Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells

scientific article published on 29 May 2017

Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1080/15569527.2017.1335748
P698PubMed publication ID28554225

P50authorChun W. MaiQ39190542
Chee-Onn LeongQ91561364
Lai Chun WongQ96226765
P2093author name stringYou Sheng Chong
P2860cites workA randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8Q24544001
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9Q24546140
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88Q24621930
Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyesQ24673347
NLRP3 inflammasome: activation and regulation in age-related macular degenerationQ26995315
Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular DegenerationQ28290149
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophyQ28590969
Age-related macular degeneration--emerging pathogenetic and therapeutic conceptsQ33263472
Why has Nature Chosen Lutein and Zeaxanthin to Protect the Retina?Q33687586
Lutein, zeaxanthin, and the macular pigmentQ33947513
Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial).Q33977885
The role of oxidative stress in the pathogenesis of age-related macular degeneration.Q34060719
Cell models to study regulation of cell transformation in pathologies of retinal pigment epitheliumQ34080190
Hydrogen peroxide in the human body.Q34099983
Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatmentQ34400646
DICER1 deficit induces Alu RNA toxicity in age-related macular degenerationQ34796058
A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseasesQ35044923
Effects of lutein or lutein in combination with vitamin C on mRNA expression and activity of antioxidant enzymes and status of the antioxidant system in SD ratsQ36149508
Functional importance of Dicer protein in the adaptive cellular response to hypoxiaQ36217312
Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT PathwayQ36255950
Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1)Q36280761
Elevated Fundus Autofluorescence in Monkeys Deficient in Lutein, Zeaxanthin, and Omega-3 Fatty AcidsQ36738021
Nutrient supplementation with n3 polyunsaturated fatty acids, lutein, and zeaxanthin decrease A2E accumulation and VEGF expression in the retinas of Ccl2/Cx3cr1-deficient mice on Crb1rd8 backgroundQ36926292
Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cellsQ37098578
Efficacy of Ethanol Extract of Fructus lycii and Its Constituents Lutein/Zeaxanthin in Protecting Retinal Pigment Epithelium Cells against Oxidative Stress: In Vivo and In Vitro Models of Age-Related Macular DegenerationQ37218617
Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cellsQ37450470
Genotoxic effects of carotenoid breakdown products in human retinal pigment epithelial cellsQ37485773
Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis.Q38238059
6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ).Q38316069
A protective effect of anthocyanins and xanthophylls on UVB-induced damage in retinal pigment epithelial cellsQ38802196
Mechanisms Underlying the Anti-Inflammatory Effects of Clinacanthus nutans Lindau Extracts: Inhibition of Cytokine Production and Toll-Like Receptor-4 ActivationQ39176750
Zeaxanthin, a retinal carotenoid, protects retinal cells against oxidative stressQ39859940
P-Glycoprotein expression in human retinal pigment epithelium cell linesQ40306271
Oxidative stress in ARPE-19 cultures: do melanosomes confer cytoprotection?Q40342011
Effect of a complex lutein formula in an animal model for light-induced retinal degenerationQ40390517
Oxidative stress, hypoxia, and autophagy in the neovascular processes of age-related macular degeneration.Q42413400
Hydrogen peroxide stimulates apoptosis in cultured human retinal pigment epithelial cellsQ43681092
Changes in macular pigment optical density and serum concentrations of its constituent carotenoids following supplemental lutein and zeaxanthin: the LUNA studyQ44212321
Hydrogen peroxide-induced cell death in a human retinal pigment epithelial cell line, ARPE-19.Q44526629
Improvement of retinal function in early age-related macular degeneration after lutein and zeaxanthin supplementation: a randomized, double-masked, placebo-controlled trialQ44696848
Toxicity of oxidized beta-carotene to cultured human cellsQ46557286
Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: the Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973.Q50268024
Lutein supplementation over a one-year period in early AMD might have a mild beneficial effect on visual acuity: the CLEAR study.Q53121765
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)52-60
P577publication date2017-05-29
P1433published inCutaneous and Ocular ToxicologyQ5196688
P1476titleLutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells
P478volume37

Reverse relations

Q91814356Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarianscites workP2860

Search more.