Ion channel phosphorylopathy: a link between genomic variation and human disease

scientific article published on 24 August 2012

Ion channel phosphorylopathy: a link between genomic variation and human disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/CMDC.201200236
P698PubMed publication ID22927196
P5875ResearchGate publication ID230748761

P2093author name stringSaverio Gentile
P2860cites workA molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndromeQ24316980
The protein kinase complement of the human genomeQ24324497
Rac GTPase signaling through the PP5 protein phosphataseQ24546372
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autismQ28117072
Rapid signaling at the plasma membrane by a nuclear receptor for thyroid hormoneQ28303035
Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascadeQ28361745
Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.Q30652695
Structural basis of protein kinase C isoform functionQ33973406
Ion Channel Voltage Sensors: Structure, Function, and PathophysiologyQ34139997
Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2.Q34150435
Kinetic and catalytic mechanisms of protein kinasesQ34465987
Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helicesQ34944217
Inherited neuronal ion channelopathies: new windows on complex neurological diseasesQ35226085
Realistic simulation of the activation of voltage-gated ion channelsQ35807726
The human ERG1 channel polymorphism, K897T, creates a phosphorylation site that inhibits channel activityQ36936368
Channelopathies: a reviewQ37060980
Potassium channel phosphorylation in excitable cells: providing dynamic functional variability to a diverse family of ion channelsQ37082375
The role of calmodulin kinase II in myocardial physiology and diseaseQ37192039
Genetics and cardiac channelopathies.Q37729709
Thyroid hormone receptor TRbeta1 mediates Akt activation by T3 in pancreatic beta cells.Q40172304
Voltage-gated ion channels and electrical excitabilityQ41737177
Common Genetic Variation in KCNH2 Is Associated With QT Interval DurationQ57072945
P433issue10
P304page(s)1757-1761
P577publication date2012-08-24
P1433published inChemMedChemQ2962252
P1476titleIon channel phosphorylopathy: a link between genomic variation and human disease
P478volume7

Reverse relations

cites work (P2860)
Q38465804Identification of drug targets related to the induction of ventricular tachyarrhythmia through a systems chemical biology approach
Q40639170Isoform-specific dynamic translocation of PKC by α1-adrenoceptor stimulation in live cells
Q51119613Roles of PKC Isoforms in PMA-Induced Modulation of the hERG Channel (Kv11.1).

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