cerebral cortexQ48259525
Comparison of chronic ethanol and chronic intermittent ethanol treatments on the expression of GABA(A) and NMDA receptor subunitsQ48472372
Chronic EtOH effects on putative measures of compulsive behavior in miceQ49123417
Ethanol inhibits NMDA-activated ion current in hippocampal neuronsQ56226684
Chronic ethanol treatment differentially regulates NMDA receptor subunit mRNA expression in rat brainQ72285865
Implications of the NR2B subunit-containing NMDA receptor localized in mouse limbic forebrain in ethanol dependenceQ74107184
Driving fast-spiking cells induces gamma rhythm and controls sensory responsesQ24627041
Glutamatergic targets for new alcohol medicationsQ26824012
Gamma rhythms link prefrontal interneuron dysfunction with cognitive inflexibility in Dlx5/6(+/-) mice.Q27305944
Corticostriatal circuitry and habitual ethanol seekingQ28085242
The NR2B subtype of NMDA receptor: a potential target for the treatment of alcohol dependenceQ28265181
Subregion- and cell type-restricted gene knockout in mouse brainQ28300369
Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatumQ28592654
Abnormal neural oscillations and synchrony in schizophreniaQ29619846
Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learningQ30494493
Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse.Q30496867
GluN2B in corticostriatal circuits governs choice learning and choice shifting.Q30541844
Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypesQ33556077
N-methyl-D-aspartate receptor subunit expression in adult and adolescent brain following chronic ethanol exposureQ34124379
NR2B-deficient mice are more sensitive to the locomotor stimulant and depressant effects of ethanolQ34162623
Ethanol and NMDA receptor signalingQ34186902
Chronic alcohol alters rewarded behaviors and striatal plasticityQ34253110
Chronic alcohol exposure alters behavioral and synaptic plasticity of the rodent prefrontal cortexQ34292506
Expression of glutamatergic genes in healthy humans across 16 brain regions; altered expression in the hippocampus after chronic exposure to alcohol or cocaineQ34559804
Interneurons are necessary for coordinated activity during reversal learning in orbitofrontal cortex.Q35034468
Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbensQ35110328
NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonismQ35586357
Impaired discrimination learning in interneuronal NMDAR-GluN2B mutant miceQ35655709
GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis.Q35749789
D-Serine and D-Cycloserine Reduce Compulsive Alcohol Intake in RatsQ35960341
Chronic Intermittent Ethanol Exposure Enhances the Excitability and Synaptic Plasticity of Lateral Orbitofrontal Cortex Neurons and Induces a Tolerance to the Acute Inhibitory Actions of EthanolQ36565669
Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxicationQ36922887
Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake.Q37610891
Activation of prefrontal cortical parvalbumin interneurons facilitates extinction of reward-seeking behaviorQ37617397
Two Binges of Ethanol a Day Keep the Memory Away in Adolescent Rats: Key Role for GLUN2B SubunitQ38690323
Chronic intermittent alcohol disrupts the GluN2B-associated proteome and specifically regulates group I mGlu receptor-dependent long-term depressionQ40343438
Alcohol exposure alters NMDAR function in the bed nucleus of the stria terminalisQ40368034
P304page(s)47-51
P577publication date2016-08-12
P1433published inAlcoholQ15724430
P1476titleReduced ethanol drinking following selective cortical interneuron deletion of the GluN2B NMDA receptors subunit
P478volume58

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cites work (P2860)
Q47901530Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits.
Q38725706Chronic Ethanol During Adolescence Impacts Corticolimbic Dendritic Spines and Behavior.
Q89313961NMDA receptor GluN2A subunit deletion protects against dependence-like ethanol drinking

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