Septo-hippocampal cholinergic and neurotrophin markers in age-induced cognitive decline

scientific article published in July 1998

Septo-hippocampal cholinergic and neurotrophin markers in age-induced cognitive decline is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0197-4580(98)00072-4
P698PubMed publication ID9733168

P2093author name stringKent C
Gallagher M
Sugaya K
Greene R
Robbins M
McKinney M
Bryan D
Personett D
Skiba E
P2860cites workMessenger RNAs of beta-amyloid precursor protein and prion protein are regulated by nerve growth factor in PC12 cellsQ48160234
Decreased level of nerve growth factor (NGF) and its messenger RNA in the aged rat brainQ48181791
Nerve growth factor content of rat brain increases following basal-forebrain lesions induced by ibotenic acid but not by electrolysisQ48205347
Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC12 cells and variant PC12S cellsQ48369699
Septal cholinergic afferents regulate expression of brain-derived neurotrophic factor and beta-nerve growth factor mRNA in rat hippocampusQ48570020
Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during agingQ48602029
Brain aging: changes in the nature of information coding by the hippocampus.Q48679389
Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of MeynertQ48737230
Chronic treatment with scopolamine and physostigmine changes nerve growth factor (NGF) receptor density and NGF content in rat brainQ48786937
Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairmentsQ48832628
Expression and polarization of VGF in developing hippocampal neuronsQ48887833
Differential regulation of hippocampal neurotrophins during aging in rats.Q48938702
Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water mazeQ49154769
Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signalsQ50335838
Age and neurochemical correlates of radial maze performance in rats.Q52103111
Intact spatial learning in both young and aged rats following selective removal of hippocampal cholinergic input.Q52201173
Molecular indices of neuronal and glial plasticity in the hippocampal formation in a rodent model of age-induced spatial learning impairment.Q52201512
Age-related decrease in cholinergic synaptic transmission in three hippocampal subfields.Q52201807
Hippocampal muscarinic receptor function in spatial learning-impaired aged rats.Q52204908
Stimulation of vgf gene expression by NGF is mediated through multiple signal transduction pathways involving protein phosphorylationQ60977080
Distribution of nerve growth factor receptor-like immunoreactivity in the adult rat central nervous system. Effect of colchicine and correlation with the cholinergic system--II. Brainstem, cerebellum and spinal cordQ68455805
Nerve growth factor and Alzheimer's diseaseQ68906987
Pharmacological induction of nerve growth factor mRNA in adult rat brainQ70494144
Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged ratsQ71923911
The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from chinese hamster ovary-m1 cellsQ72058907
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptorsQ24294213
GAP-43: an intrinsic determinant of neuronal development and plasticityQ28303146
Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervationQ36548591
VGF expression in the brainQ36712461
Simplified RT/PCR quantitation of gene transcripts in cultured neuroblastoma (SN49) and microglial (BV-2) cells using capillary electrophoresis and laser-induced fluorescence.Q36820761
Preserved neuron number in the hippocampus of aged rats with spatial learning deficitsQ37368259
Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged ratsQ37739715
Transcriptional regulation of neuromodulin (GAP-43) in mouse neuroblastoma clone N1E-115 as evaluated by the RT/PCR methodQ38330242
Increased beta-amyloid precursor protein mRNA in the rat cerebral cortex and hippocampus after chronic systemic atropine treatmentQ38357595
Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseasesQ38715616
Nerve growth factor receptors in the central nervous systemQ39294106
Role of neurotrophins in cholinergic-neurone function in the adult and aged CNS.Q40397642
Hippocampal NGF levels are not reduced in the aged Fischer 344 rat.Q41146600
Nerve growth factor and ras regulate beta-amyloid precursor protein gene expression in PC12 cellsQ41190133
The use of animal models to study the effects of aging on cognitionQ41359503
Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cellsQ41361359
Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of beta-amyloid precursor mRNAs in the PC12 cell lineQ41678049
Relationship of age-related decline across several behavioral domainsQ41763138
Cholinesterase inhibitors increase secretion of APPs in rat brain cortexQ42276951
Activation of basal forebrain cholinergic neurons differentially regulates brain-derived neurotrophic factor mRNA expression in different projection areasQ42462320
Differential expression of p140trk, p75NGFR and growth-associated phosphoprotein-43 genes in nucleus basalis magnocellularis, thalamus and adjacent cortex following neocortical infarction and nerve growth factor treatmentQ42474399
Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1.Q42475163
Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated TrkA expression in the medial septum of aged ratsQ42477110
Selective immunotoxic lesions of basal forebrain cholinergic cells: effects on learning and memory in ratsQ42479014
Distribution of nerve growth factor receptor-like immunoreactivity in the adult rat central nervous system. Effect of colchicine and correlation with the cholinergic system--I. ForebrainQ42479615
Spatial memory deficits in aged rats: contributions of the cholinergic system assessed by ChAT.Q42485831
NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat.Q42494413
Differential expression of GAP-43 mRNA in adult central cholinergic neuronal populationsQ42496416
Spatial learning deficits in the aged rat: neuroanatomical and neurochemical correlatesQ42501056
Role of the cholinergic system in the regulation of neurotrophin synthesisQ42523773
Intact spatial learning following lesions of basal forebrain cholinergic neurons.Q42524918
The effect of cholinesterase inhibitors on the secretion of APPS from rat brain cortexQ42556618
Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: evidence from lesion and chronic cholinergic drug treatment studiesQ44219936
Markers for biogenic amines in the aged rat brain: relationship to decline in spatial learning abilityQ44799559
Hippocampal nerve growth factor levels are related to spatial learning ability in aged ratsQ45256041
Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampusQ46218145
vgf A neurotrophin-inducible gene expressed in neuroendocrine tissuesQ47874963
Increased NGF-like activity in young but not aged rat hippocampus after septal lesionsQ48134645
Relationship of APP mRNA transcripts and levels of NGF and low-affinity NGF receptors to behavioral measures of age-related cognitive dysfunctionQ48144133
P433issue4
P304page(s)351-361
P577publication date1998-07-01
P1433published inNeurobiology of AgingQ7002141
P1476titleSepto-hippocampal cholinergic and neurotrophin markers in age-induced cognitive decline
P478volume19

Reverse relations

cites work (P2860)
Q469213073T hippocampal glutamate-glutamine complex reflects verbal memory decline in aging
Q51990282Age-associated alterations of hippocampal place cells are subregion specific.
Q48714719Age-related changes in rhythmically bursting activity in the medial septum of rats
Q48770233Age-related decline of presumptive inhibitory synapses in the sensorimotor cortex as revealed by the physical disector
Q37300518BDNF transcripts, proBDNF and proNGF, in the cortex and hippocampus throughout the life span of the rat.
Q52172205Changes in brain nerve growth factor levels and nerve growth factor receptors in rats exposed to environmental enrichment for one year.
Q42487547Cholinergic medial septum neurons do not degenerate in aged 129/Sv control or p75(NGFR)-/-mice
Q34698981Chronic oral estrogen affects memory and neurochemistry in middle-aged female mice.
Q44844961Cognitive aging and the hippocampus: how old rats represent new environments.
Q36979247Cognitive aging: a common decline of episodic recollection and spatial memory in rats
Q48713838Effect of age and cognitive status on basal level AP-1 activity in rat hippocampus
Q37416711Enhanced calcium buffering in F344 rat cholinergic basal forebrain neurons is associated with age-related cognitive impairment
Q42486533Enlarged cholinergic forebrain neurons and improved spatial learning in p75 knockout mice
Q48020423Exogenous NGF restores endogenous NGF distribution in the brain of the cognitively impaired aged rat.
Q42509543Fermented Citrus reticulata (ponkan) fruit squeezed draff that contains a large amount of 4'-demethylnobiletin prevents MK801-induced memory impairment.
Q36755714Higher levels of estradiol replacement correlate with better spatial memory in surgically menopausal young and middle-aged rats
Q48206869Hilar neuropeptide Y interneuron loss in the aged rat hippocampal formation
Q48150837Hippocampal gene expression profiling reveals the possible involvement of Homer1 and GABA(B) receptors in scopolamine-induced amnesia.
Q42564525Hippocampal theta, gamma, and theta-gamma coupling: effects of aging, environmental change, and cholinergic activation
Q33992022Identification of a novel biomarker candidate, a 4.8-kDa peptide fragment from a neurosecretory protein VGF precursor, by proteomic analysis of cerebrospinal fluid from children with acute encephalopathy using SELDI-TOF-MS
Q42483907Immunohistochemical and neurochemical correlates of learning deficits in aged rats
Q37764494Impact of the hypothalamic-pituitary-adrenal/gonadal axes on trajectory of age-related cognitive decline
Q33597273Increased BDNF may not be associated with cognitive impairment in heroin-dependent patients
Q34615552Learning to remember: cognitive training-induced attenuation of age-related memory decline depends on sex and cognitive demand, and can transfer to untrained cognitive domains
Q36993355Lifelong environmental enrichment in rats: impact on emotional behavior, spatial memory vividness, and cholinergic neurons over the lifespan.
Q30815615Microarray analysis of gene expression in the supraoptic nucleus of normoosmotic and hypoosmotic rats
Q28483618Monitoring CSF proteome alterations in amyotrophic lateral sclerosis: obstacles and perspectives in translating a novel marker panel to the clinic
Q30491828Neurocognitive aging: prior memories hinder new hippocampal encoding
Q24647788Neuropeptides in depression: role of VGF
Q35078498Neuroscientists as cartographers: mapping the crossroads of gonadal hormones, memory and age using animal models
Q24619952Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity
Q34441691Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults
Q37217001Patterns of neurotrophin protein levels in male and female Fischer 344 rats from adulthood to senescence: how young is "young" and how old is "old"?
Q41713135Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons.
Q43806238Signatures of hippocampal oxidative stress in aged spatial learning-impaired rodents
Q34333481Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signaling as a biological marker of early impairment
Q44462482Testosterone, but not nonaromatizable dihydrotestosterone, improves working memory and alters nerve growth factor levels in aged male rats
Q48967639Topography of neurochemical alterations in the CNS of aged rats

Search more.