Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators

scientific article published in October 1998

Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators is …
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scholarly articleQ13442814

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P356DOI10.1016/S0140-6736(98)08020-9
P698PubMed publication ID9788453

P50authorPaul TrouillasQ11984910
Markku KasteQ16299732
Geoffrey A. DonnanQ38545177
P2093author name stringS Davis
C Fieschi
D Schneider
D Meier
E Bluhmki
W Hacke
V Larrue
A Davalos
R von Kummer
E Diez-Tejedor
P2860cites workTissue plasminogen activator for acute ischemic strokeQ29619377
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Hemorrhagic cerebral infarction--a prospective studyQ48371863
Stroke units versus general medical wards, I: twelve- and eighteen-month survival: a randomized, controlled trialQ48554368
Streptokinase for acute ischemic stroke with relationship to time of administration: Australian Streptokinase (ASK) Trial Study GroupQ48913792
Thrombolytic therapy with streptokinase in acute ischemic strokeQ48962264
Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)Q55063586
Hemorrhagic transformation in cerebral embolismQ69605427
Treatment of acute ischemic stroke. Challenging the concept of a rigid and universal time windowQ71568495
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Stroke unit versus general medical wards, II: neurological deficits and activities of daily living: a quasi-randomized controlled trialQ74324126
P433issue9136
P407language of work or nameEnglishQ1860
P921main subjectplaceboQ269829
thrombolysisQ1931577
placebo-controlled trialQ108853737
P304page(s)1245-1251
P577publication date1998-10-01
P1433published inThe LancetQ939416
P1476titleRandomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators
P478volume352

Reverse relations

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Q36104057Frequency and predictors of symptomatic intracranial hemorrhage after intravenous thrombolysis for acute ischemic stroke in a Brazilian public hospital.
Q64108422Frequency of Hemorrhage on Follow Up Imaging in Stroke Patients Treated With rt-PA Depending on Clinical Course
Q92595056Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial
Q73906894Glycine antagonist (gavestinel) in neuroprotection (GAIN International) in patients with acute stroke: a randomised controlled trial. GAIN International Investigators
Q44742128Graded reoxygenation with chemical inhibition of oxidative phosphorylation improves posthypoxic recovery in murine hippocampal slices
Q34170539Graphic reanalysis of the two NINDS-tPA trials confirms substantial treatment benefit
Q36561350Gray-Matter Volume Estimate Score: A Novel Semi-Automatic Method Measuring Early Ischemic Change on CT.
Q91697958Guidelines for Intravenous Thrombolysis (Recombinant Tissue-type Plasminogen Activator), the Third Edition, March 2019: A Guideline from the Japan Stroke Society
Q37640881Haemorrhagic Transformation after Ischaemic Stroke in Patients Taking Non-vitamin K Antagonist Oral Anticoagulants
Q90633783Haemorrhagic transformation following ischaemic stroke: A retrospective study
Q33249571Halving effort in acute stroke trials
Q37531421Health Aid Is Allocated Efficiently, But Not Optimally: Insights From A Review Of Cost-Effectiveness Studies
Q94456735Health Utility Weighting of the Modified Rankin Scale: A Systematic Review and Meta-analysis
Q48558753Hemiplegia and thrombolysis
Q35752364Hemorrhage Rates and Outcomes When Using up to 100 mg Intra-Arterial t-PA for Thrombolysis in Acute Ischemic Stroke
Q43505769Hemorrhagic complications after systemic thrombolysis in acute stroke patients with abnormal baseline coagulation
Q36515347Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas
Q36914630Hemorrhagic transformation: a review of the rate of hemorrhage in the major clinical trials of acute ischemic stroke
Q33842161Hemostasis and alterations of the central nervous system
Q90381934High Neutrophil-to-Lymphocyte Ratio Predicts Hemorrhagic Transformation in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis
Q92537389High Neutrophil-to-Platelet Ratio Is Associated With Hemorrhagic Transformation in Patients With Acute Ischemic Stroke
Q30671155Higher neutrophil counts before thrombolysis for cerebral ischemia predict worse outcomes.
Q36638843How temporal evolution of intracranial collaterals in acute stroke affects clinical outcomes.
Q38920992How to Measure Recovery? Revisiting Concepts and Methods for Stroke Studies
Q90472658How to Set up a Thrombectomy Service : The St. Petersburg Experience
Q45348024How to identify stroke mimics in patients eligible for intravenous thrombolysis?
Q48827756Hyperdensity on non-contrast CT immediately after intra-arterial revascularization
Q38044504IST-3: no pragmatic answers
Q36405870IV thrombolysis in very severe and severe ischemic stroke: Results from the SITS-ISTR Registry
Q42196783Identification of Reversible Disruption of the Human Blood-Brain Barrier Following Acute Ischemia
Q38051668Identifying implications of thrombolysis for stroke rehabilitation: knowledge gaps in current research.
Q40394460Identifying patients at risk of acute symptomatic seizure after ischemic stroke
Q47098542If Time Is Brain Where Is the Improvement in Prehospital Time after Stroke?
Q37679163Imaging Oxygen Metabolism In Acute Stroke Using MRI.
Q47586925Imaging assessment of acute ischaemic stroke: a review of radiological methods.
Q59858865Imaging of acute stroke
Q30831710Imaging of acute stroke prior to treatment: current practice and evolving techniques
Q36379591Imaging of cerebral ischemic edema and neuronal death.
Q30904038Imaging-based management of acute ischemic stroke patients: current neuroradiological perspectives
Q33978760Imaging-based treatment selection for intravenous and intra-arterial stroke therapies: a comprehensive review
Q47300027Impact of Anesthesia on the Outcome of Acute Ischemic Stroke after Endovascular Treatment with the Solitaire Stent Retriever.
Q33567258Impact of Baseline Ischemia on Outcome in Older Patients Undergoing Endovascular Therapy for Acute Ischemic Stroke
Q64107318Impact of Emergent Cervical Carotid Stenting in Tandem Occlusion Strokes Treated by Thrombectomy: A Review of the TITAN Collaboration
Q37052977Impact of Target Arterial Residual Stenosis on Outcome After Endovascular Revascularization
Q48592895Impact of body mass index on outcome in stroke patients treated with intravenous thrombolysis
Q49335726Impact of collateral circulation status on favorable outcomes in thrombolysis treatment: A systematic review and meta-analysis
Q35414185Impact of diffusion-weighted imaging lesion volume on the success of endovascular reperfusion therapy
Q49223257Impact of intravenous thrombolysis on length of hospital stay in cases of acute ischemic stroke
Q39570573Impact of leukoaraiosis on parenchymal hemorrhage in elderly patients treated with thrombolysis
Q35084483Impact of sex in stroke thrombolysis: a coarsened exact matching study
Q55024296Impact of smoking on stroke outcome after endovascular treatment.
Q58698188Impact of the Thrombectomy Trials on the Management and Outcome of Large Vessel Stroke: Data From the Lyon Stroke Center
Q39102006Impact of time-to-reperfusion on outcome in patients with poor collaterals.
Q85597035Implementation and outcome of thrombolysis with alteplase 3 to 4.5 h after acute stroke in Chinese patients
Q84610115Implementation and outcome of thrombolysis with alteplase 3-4.5 h after an acute stroke: an updated analysis from SITS-ISTR
Q48228152Implementation of Telemedicine and Stroke Network in thrombolytic administration: comparison between walk-in and referred patients.
Q97692853Improved collateral flow and reduced damage after remote ischemic perconditioning during distal middle cerebral artery occlusion in aged rats
Q48863199Improved outcomes in stroke thrombolysis with pre-specified imaging criteria.
Q47170593Improving Cerebral Blood Flow after Arterial Recanalization: A Novel Therapeutic Strategy in Stroke
Q37610822Improving diagnostic value of CT examinations in hyperacute ischemic stroke
Q74254446In response
Q38677213In-hospital ischaemic stroke treated with intravenous thrombolysis or mechanical thrombectomy
Q41458166Increased globulin and its association with hemorrhagic transformation in patients receiving intra-arterial thrombolysis therapy
Q39201905Infarct topography and functional outcomes.
Q47595033Influence of Renal Function on Treatment Results after Stroke Thrombectomy
Q64105269Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis
Q41481263Influence of glycaemic control on the outcomes of patients treated by intravenous thrombolysis for cerebral ischaemia
Q41293946Influence of neurologists' experience on the outcome of patients treated by intravenous thrombolysis for cerebral ischaemia
Q60597543Influence of on-going treatment with angiotensin-converting enzyme inhibitor or angiotensin receptor blocker on the outcome of patients treated with intravenous rt-PA for ischemic stroke
Q35024112Influence of racial differences on outcomes after thrombolytic therapy in acute ischemic stroke
Q92421734Initial Experience in Direct Aspiration Thrombectomy Using a Novel 0.071-Inch Aspiration Catheter
Q53250607Initial experience with a self-expanding retrievable stent for recanalization of large vessel occlusions in acute ischemic stroke.
Q48173064Initial experience with the Penumbra Stroke System for recanalization of large vessel occlusions in acute ischemic stroke
Q74654805Innovative Strategies in the Management of Acute Stroke
Q34517445Innovative strategies in the management of acute stroke
Q38860911Interhospital Transfer of Neurosurgical Patients: Implications of Timing on Hospital Course and Clinical Outcomes
Q33653013Interventional neurology: a personal road map
Q90358573Intra-Arterial Tissue Plasminogen Activator Is a Safe Rescue Therapy with Mechanical Thrombectomy
Q89395791Intra-arterial Thrombolysis in Second Trimester of Pregnancy. A Case Report
Q48969911Intra-arterial adjuvant tirofiban after unsuccessful intra-arterial thrombolysis of acute ischemic stroke: preliminary experience in 16 patients
Q43560267Intra-arterial stroke therapy: patient safety considerations
Q34261689Intra-arterial therapy as a rescue strategy after clinically failed intravenous thrombolysis may increase the likelihood of a good outcome in patients with severe ischaemic stroke. A retrospective two centre study
Q48821499Intra-arterial third-generation recombinant tissue plasminogen activator (reteplase) for acute ischemic stroke
Q48920928Intra-arterial thrombolysis in acute ischaemic stroke
Q35777379Intra-arterial thrombolysis in acute ischemic stroke: a review of pharmacologic approaches
Q45214996Intra-arterial thrombolysis in patients treated with warfarin
Q36256072Intra-arterial thrombolysis of a distal internal carotid artery occlusion in an adolescent
Q53460532Intra-arterial thrombolysis using rt-PA in patients with acute stroke due to vessel occlusion of anterior and/or posterior cerebral circulation.
Q83371509Intra-arterial thrombolysis within three hours of stroke onset in middle cerebral artery strokes
Q30470195Intra-arterial versus intra-venous thrombolysis within and after the first 3 hours of stroke onset
Q84148337Intra-arterial vs intra-venous. Thrombolysis for anterior cerebral occlusion
Q73659570Intracerebral hemorrhage
Q33184858Intracerebral hemorrhage.
Q50050498Intracranial Internal Carotid Artery Wall Calcification in Ischemic Strokes Treated with Thrombolysis.
Q89965051Intracranial Stenting After Failed Thrombectomy in Patients With Moderately Severe Stroke: A Multicenter Cohort Study
Q36302531Intracranial thrombectomy using the Solitaire stent: a historical vignette
Q47214723Intracranial thrombus extent predicts clinical outcome, final infarct size and hemorrhagic transformation in ischemic stroke: the clot burden score
Q90599551Intravenous Administration of Standard Dose Tirofiban after Mechanical Arterial Recanalization is Safe and Relatively Effective in Acute Ischemic Stroke
Q35739435Intravenous Recombinant Tissue Plasminogen Activator Does Not Impact Mortality in Acute Ischemic Stroke at Any Time Point up to 6 Months: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Q26796477Intravenous Thrombolysis for Acute Ischemic Stroke Within 3 Hours Versus Between 3 and 4.5 Hours of Symptom Onset
Q36956762Intravenous Thrombolysis for Acute Ischemic Stroke in Patients Receiving Antiplatelet Therapy: A Systematic Review and Meta-analysis of 19 Studies
Q36048610Intravenous Thrombolysis in Expanded Time Window (3-4.5 hours) in General Practice with Concurrent Availability of Endovascular Treatment.
Q42380272Intravenous Thrombolysis in Patients with Stroke Taking Rivaroxaban Using Drug Specific Plasma Levels: Experience with a Standard Operation Procedure in Clinical Practice.
Q64085121Intravenous Thrombolysis in Posterior Circulation Stroke
Q36255802Intravenous Tissue Plasminogen Activator Improves the Outcome in Very Elderly Korean Patients with Acute Ischemic Stroke
Q40065087Intravenous alteplase versus rescue endovascular procedure in patients with proximal middle cerebral artery occlusion
Q28275566Intravenous ancrod for acute ischaemic stroke in the European Stroke Treatment with Ancrod Trial: a randomised controlled trial
Q37314662Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion-diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study.
Q64905047Intravenous fibrinolysis plus endovascular thrombectomy versus direct endovascular thrombectomy for anterior circulation acute ischemic stroke: clinical and infarct volume results.
Q33785353Intravenous recombinant tissue plasminogen activator administered after 3 h following onset of ischaemic stroke: a metaanalysis
Q35490096Intravenous rt-PA for acute stroke: comparing its effectiveness in younger and older patients
Q37209014Intravenous rt-PA versus endovascular therapy for acute ischemic stroke
Q50072337Intravenous rtPA versus mechanical thrombectomy in acute ischemic stroke: A historical cohort in Joinville, Brazil
Q52150474Intravenous thrombolysis and intra-arterial interventions in acute ischemic stroke: Italian Stroke Organisation (ISO)-SPREAD guidelines.
Q38407128Intravenous thrombolysis and three-year ischemic stroke mortality
Q39034824Intravenous thrombolysis before endovascular therapy for large vessel strokes can lead to significantly higher hospital costs without improving outcomes
Q48766417Intravenous thrombolysis for acute cerebral ischaemia in old stroke patients ≥ 80 years of age.
Q37979874Intravenous thrombolysis for acute ischemic stroke in Asia
Q64326777Intravenous thrombolysis for acute ischemic stroke in Greece: the Safe Implementation of Thrombolysis in Stroke registry 15-year experience
Q34262372Intravenous thrombolysis for acute ischemic stroke patients presenting with mild symptoms
Q39394485Intravenous thrombolysis for acute ischemic stroke: a bridge between two centuries
Q36227035Intravenous thrombolysis in acute ischaemic stroke: from trial exclusion criteria to clinical contraindications. An international Delphi study
Q38225341Intravenous thrombolysis in acute ischemic stroke: standard and potential future applications
Q40134099Intravenous thrombolysis in patients aged more than 80 years in the three rural hospitals in southeast Poland: an observational study
Q64892044Intravenous thrombolysis in unwitnessed stroke onset: MR WITNESS trial results.
Q31108563Intravenous thrombolysis is more safe and effective for posterior circulation stroke: Data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China).
Q44998853Intravenous thrombolysis outcomes in patients presenting with large vessel acute ischemic strokes--CT angiography-based prognosis
Q33698627Intravenous thrombolytic therapy for stroke: a review of recent studies and controversies
Q35648096Intravenous thrombolytics for ischemic stroke
Q60221610Intérêt de la TDM de perfusion dans le diagnostic d’un AVC ischémique sylvien à la phase précoce
Q86090700In Vitro Examination of the Thrombolytic Efficacy of Desmoteplase and Therapeutic Ultrasound Compared with rt-PA
Q40531467Is acute reperfusion therapy safe in acute ischemic stroke patients who harbor unruptured intracranial aneurysm?
Q33529160Is atrial fibrillation associated with poor outcome after thrombolysis?
Q38038053Is general anaesthesia preferable to conscious sedation in the treatment of acute ischaemic stroke with intra-arterial mechanical thrombectomy? A review of the literature
Q88302804Is the Efficacy of Endovascular Treatment for Acute Ischemic Stroke Sex-Related
Q34037933Is the NIHSS certification process too lenient?
Q34566651Is the promise of randomized control trials ("evidence-based medicine") overstated?
Q57812836Ischaemic Stroke and Transient Ischaemic Attack
Q90640005Ischaemic stroke
Q34037705Ischemic penumbra: evidence from functional imaging in man.
Q37895311Ischemic stroke--novel therapeutic strategies
Q35940947Iterative Reconstruction Improves Both Objective and Subjective Image Quality in Acute Stroke CTP.
Q58599105Knowledge and Attitudes of Saudi Emergency Physicians toward t-PA Use in Stroke
Q47101474LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical simulation of symptomatic ICH.
Q37134651Lack of experience of intravenous thrombolysis for acute ischaemic stroke does not influence the proportion of patients treated
Q90698741Legal medicine implications in fibrinolytic therapy of acute ischemic stroke
Q48132154Leptin/adiponectin ratio predicts poststroke neurological outcome
Q55176428Leukoaraiosis and risk of intracranial hemorrhage and outcome after stroke thrombolysis.
Q39076189Leukoaraiosis is a predictor of futile recanalization in acute ischemic stroke.
Q35502996Leukoaraiosis on magnetic resonance imaging is related to long-term poor functional outcome after thrombolysis in acute ischemic stroke
Q33539477Limiting neurological damage after stroke: a review of pharmacological treatment options
Q46704364Lipid profile, statin use, and outcome after intravenous thrombolysis for acute ischaemic stroke.
Q39402189Locally Deliver the Tissue-Type Plasminogen Activator (tPA) Plasmid for Preventing Thrombosis
Q37041080Long-term outcomes of acute ischemic stroke in patients aged 80 years and older
Q43702546Long-term outcomes of post-thrombolytic intracerebral hemorrhage in ischemic stroke patients
Q64999053Low Cholesterol Levels Increase Symptomatic Intracranial Hemorrhage Rates After Intravenous Thrombolysis: A Multicenter Cohort Validation Study.
Q54966172Low factor XIII levels after intravenous thrombolysis predict short-term mortality in ischemic stroke patients.
Q47103883Low free triiodothyronine levels predict symptomatic intracranial hemorrhage and worse short-term outcome of thrombolysis in patients with acute ischemia stroke
Q48154216Low glomerular filtration rate increases hemorrhagic transformation in acute ischemic stroke
Q92900436Low triiodothyronine syndrome is associated with hemorrhagic transformation in patients with acute ischaemic stroke
Q37624269Low-Dose Versus Standard-Dose Tissue Plasminogen Activator in Acute Ischemic Stroke in Asian Populations: A Meta-Analysis
Q28222300Low-molecular-weight heparin compared with aspirin for the treatment of acute ischaemic stroke in Asian patients with large artery occlusive disease: a randomised study
Q31110396MR and CT perfusion imaging of the brain: principles and clinical applications
Q37317803MR mismatch profiles in patients with intracranial atherosclerotic stroke: a comprehensive approach comparing stroke subtypes
Q33922434MR perfusion imaging in acute ischemic stroke.
Q62779438MRI patient selection for endovascular thrombectomy in acute ischemic stroke: correlation between pretreatment diffusion weighted imaging and outcome scores
Q90100116MRI-based thrombolytic therapy in patients with acute ischemic stroke presenting with a low NIHSS
Q34132045MRI-guided selection of patients for treatment of acute ischemic stroke.
Q35696214MRI-guided therapy in acute stroke
Q34357599Magnetic resonance imaging in acute ischemic stroke treatment
Q24239967Magnetic resonance imaging versus computed tomography for detection of acute vascular lesions in patients presenting with stroke symptoms
Q30411823Magnetic resonance-guided focused ultrasound surgery: Part 2: A review of current and future applications
Q26796470Management of Postthrombolysis Hemorrhagic and Orolingual Angioedema Complications
Q38763038Management of acute ischaemic stroke in patients with dementia
Q34370469Management of acute ischaemic stroke in the elderly: tolerability of thrombolytics
Q33949713Management of acute ischemic stroke. What is the role of tPA and antithrombotic agents?
Q30431467Management of ischaemic stroke in the acute setting: review of the current status
Q57183611Management of patients with stroke treated with direct oral anticoagulants
Q84959671Mean platelet volume predicting carotid atherosclerosis in atherothrombotic ischemic stroke
Q36310421Mechanical Recanalization following i.v. Thrombolysis: A Retrospective Analysis regarding Secondary Hemorrhagic Infarctions and Parenchymal Hematomas
Q53058924Mechanical Thrombectomy in Acute Occlusion of the Carotid-T: A Retrospective Single Centre Study in 51 Patients.
Q55449290Mechanical Thrombectomy in Strokes with Large-Vessel Occlusion Beyond 6 Hours: A Pooled Analysis of Randomized Trials.
Q40350754Mechanical Thrombectomy of Distal Occlusions in the Anterior Cerebral Artery: Recanalization Rates, Periprocedural Complications, and Clinical Outcome.
Q33223665Mechanical recanalization for acute ischemic stroke
Q43232072Mechanical recanalization in ischemic anterior circulation stroke within an 8-hour time window: a real-world experience
Q41257786Mechanical thrombectomy for acute ischemic stroke : current evidence and open questions
Q37732255Mechanical thrombectomy for the treatment of acute ischemic stroke
Q35610113Medical management of patients with an acute stroke: treatment and prevention
Q34187207Medical management of stroke
Q34271952Medical therapy for acute ischemic stroke
Q34522800Merci Retriever in acute stroke treatment
Q37269853Methodology of acute trials in stroke
Q40060158Methods and processes for the reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial
Q39982266Midterm clinical and angiographic follow-up for the first Food and Drug Administration-approved prospective, Single-Arm Trial of Primary Stenting for Stroke: SARIS (Stent-Assisted Recanalization for Acute Ischemic Stroke).
Q34683816Migraine and functional outcome from ischemic cerebral events in women
Q38837575Minor Stroke Syndromes in Large-Vessel Occlusions: Mechanical Thrombectomy or Thrombolysis Only?
Q37005689Mismatch of Low Perfusion and High Permeability Predicts Hemorrhagic Transformation Region in Acute Ischemic Stroke Patients Treated with Intra-arterial Thrombolysis
Q97425313Missing outcome data management in acute stroke trials testing iv thrombolytics. Is there risk of bias?
Q34538611Mobilization after thrombolysis (rtPA) within 24 hours of acute stroke: what factors influence inclusion of patients in A Very Early Rehabilitation Trial (AVERT)?
Q30497328Modeling Disease Progression in Acute Stroke Using Clinical Assessment Scales
Q37711254Modeling stroke management: a qualitative review of cost-effectiveness analyses
Q36297789Modified ASPECTS for DWI including deep white matter lesions predicts subsequent intracranial hemorrhage
Q47303075Monocyte count at onset predicts poststroke outcomes during a 90-day follow-up.
Q50091286Mortality and Disability According to Baseline Blood Pressure in Acute Ischemic Stroke Patients Treated by Thrombectomy: A Collaborative Pooled Analysis.
Q57895497Mortality in patients treated by intra-venous thrombolysis for ischaemic stroke
Q88720812Multisociety Consensus Quality Improvement Revised Consensus Statement for Endovascular Therapy of Acute Ischemic Stroke
Q38103827Multisociety consensus quality improvement guidelines for intraarterial catheter-directed treatment of acute ischemic stroke, from the American Society of Neuroradiology, Canadian Interventional Radiology Association, Cardiovascular and Intervention
Q92955595Neurocognitive and functional impairment in adult and paediatric tuberculous meningitis
Q81351763Neuroimaging in acute stroke
Q30810278Neuroimaging, the ischaemic penumbra, and selection of patients for acute stroke therapy
Q33673824Neurologic complications in the intensive care unit
Q40123556Neuroprotection and the ischemic cascade
Q44318931Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: dose dependency, therapeutic time window and long-term efficacy
Q38152663Neurothrombectomy in the treatment of acute ischaemic stroke
Q36331049New goals in ischemic stroke therapy: the experimental approach--harmonizing science with practice.
Q34566330New insights on thrombolytic treatment of acute ischemic stroke
Q37673214Non-steroidal anti-inflammatory drug use and functional outcome from ischemic cerebral events among women
Q37579315Not only the Sugar, Early infarct sign, hyperDense middle cerebral artery, Age, Neurologic deficit score but also atrial fibrillation is predictive for symptomatic intracranial hemorrhage after intravenous recombinant tissue plasminogen activator
Q49689017Novel Telestroke Program Improves Thrombolysis for Acute Stroke Across 21 Hospitals of an Integrated Healthcare System
Q37207243Novel thrombolytic drugs: will they make a difference in the treatment of ischaemic stroke?
Q48068167One-year MR angiographic and clinical follow-up after intracranial mechanical thrombectomy using a stent retriever device.
Q37348177Onset of Orolingual Angioedema After Treatment of Acute Brain Ischemia with Alteplase Depends on the Site of Brain Ischemia: A Meta-analysis
Q38006071Optimal dose for stroke thrombolysis in Asians: low dose may have similar safety and efficacy as standard dose
Q34595105Optimal timing of thrombolytic therapy in acute ischaemic stroke
Q34056969Optimizing prediction scores for poor outcome after intra-arterial therapy in anterior circulation acute ischemic stroke
Q38019575Optimizing the management of acute ischaemic stroke: a review of the utilization of intravenous recombinant tissue plasminogen activator (tPA).
Q44636590Organizational changes aiming to reduce iv tPA door-to-needle time
Q36375658Outcome after systemic thrombolysis is predicted by age and stroke severity: an open label experience with recombinant tissue plasminogen activator and tirofiban
Q34326883Outcome of ischemic stroke patients with serious post-thrombolysis neurological deficits
Q57895512Outcome of patients with atrial fibrillation after intravenous thrombolysis for cerebral ischaemia
Q33719200Outcome of stroke patients receiving different doses of recombinant tissue plasminogen activator
Q38285447Outcomes after stroke thrombolysis according to prior antiplatelet use.
Q24646395Outcomes of intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 90 years or older
Q36570639Outcomes of patients with large middle cerebral artery infarct treated with and without intravenous thrombolysis
Q38489211Outcomes of stent retriever thrombectomy in basilar artery occlusion: an observational study and systematic review
Q35104807Oxfordshire Community Stroke Project classification improves prediction of post-thrombolysis symptomatic intracerebral hemorrhage
Q37083630Past, present and future of alteplase for acute ischemic stroke.
Q34574766Pathophysiology of acute middle cerebral artery infarct by multimodal computed tomography: A pilot study in Thai patients
Q36496980Pathophysiology of ischaemic stroke: insights from imaging, and implications for therapy and drug discovery.
Q59136921Patients With Ischemic Core ≥70 ml Within 6 h of Symptom Onset May Still Benefit From Endovascular Treatment
Q37133844Patients with acute stroke treated with intravenous tPA 3-6 hours after stroke onset: correlations between MR angiography findings and perfusion- and diffusion-weighted imaging in the DEFUSE study.
Q34107379Patients with acute stroke: recent developments in neuroimaging
Q45809829Penumbra system: a novel mechanical thrombectomy device for large-vessel occlusions in acute stroke.
Q43513962Penumbral probability thresholds of cortical flumazenil binding and blood flow predicting tissue outcome in patients with cerebral ischaemia
Q84639111Percutaneous Balloon Angioplasty for Acute Occlusion of Intracranial Arteries
Q83506331Percutaneous transluminal angioplasty and stent placement in acute vessel occlusion: evaluation of new methods for interventional stroke treatment
Q48146426Perfusion CT in acute stroke: prediction of vessel recanalization and clinical outcome in intravenous thrombolytic therapy
Q35113503Perfusion CT: a worthwhile enhancement?
Q53210064Perfusion-CT guided intravenous thrombolysis in patients with unknown-onset stroke: a randomized, double-blind, placebo-controlled, pilot feasibility trial.
Q60483545Perfusion-Weighted MRI in Human Acute Ischemic Stroke
Q55096016Periprocedural Antithrombotic Treatment During Acute Mechanical Thrombectomy for Ischemic Stroke: A Systematic Review.
Q30652275Periprocedural aspects in mechanical recanalization for acute stroke: data from the ENDOSTROKE registry
Q35608208Pharmaceutical sponsorship bias influences thrombolytic literature in acute ischemic stroke
Q38610670Pharmacokinetic and metabolomic analyses of the neuroprotective effects of salvianolic acid A in a rat ischemic stroke model
Q37024492Pharmacological approaches to acute ischaemic stroke: reperfusion certainly, neuroprotection possibly
Q36662909Pharmacotherapy considerations in advanced cardiac life support
Q37514167Pharmacotherapy of cerebral ischemia
Q35660646Physiologic imaging in acute stroke: Patient selection.
Q35676660Placebo and the Helsinki Declaration--what to do?
Q37998537Plasminogen activation and thrombolysis for ischemic stroke
Q36988667Plasminogen activators and ischemic stroke: conditions for acute delivery
Q93003738Post-Stroke Blood-Brain Barrier Disruption and Poor Functional Outcome in Patients Receiving Thrombolytic Therapy
Q90400706Post-hoc Analysis of Outcome of Intravenous Thrombolysis in Infarcts of Infratentorial Localization in the WAKE-UP Trial
Q47713661Post-thrombolytic blood pressure and symptomatic intracerebral hemorrhage.
Q88141734Posterior Circulation Occlusions May Be Associated with Distal Emboli During Thrombectomy : Factors for Distal Embolization and a Review of the Literature
Q41449671Posterior vs. anterior circulation infarction: demography, outcomes, and frequency of hemorrhage after thrombolysis.
Q47711814Poststroke infections are an independent risk factor for poor functional outcome after three-months in thrombolysed stroke patients
Q36130124Postthrombolytic Antiplatelet Use for Patients with Intercerebral Hemorrhage without Extensive Parenchymal Involvement Does Not Worsen Outcome
Q39447215Potential biomarkers for predicting hemorrhagic transformation of ischemic stroke
Q34061211Potential future clinical applications for the GPIIb/IIIa antagonist, abciximab in thrombosis, vascular and oncological indications
Q73740291Potential role of abciximab in ischemic cerebrovascular disease
Q31145197Power of an Adaptive Trial Design for Endovascular Stroke Studies: Simulations Using IMS (Interventional Management of Stroke) III Data.
Q38639109Predicted impact of intravenous thrombolysis on prognosis of general population of stroke patients: simulation model
Q26830834Predicting a post-thrombolysis intracerebral hemorrhage: a systematic review
Q34722493Predicting intracerebral hemorrhage by baseline magnetic resonance imaging in stroke patients undergoing systemic thrombolysis
Q41702122Predicting risk of symptomatic intracerebral hemorrhage and mortality after treatment with recombinant tissue-plasminogen activator using SEDAN score
Q47808481Predicting spontaneous early neurological recovery after acute ischemic stroke.
Q43829243Prediction of hemorrhagic transformation in acute ischaemic stroke by micro- and macroalbuminuria after intravenous thrombolysis
Q33709879Prediction of two month modified Rankin Scale with an ordinal prediction model in patients with aneurysmal subarachnoid haemorrhage
Q48136162Predictive value of flat-panel CT for haemorrhagic transformations in patients with acute stroke treated with thrombectomy.
Q64951255Predictors of Intracerebral Hemorrhage in Acute Stroke Patients Receiving Intravenous Recombinant Tissue Plasminogen Activator.
Q90680781Predictors of Outcome After Endovascular Thrombectomy in Acute Basilar Artery Occlusion and the 6hr Time Window to Recanalization
Q35862442Predictors of Outcome and Hemorrhage in Patients Undergoing Endovascular Therapy with Solitaire Stent for Acute Ischemic Stroke
Q37683678Predictors of Outcome following Stroke due to Isolated M2 Occlusions
Q52999162Predictors of a Good Outcome after Endovascular Stroke Treatment with Stent Retrievers.
Q33624072Predictors of good clinical outcome in acute stroke patients treated with intravenous thrombolysis
Q44388212Predictors of hemorrhage following intra-arterial thrombolysis for acute ischemic stroke: the role of pial collateral formation
Q51737433Preliminary study of time maximum intensity projection computed tomography imaging for the detection of early ischemic change in patient with acute ischemic stroke.
Q88047087Presence of multi-segment clot sign on dynamic CT angiography: a predictive imaging marker of recanalisation and good outcome in acute ischaemic stroke patients
Q35848283Prestroke dementia is associated with poor outcomes after reperfusion therapy among elderly stroke patients.
Q34171137Pretreatment diffusion- and perfusion-MR lesion volumes have a crucial influence on clinical response to stroke thrombolysis
Q89864495Prevalence of a Multiple Territory Stroke Pattern After Intravenous Thrombolysis
Q57826355Prevalence of disabling spasticity 1 year after first-ever stroke
Q37738247Primary intracranial stenting in acute ischemic stroke
Q90115520Professional guideline versus product label selection for treatment with IV thrombolysis: An analysis from SITS registry
Q58127014Prognostic Significance of Pulse Pressure Variability During Mechanical Thrombectomy in Acute Ischemic Stroke Patients
Q48215223Prognostic significance of proteinuria in stroke patients treated with intravenous thrombolysis.
Q93073777Prognostic value of subclinical thyroid dysfunction in ischemic stroke patients treated with intravenous thrombolysis
Q45005569Prolonged low-dose thrombolysis in posterior circulation stroke
Q34826078Quantification of errors in ordinal outcome scales using shannon entropy: effect on sample size calculations
Q100415962Quantified ischemic core's radiological hypodensity and risk of parenchymal hematoma in > 4.5 h-window stroke thrombectomy
Q35013712RAPID automated patient selection for reperfusion therapy: a pooled analysis of the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) and the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) Study
Q81098199Randomized comparison of intra-arterial and intravenous thrombolysis in a canine model of acute basilar artery thrombosis
Q53288461Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics.
Q44135056Rates and outcomes of neurosurgical treatment for postthrombolytic intracerebral hemorrhage in patients with acute ischemic stroke
Q93188834Real-World Thrombectomy Using the Sofia Catheter
Q33886064Reasons and evolution of non-thrombolysis in acute ischaemic stroke.
Q64977754Reasons for delayed admission after stroke: results of a qualitative and quantitative survey.
Q30479878Recanalization Therapies in Acute Ischemic Stroke: Pharmacological Agents, Devices, and Combinations
Q37812281Recanalization therapy for acute ischemic stroke, part 1: surgical embolectomy and chemical thrombolysis
Q64984610Recanalization treatments in basilar artery occlusion-Systematic analysis.
Q37844469Recent advances in magnetic resonance imaging in posterior circulation stroke: implications for diagnosis and prognosis
Q30626736Recent advances in the diagnosis and treatment of stroke
Q24595703Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis
Q48492153Recombinant tissue plasminogen activator increases blood-brain barrier disruption in acute ischemic stroke: an MR imaging permeability study
Q35019813Recombinant tissue-type plasminogen activator plus eptifibatide versus recombinant tissue-type plasminogen activator alone in acute ischemic stroke: propensity score-matched post hoc analysis
Q31153077Recommendations and treatment strategies for the management of acute ischemic stroke.
Q43725353Reduced risk of poststroke pneumonia in thrombolyzed stroke patients with continued statin treatment
Q36831052Reducing haemorrhagic transformation after thrombolysis for stroke: a strategy utilising minocycline
Q48854658Reducing hemorrhagic complication by dabigatran via neurovascular protection after recanalization with tissue plasminogen activator in ischemic stroke of rat.
Q48793652Referral and care for acute ischemic stroke in a Japanese tertiary emergency hospital
Q47178043Regional Differences in Thrombectomy Rates : Secondary use of Billing Codes in the MIRACUM (Medical Informatics for Research and Care in University Medicine) Consortium.
Q57173837Related Research and Recent Progress of Ischemic Penumbra
Q36289929Relation between reperfusion and hemorrhagic transformation in acute ischemic stroke
Q51065952Relationship between hospital volume and early outcomes in acute ischemic stroke patients treated with recombinant tissue plasminogen activator.
Q38950763Relationship of functional disability after a recent stroke with recurrent stroke risk
Q34038281Relationship of neurovascular elements to neuron injury during ischemia
Q35554576Reperfusion of very low cerebral blood volume lesion predicts parenchymal hematoma after endovascular therapy.
Q37898340Reperfusion strategies for acute ischemic stroke
Q90157955Reperfusion therapy for minor stroke: A systematic review and meta-analysis
Q47861990Reperfusion therapy in acute ischemic stroke: dawn of a new era?
Q37476191Reperfusion-associated hemorrhagic transformation in SHR rats: evidence of symptomatic parenchymal hematoma
Q52996663Results of multivariable logistic regression, propensity matching, propensity adjustment, and propensity-based weighting under conditions of nonuniform effect.
Q37776325Reversibility of Ischemia Evaluated by Ischemic Duration and Residual Cerebral Blood Flow
Q30248290Review article: Why is there still a debate regarding the safety and efficacy of intravenous thrombolysis in the management of presumed acute ischaemic stroke? A systematic review and meta-analysis
Q31108632Review of the current status of intra-arterial thrombolysis for treating acute cerebral infarction: a retrospective analysis of the data from multiple centers in Korea
Q55442475Review: Clinical application of diffusion tensor imaging.
Q48872792Rightward bias in right hemisphere infarct patients with or without thrombolytic treatment and in healthy controls
Q89620583Risk Factors for Epilepsy After Thrombolysis for Ischemic Stroke: A Cohort Study
Q22306325Risk Factors for Intracranial Hemorrhage in Acute Ischemic Stroke Patients Treated With Recombinant Tissue Plasminogen Activator: A Systematic Review and Meta-Analysis of 55 Studies
Q38726835Risk of Intracranial Hemorrhage after Endovascular Treatment for Acute Ischemic Stroke: Systematic Review and Meta-Analysis
Q31107456Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis
Q37274254Risk of symptomatic intracerebral hemorrhage in patients treated with intra-arterial thrombolysis
Q34948774Risks and benefits of early antithrombotic therapy after thrombolytic treatment in patients with acute stroke
Q37977532Risks and benefits of thrombolysis in the elderly
Q37850893Role of tissue plasminogen activator in acute ischemic stroke
Q44792514Routine serum C-reactive protein and stroke outcome after intravenous thrombolysis.
Q35472072S100B as a surrogate marker for successful clot lysis in hyperacute middle cerebral artery occlusion
Q46360147SOLITAIRE™ with the intention for thrombectomy (SWIFT) trial: design of a randomized, controlled, multicenter study comparing the SOLITAIRE™ Flow Restoration device and the MERCI Retriever in acute ischaemic stroke
Q44197349Safe implementation of thrombolysis in stroke-monitoring study in Italy.
Q39648908Safety and Effectiveness of Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator in 80 Years and Older Acute Ischemic Stroke Patients
Q37202149Safety and efficacy of alteplase in the treatment of acute ischemic stroke
Q34669641Safety and efficacy of desmoteplase given 3-9 h after ischaemic stroke in patients with occlusion or high-grade stenosis in major cerebral arteries (DIAS-3): a double-blind, randomised, placebo-controlled phase 3 trial
Q46226330Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial.
Q38075828Safety and efficacy of thrombolysis with intravenous alteplase in older stroke patients
Q50702011Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial.
Q41344390Safety of intravenous thrombolysis for acute ischaemic stroke including concomitant neoplastic disease sufferers - experience from Poland
Q48277692Safety of intravenous thrombolysis for acute ischemic stroke in patients with preexisting intracranial neoplasms: a case series
Q47107691Safety of thrombolysis in stroke mimics: an observational cohort study from an urban teaching hospital in Sweden.
Q64232702Safety of tirofiban and dual antiplatelet therapy in treating intracranial aneurysms
Q35802651Safety of tirofiban for patients with acute ischemic stroke in routine clinical practice
Q34538232Selection for delayed intravenous alteplase treatment based on a prognostic score
Q59812734Serum lipid level is not associated with symptomatic intracerebral hemorrhage after intravenous thrombolysis for acute ischemic stroke
Q41353520Serum osteopontin levels are upregulated and predict disability after an ischaemic stroke
Q39061399Severe cerebral hypovolemia on perfusion CT and lower body weight are associated with parenchymal haemorrhage after thrombolysis.
Q73959725Severe intracranial hemorrhage after emergency carotid stenting and abciximab administration for postoperative thrombosis
Q38302755Should minor stroke patients be thrombolyzed? A focused review and future directions.
Q42093118Should physicians give tPA to patients with acute ischemic stroke? Against: and just what is the emperor of stroke wearing?
Q83816438Should the Window for Intravenous Administration of Tissue Plasminogen Activator in the Treatment of Acute Ischemic Stroke be Extended to 4.5 Hours?
Q50439631Significance of Development and Reversion of Collaterals on MRI in Early Neurologic Improvement and Long-Term Functional Outcome after Intravenous Thrombolysis for Ischemic Stroke
Q83255927Skepticism about thrombolytics in stroke is not unreasonable
Q61649814Snake venom, vampire bat saliva, or rt-PA: time matters
Q44131035Solitaire Flow Restoration thrombectomy for acute ischemic stroke: retrospective multicenter analysis of early postmarket experience after FDA approval
Q36654730Spontaneous Splenic Rupture Following Intravenous Thrombolysis with Alteplase Applied as Stroke Therapy - Case Report and Review of Literature
Q87173838Stability of ischemic core volume during the initial hours of acute large vessel ischemic stroke in a subgroup of mechanically revascularized patients
Q46106913Statement of ESMINT and ESNR regarding recent trials evaluating the endovascular treatment at the acute stage of ischemic stroke.
Q49151358Statin pretreatment may increase the risk of symptomatic intracranial haemorrhage in thrombolysis for ischemic stroke: results from a case-control study and a meta-analysis
Q39393871Status of endovascular interventions to treat acute ischemic stroke
Q92542471Stent Retriever Thrombectomy Potentially Increases the Recanalization Rate, Improves Clinical Outcome, and Decreases Mortality in Acute Basilar Occlusion: A Systematic Review and Meta-Analysis
Q41564022Stent Retriever Thrombectomy of Small Caliber Intracranial Vessels Using pREset LITE: Safety and Efficacy
Q44579507Stent retrievers in acute ischemic stroke: complications and failures during the perioperative period.
Q38809990Stent-Retriever Thrombectomy for Acute Anterior Ischemic Stroke with Tandem Occlusion: A Systematic Review and Meta-Analysis.
Q38951472Stop Stroke: A Brief Report on Door-to-Needle Times and Performance After Implementing an Acute Care Coordination Medical Application and Implications to Emergency Medical Services
Q38117170Strategies to improve recovery in acute ischemic stroke patients: Iberoamerican Stroke Group Consensus
Q36659436Stroke Prognostication using Age and NIH Stroke Scale: SPAN-100
Q47810106Stroke attributable to acute basilar occlusion.
Q42370120Stroke mimic: Perfusion magnetic resonance imaging of a patient with ictal paralysis
Q37098053Stroke pathophysiology: management challenges and new treatment advances.
Q42270352Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. Validation using [14C]2-deoxyglucose autoradiography.
Q30151101Stroke preparedness in children: translating knowledge into behavioral intent: a systematic review and meta-analysis.
Q34037169Stroke thrombolysis: is tissue plasminogen activator a defibrillator for the brain?
Q48426796Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial
Q28166505Stroke, dementia, and drug delivery
Q51160184Stroke- on- Awakening: Safety of CT-CTA Based Selection for Reperfusion Therapy.
Q43102060Successful outcome after endovascular thrombolysis for acute ischemic stroke even after 24 h of symptoms onset?
Q36134874Successful recanalization post endovascular therapy is associated with a decreased risk of intracranial haemorrhage: a retrospective study
Q34439225Successful use of Alteplase during cardiopulmonary resuscitation following massive PE in a patient presenting with ischaemic stroke and haemorrhagic transformation.
Q40110062Surgical embolectomy for large vessel occlusion of anterior circulation
Q48140724Susceptibility Vessel Sign on MRI Predicts Favorable Clinical Outcome in Patients with Anterior Circulation Acute Stroke Treated with Mechanical Thrombectomy.
Q36118307Symptomatic intracerebral hemorrhage in acute ischemic stroke after thrombolysis with intravenous recombinant tissue plasminogen activator: a review of natural history and treatment
Q53674730Symptomatic intracranial haemorrhage after thrombolysis with adjuvant anticoagulation in basilar artery occlusion.
Q34241228Symptomatic intracranial hemorrhage after stroke thrombolysis: the SEDAN score
Q89357288Symptomatic periprocedural intracranial hemorrhage unrelated to coil embolization in 1287 patients with intracranial aneurysms
Q39425519Symptomatic post-thrombolytic intracerebral hemorrhage is not related to the cause of stroke.
Q36986430Systemic reperfusion therapy in acute ischemic stroke.
Q47880979Systolic Blood Pressure Variability is Associated with Severe Hemorrhagic Transformation in the Early Stage After Thrombolysis
Q42634449TESPI (Thrombolysis in Elderly Stroke Patients in Italy): a randomized controlled trial of alteplase (rt-PA) versus standard treatment in acute ischaemic stroke in patients aged more than 80 years where thrombolysis is initiated within three hours a
Q48785641TOAST criteria applied in acute ischemic stroke
Q46891457TPA use for stroke in the Registry of the Canadian Stroke Network.
Q40572133TURN Score Predicts 24-Hour Cerebral Edema After IV Thrombolysis.
Q40880627TURN Score Predicts 90-day Outcome in Acute Ischemic Stroke Patients After IV Thrombolysis.
Q41079114TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis.
Q91667637Technical and Clinical Outcomes After Thrombectomy for the Various Segments of the Middle Cerebral Artery
Q55008330Tenecteplase versus Alteplase for the Management of Acute Ischemic Stroke in a Low-income Country-Nepal: Cost, Efficacy, and Safety.
Q30277030Tenecteplase versus alteplase in stroke thrombolysis: An individual patient data meta-analysis of randomized controlled trials
Q48436630Texture analysis of computed tomography images of acute ischemic stroke patients
Q37599917The Alberta Stroke Program Early CT Score in clinical practice: what have we learned?
Q35055490The Albumin in Acute Stroke Part 1 Trial: an exploratory efficacy analysis
Q37057182The Basilar Artery International Cooperation Study (BASICS): study protocol for a randomised controlled trial
Q42279127The Chinese Stroke Association scientific statement: intravenous thrombolysis in acute ischaemic stroke
Q35627094The Comparison of Outcome between Thromboaspiration and Aggressive Mechanical Clot Disruption in Treating Hyperacute Stroke Patients
Q40642515The Effect of External Ventricular Drain Use in Intracerebral Hemorrhage
Q47191663The Impact of Discrepancy between Measured versus Stated Weight on Hemorrhagic Transformation and Clinical Outcomes after Intravenous Alteplase Thrombolysis
Q89536709The Impact of Loading Dose on Outcome in Stroke Patients Receiving Low-Dose Tissue Plasminogen Activator Thrombolytic Therapy
Q52599324The Influence of Sex in Stroke Thrombolysis: A Systematic Review and Meta-Analysis.
Q39063099The Italian Registry of Endovascular Treatment in Acute Stroke: rationale, design and baseline features of patients.
Q51049722The Merci Retrieval System for acute stroke: the Southeast Regional Stroke Center experience.
Q94028792The Potential Impact of Maintaining a 3-Hour IV Thrombolysis Window: How Many More Patients can we Safely Treat?
Q92275626The Risk of Symptomatic Intracranial Hemorrhage after Thrombolysis for Acute Stroke: Current Concepts and Perspectives
Q94602841The Safety and Efficiency of Tirofiban in Acute Ischemic Stroke Patients Treated with Mechanical Thrombectomy: A Multicenter Retrospective Cohort Study
Q35209739The THRIVE score predicts symptomatic intracerebral hemorrhage after intravenous tPA administration in SITS-MOST.
Q35848802The ThRombolysis in UnconTrolled Hypertension (TRUTH) protocol: an observational study on treatment strategy of elevated blood pressure in stroke patients eligible for IVT
Q38416663The Virtual International Stroke Trials Archive (VISTA): results and impact on future stroke trials and management of stroke patients
Q48321926The anti-inflammatory effect of paeoniflorin on cerebral infarction induced by ischemia-reperfusion injury in Sprague-Dawley rats
Q35786086The argatroban and tissue-type plasminogen activator stroke study: final results of a pilot safety study.
Q89547256The association between monocyte to high-density lipoprotein ratio and hemorrhagic transformation in patients with acute ischemic stroke
Q40058955The basilar artery international cooperation study (BASICS).
Q97531248The clinical conundrum of managing ischemic stroke in patients with immune thrombocytopenia
Q47683094The development of stroke services: entering the new millennium
Q51012339The effect of thrombolysis on short-term improvement depends on initial stroke severity.
Q48783061The effectiveness of thrombolysis with intravenous alteplase for acute ischemic stroke in daily practice
Q48224063The efficacy of thrombolysis in lacunar stroke - evidence from the Austrian Stroke Unit Registry
Q33566798The evolution of transcranial laser therapy for acute ischemic stroke, including a pooled analysis of NEST-1 and NEST-2
Q33716599The golden hour of acute ischemic stroke
Q34075316The impact of early specialist management on outcomes of patients with in-hospital stroke
Q37696584The neurovascular unit in the setting of stroke
Q34635173The outcome of patients with mild stroke improves after treatment with systemic thrombolysis
Q35476867The probability of middle cerebral artery MRA flow signal abnormality with quantified CT ischaemic change: targets for future therapeutic studies
Q45939202The proposed 'concordance-statistic for benefit' provided a useful metric when modeling heterogeneous treatment effects.
Q37017597The quest for arterial recanalization in acute ischemic stroke-the past, present and the future.
Q48254861The relationship between stroke severity and prior direct oral anticoagulant therapy in patients with acute ischaemic stroke and non-valvular atrial fibrillation
Q33853254The risk of intravenous thrombolysis-induced intracranial hemorrhage in Taiwanese patients with unruptured intracranial aneurysm.
Q36412737The role of additional computed tomography in the decision-making process on the secondary prevention in patients after systemic cerebral thrombolysis
Q40839819The role of perfusion CT in identifying stroke mimics in the emergency room: a case of status epilepticus presenting with perfusion CT alterations
Q35943820The safety and effectiveness of low-dose recombinant tissue plasminogen activator (0.6 mg/kg) therapy for elderly acute ischemic stroke patients (≥ 80 years old) in the pre-endovascular era
Q37554499The safety and usefulness of low molecular weight heparins and unfractionated heparins in patients with acute stroke
Q48840325The serum ferritin level is an important predictor of hemorrhagic transformation in acute ischaemic stroke
Q39985481The smoking paradox: impact of smoking on recanalization in the setting of intra-arterial thrombolysis
Q47737649The use of PWI and DWI measures in the design of "proof-of-concept" stroke trials
Q30749058The very acute stroke treatment: fibrinolysis and after
Q30499139Therapeutic advances in interventional neurology
Q30938168Therapeutic time window of thrombolytic therapy following stroke
Q38764867Therapies for Hemorrhagic Transformation in Acute Ischemic Stroke
Q64227938Therapy for acute basilar artery occlusion: a systematic review and meta-analysis
Q28210949Therapy for early reperfusion after stroke
Q36742130Third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke
Q42907046Thrombi of Different Pathologies: Implications for Diagnosis and Treatment
Q38198740Thrombolysis and reperfusion: advanced understanding of early management strategies in acute ischemic stroke
Q47924174Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: Expert opinion
Q24194788Thrombolysis for acute ischaemic stroke
Q24240067Thrombolysis for acute ischaemic stroke
Q24247962Thrombolysis for acute ischaemic stroke
Q42668646Thrombolysis for acute ischaemic stroke with alteplase in an Asian population: results of the multicenter, multinational Safe Implementation of Thrombolysis in Stroke-Non-European Union World (SITS-NEW).
Q48139385Thrombolysis for acute ischemic stroke: does it work?--the con position
Q33938946Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study
Q33794859Thrombolysis for acute stroke
Q34107350Thrombolysis for acute stroke: is it for everyone?
Q31109436Thrombolysis for ischemic stroke: an update
Q53571708Thrombolysis for stroke in the elderly.
Q83376792Thrombolysis for stroke: policy should be based on science, and not on politics, money or fear of malpractice
Q92601645Thrombolysis in Cerebral Infarction Grade 2C or 3 Represents a Better Outcome than 2B for Endovascular Thrombectomy in Acute Ischemic Stroke: A Network Meta-Analysis
Q34164541Thrombolysis in acute ischaemic stroke
Q33217342Thrombolysis in acute ischaemic stroke: a guide to patient selection
Q40696300Thrombolysis in acute ischemic stroke is associated with lower long-term hospital bed day use: A nationwide propensity score-matched follow-up study.
Q35631279Thrombolysis in chinese ischemic stroke patients with renal dysfunction
Q34143581Thrombolysis in ischemic strokes with no arterial occlusion
Q36226503Thrombolysis in patients older than 80 years with acute ischaemic stroke: Canadian Alteplase for Stroke Effectiveness Study
Q77466547Thrombolysis in stroke beyond three hours: Targeting patients with diffusion and perfusion MRI
Q38075577Thrombolysis in the developing world: is there a role for streptokinase?
Q48552966Thrombolysis induces cerebral hemorrhage in a mouse model of cerebral amyloid angiopathy
Q45974947Thrombolysis on ischemic stroke patients with decreased level of consciousness within 4.5 h.
Q34561985Thrombolysis risk prediction: applying the SITS-SICH and SEDAN scores in South African patients
Q37879682Thrombolysis treatment for acute stroke: issues of efficacy and utilization in women
Q81963102Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study
Q42610437Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study.
Q36870040Thrombolysis with alteplase for acute ischemic stroke: review of SITS-MOST and other Phase IV studies
Q33646036Thrombolysis, stroke units and other strategies for reducing acute stroke costs.
Q37571432Thrombolysis, stroke-unit admission and early rehabilitation in elderly patients
Q48294695Thrombolytic Therapy in Acute Ischemic Stroke
Q31156580Thrombolytic Treatment for Ischaemic Stroke: Could the Crisis of Confidence Have Been Avoided by Better Analysis of Trial Data?
Q73521065Thrombolytic properties of leukocytes from peripheral blood in healthy subjects and in patients with acute cerebral ischemia
Q36227021Thrombolytic therapy for acute ischaemic stroke in octogenarians: selection by magnetic resonance imaging improves safety but does not improve outcome
Q77939627Thrombolytic therapy for acute ischemic stroke
Q78022218Thrombolytic therapy for acute ischemic stroke
Q35552867Thrombolytic therapy for acute ischemic stroke beyond three hours
Q36106814Thrombolytic therapy for acute ischemic stroke: 3 h and beyond
Q81969469Thrombolytic therapy for acute stroke
Q33632565Thrombolytic therapy for acute stroke in Austria: data from the Safe Implementation of Thrombolysis in Stroke (SITS) register
Q33398481Thrombolytic therapy for patients who wake-up with stroke
Q33873285Thrombolytic therapy for stroke: a review with particular reference to elderly patients.
Q36472612Thrombolytic therapy in pregnancy
Q35081866Thrombolytic therapy: clinical applications
Q36254835Thrombolytic treatment of acute cerebral infarction
Q31029314Thrombolytic-Related Asymptomatic Hemorrhagic Transformation Does Not Deteriorate Clinical Outcome: Data from TIMS in China
Q47941678Time for a Time Window Extension: Insights from Late Presenters in the ESCAPE Trial
Q48829887Time to hospital admission and start of treatment in patients with ischemic stroke in northern Italy and predictors of delay
Q39933423Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials
Q51626282Timing of Symptomatic Infarct Swelling Following Intravenous Thrombolysis in Acute Middle Cerebral Artery Infarction: A Case-Control Study.
Q56336828Tissue-type plasminogen activator as a therapeutic target in stroke
Q40207994To Treat or Not to Treat M2 Occlusions? The Question (and Answer) From a Single Institution
Q37605386Total time of operation is a risk factor of stroke-associated pneumonia in acute ischemic stroke patients with intra-arterial treatment
Q37409117Translating research into practice: lessons from trials of thrombolysis in acute stroke.
Q28196628Treating the acute stroke patient as an emergency: current practices and future opportunities
Q45799384Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study
Q38543305Treatment of acute ischemic stroke: from fibrinolysis to neurointervention
Q37451515Treatment of acute ischemic stroke: intravenous and endovascular therapies
Q40063905Treatment of acute ischemic stroke: systemic or local?
Q48473559Treatment of acute stroke: a misconception
Q38541197Treatment of acute stroke: an update
Q80852679Treatment of cerebellar masses
Q33897269Treatment time-specific number needed to treat estimates for tissue plasminogen activator therapy in acute stroke based on shifts over the entire range of the modified Rankin Scale.
Q41588199Treatment with recombinant tissue plasminogen activator (r-TPA) induces neutrophil degranulation in vitro via defined pathways
Q53135352Treatment with tPA predicts better outcome even if MCA occlusion persists.
Q37584739Trends of the Incidence of Ischemic Stroke Thrombolysis over Seven Years and One-Year Outcome: A Population-Based Study in Joinville, Brazil
Q26853103Twenty-Year History of the Evolution of Stroke Thrombolysis With Intravenous Alteplase to Reduce Long-Term Disability
Q80304426Ultra-early doppler sonography for stroke
Q39532900Ultra-fast three-dimensional MR perfusion imaging of the entire brain in acute stroke assessment
Q37244632Ultrasound enhanced thrombolysis for stroke.
Q37176753Ultrasound enhanced thrombolysis in acute arterial ischemia.
Q37203476Ultrasound enhanced thrombolysis: applications in acute cerebral ischemia
Q48430318Ultrasound-enhanced thrombolysis for stroke: clinical significance
Q36864308Ultrasound-enhanced thrombolysis in acute ischemic stroke: potential, failures, and safety
Q39395552Update on Neurocritical Care of Stroke
Q33956289Update on intravenous tissue plasminogen activator for acute stroke: from clinical trials to clinical practice
Q48558308Update on the effects of treatment with recombinant tissue-type plasminogen activator (rt-PA) in acute ischemic stroke.
Q34086851Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
Q53649850Use of CT angiography in patient selection for thrombolytic therapy.
Q41635141Use of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke Patients: Evaluation of Clinical Outcomes
Q35108125Use of antithrombotics after hemorrhagic transformation in acute ischemic stroke
Q24793478Use of diffusion and perfusion magnetic resonance imaging as a tool in acute stroke clinical trials
Q38078028Use of intravenous recombinant tissue plasminogen activator in patients outside the defined criteria: safety and feasibility issues
Q37507984Use of neuroimaging in acute stroke trials
Q48676504Usefulness of CT angiography for therapeutic decision making in thrombolyzing intubated patients with suspected basilar artery thrombosis.
Q74033011Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score
Q35152697Various blood glucose parameters that indicate hyperglycemia after intravenous thrombolysis in acute ischemic stroke could predict worse outcome
Q42380288Visibility of CT Early Ischemic Change Is Significantly Associated with Time from Stroke Onset to Baseline Scan beyond the First 3 Hours of Stroke Onset
Q34038274Wake-up stroke: clinical and neuroimaging characteristics
Q38392999What causes intracerebral bleeding after thrombolysis for acute ischaemic stroke? Recent insights into mechanisms and potential biomarkers.
Q46768047What should be defined as good outcome in stroke trials; a modified Rankin score of 0-1 or 0-2?
Q36533168Which model of stroke unit is better for stroke patient management?
Q36245471Why have neuro-protectants failed?: lessons learned from stroke trials.
Q55306230Why not Intravenous Thrombolysis in Patients with Recurrent Stroke within 3 Months?
Q47223299Worse Outcome in Stroke Patients Treated with rt-PA Without Early Reperfusion: Associated Factors
Q82060749[C-reactive protein in the acute phase of ischemic stroke]
Q53375071[Computed tomography in acute ischemic stroke. Current developments compared with stroke MRI].
Q82958456[Current management of acute isquemic stroke]
Q81691991[European Stroke Organisation 2008 guidelines for managing acute cerebral infarction or transient ischemic attack : part 2]
Q74334263[Fibrinolytic treatment in acute cerebrovascular accident]
Q81357386[Imaging of cerebral ischemia within first hours: computed tomography (CT)]
Q82387389[Implementation of thrombolysis in acute stroke--10-year results of the Innsbruck stroke registry]
Q81691889[Intra-arterial thrombolysis of the middle cerebral artery: an overview]
Q53490659[Intravenous rt-PA for acute ischemic stroke: 69 consecutive patients managed in an emergency stroke centre]
Q53662088[Intravenous tissue-type plasminogen activator for the treatment of acute cerebral ischemia].
Q81920598[Ischemic stroke in the elderly--analysis of the Austrian Stroke Unit Registry]
Q82621794[Ischemic stroke patients following intravenous thrombolysis. Outcome in a regional stroke center]
Q81703832[Recent studies concerning treatment of acute, ischemic infarcts]
Q79928804[Recommendations of the European Stroke Initiative (EUSI) for treatment of ischemic stroke--update 2003. I. organization and acute therapy]
Q83217445[Stroke MRI for risk assessment of intracerebral hemorrhage associated with thrombolytic therapy]
Q80179571[Stroke and thrombolysis in a basic hospital. A possible duty]
Q79331100[Treatment with intravenous rt-PA in a general hospital context: A review of the Saint-Jean Hospital experience from Perpignan, France]
Q78784672[Unblocking arteries to save brains: thrombolysis in patients with stroke]
Q53304411tPA treatment for acute ischaemic stroke in patients with leukoaraiosis.

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