Sensitization and kindling phenomena in mood, anxiety, and obsessive-compulsive disorders: the role of serotonergic mechanisms in illness progression

scientific article published in August 1998

Sensitization and kindling phenomena in mood, anxiety, and obsessive-compulsive disorders: the role of serotonergic mechanisms in illness progression is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0006-3223(98)00144-9
P698PubMed publication ID9693391

P50authorRobert M. PostQ87613308
P2093author name stringWeiss SR
P2860cites workSerotonergic agents that activate 5HT2A receptors prevent NMDA antagonist neurotoxicityQ28257464
Electrode placement and kindling-induced experiemental epilepsyQ29307002
More hippocampal neurons in adult mice living in an enriched environmentQ29617733
Stress and antidepressants differentially regulate neurotrophin 3 mRNA expression in the locus coeruleusQ33926970
Transduction of psychosocial stress into the neurobiology of recurrent affective disorderQ33969745
A molecular and cellular theory of depressionQ34064955
Effects of thyrotropin-releasing hormone in depressionQ34202276
A permanent change in brain function resulting from daily electrical stimulationQ34225550
Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult ratsQ34365345
Ultra-rapid and ultradian cycling in bipolar affective illnessQ34399943
Effects of intrathecal thyrotropin-releasing hormone (protirelin) in refractory depressed patientsQ34419936
Serotonin neurotransmission in cocaine sensitizationQ35230467
Ziskind-Somerfeld Research Award 1992. Endogenous biochemical abnormalities in affective illness: therapeutic versus pathogenicQ35535570
Contingent tolerance to the anticonvulsant effects of carbamazepine: relationship to loss of endogenous adaptive mechanismsQ71721208
Tryptophan depletion in stable lithium-treated patients with bipolar disorder in remissionQ72526170
Intra-hippocampal injection of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) inhibits partial and generalized seizures induced by kindling stimulation in catsQ72666871
Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptorsQ73486409
Conditioned sensitization to the psychomotor stimulant cocaineQ36330323
Anterior paralimbic mediation of procaine-induced emotional and psychosensory experiencesQ36788755
Biochemistry of Mental DepressionQ38065156
Lithium and serotonin function: implications for the serotonin hypothesis of depressionQ38138445
Emotional deprivation and growth retardation simulating idiopathic hypopituitarism. I. Clinical evaluation of the syndromeQ39108500
Emotional deprivation and growth retardation simulating idiopathic hypopituitarism. II. Endocrinologic evaluation of the syndromeQ39108505
Central serotonin metabolism and frequency of depressionQ39595688
Evidence against serotonin involvement in the tonic component of electrically induced convulsions and in carbamazepine anticonvulsant activityQ39715602
Psychosocial dwarfism: a critical review of the evidenceQ40139906
Serotonergic function in the affective disorders: the effect of antidepressants and lithium on the 5-hydroxytryptophan-induced increase in serum cortisolQ40181747
Lamotrigine. An update of its pharmacology and therapeutic use in epilepsyQ40932340
Neurochemical correlates of antiepileptic drugs in the genetically epilepsy-prone rat (GEPR).Q40933225
Antidepressant-induced mania and cycle acceleration: a controversy revisitedQ40977115
A speculative model of affective illness cyclicity based on patterns of drug tolerance observed in amygdala-kindled seizuresQ41189037
Obsessive-compulsive disorder and serotonin: is there a connection?Q41243764
The place of anticonvulsant therapy in bipolar illnessQ41257728
Lithium increases 5-HT-mediated prolactin release.Q41262711
Kindling versus quenching. Implications for the evolution and treatment of posttraumatic stress disorderQ41544953
Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitroQ41953702
Lithium Increases Serotonin Release and Decreases Serotonin Receptors in the HippocampusQ42451644
Regional effects of sodium valproate on extracellular concentrations of 5-hydroxytryptamine, dopamine, and their metabolites in the rat brain: an in vivo microdialysis studyQ42455719
Comparative antidepressant effects of intravenous and intrathecal thyrotropin-releasing hormone: confounding effects of tolerance and implications for therapeutics.Q42649389
Effects of carbamazepine on 5-hydroxytryptamine function in rodentsQ43536059
Comparison of the effects of benzodiazepines and other anticonvulsant drugs on synthesis and utilization of 5-HT in mouse brainQ43545746
Effect of amygdala kindling on the in vivo release of GABA and 5-HT in the dorsal raphe nucleus in freely moving ratsQ44670467
Anticonvulsant effect of intranigral fluoxetineQ44925768
Selected CSF biochemistry and gabapentin concentrations in the CSF and plasma in patients with partial seizures after a single oral dose of gabapentinQ45012245
Reduction of prefrontal cortex glucose metabolism common to three types of depressionQ45097380
Childhood physical abuse and combat-related posttraumatic stress disorder in Vietnam veteransQ45336206
Quantitative and qualitative aspects on the distribution of 5-HT and its coexistence with substance P and TRH in cat ventral medullary neuronsQ48102258
Serotonin and kindling development.Q48197986
Experimental epileptogenesis: Kindling-induced epilepsy in ratsQ48218679
Anticonvulsant effect of fluoxetine on focally evoked limbic motor seizures in ratsQ48326165
Alterations in mRNA of enkephalin, dynorphin and thyrotropin releasing hormone during amygdala kindling: an in situ hybridization studyQ48427526
Does the engram of kindling model the engram of normal long term memory?Q48433758
Role of serotonin receptor subtype in seizures kindled from the feline hippocampusQ48456430
Chronic cocaine enhances serotonin autoregulation and serotonin uptake bindingQ48476385
Behavioral and electroencephalographic effects of a serotonin receptor agonist (5-methoxy-N,N-dimethyltryptamine) in a feline model of photosensitive epilepsyQ48493131
Persistent seizure susceptibility and recurrent spontaneous seizures in kindled catsQ48502732
Repetitive transcranial magnetic stimulation for posttraumatic stress disorderQ48506639
Role of central dopaminergic and 5-hydroxytryptaminergic projections in the behavioral responses elicited by thyrotropin-releasing hormone in ratsQ48559193
Metabolic and behavioral consequences of lidocaine-kindled seizuresQ48589074
Actions of nimodipine on the serotonergic systems of rat brainQ48630788
Effects of subchronic treatment with valproate on L-5-HTP-induced cortisol responses in mania: evidence for increased central serotonergic neurotransmissionQ48660071
Effects of the 5-HT3 receptor agonist 1-(m-chlorophenyl)-biguanide in the rat kindling model of epilepsyQ48683765
Regional expression of c-fos mRNA in rat brain during the evolution of amygdala kindled seizuresQ48685421
The effect of valproic acid on 5-hydroxytryptamine and 5-hydroxyindoleacetic acid concentration in hippocampal dialysates in vivoQ48686963
Effect of prefrontal repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: a preliminary studyQ48701540
Anticonvulsant doses of carbamazepine increase hippocampal extracellular serotonin in genetically epilepsy-prone rats: dose response relationshipsQ48707882
Effects of amygdala kindling and electroconvulsive seizures on the expression of corticotropin-releasing hormone in the rat brainQ48742032
Abnormalities of indoleamines in affective disordersQ48769664
Role of serotonin receptor subtypes in the development of amygdaloid kindling in ratsQ48802672
Effects of diazepam and diphenylhydantoin on elicited and spontaneous seizures in kindled rats: a double dissociationQ48808064
Transplantation of serotonergic neurons into the 5,7-DHT-lesioned rat olfactory bulb restores the parameters of kindlingQ48952724
Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression.Q48960526
Lithium treatment effect on serotonin functionQ49076879
Effects of carbamazepine on dopamine- and serotonin-mediated neuroendocrine responses.Q49125493
Recurrence in affective disorder. I. Case register study.Q50897602
Tryptophan and 5-HT in psychiatric illness.Q51118067
Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression.Q51120793
Lithium treatment and serotoninergic function. Neuroendocrine and behavioral responses to intravenous tryptophan in affective disorder.Q51181260
Life events and course of illness in patients with panic disorder.Q51209617
Life stress, chronic subclinical symptoms and vulnerability to clinical depression.Q51210593
Blockade of cocaine sensitization and tolerance by the co-administration of ondansetron, a 5-HT3 receptor antagonist, and cocaine.Q51547024
Serotonin and Dopamine Sensitization in the Nucleus Accumbens, Ventral Tegmental Area, and Dorsal Raphe Nucleus Following Repeated Cocaine AdministrationQ51652814
Amygdala-kindled seizures increase the expression of corticotropin-releasing factor (CRF) and CRF-binding protein in GABAergic interneurons of the dentate hilus.Q52003929
Transcranial magnetic stimulation: a potential new frontier in psychiatry.Q52013128
Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus.Q52017804
Colocalization of TRH mRNA and Fos-like Immunoreactivity in Limbic Structures Following Amygdala Kindling.Q52034129
Cerebrospinal fluid neurochemistry in children and adolescents with obsessive-compulsive disorderQ52046635
Lithium increases 5-HT-mediated neuroendocrine responses in tricyclic resistant depression.Q54368435
Increased plasma free serotonin but unchanged platelet serotonin in bipolar patients treated chronically with lithiumQ60641599
The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experimentsQ64382984
Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activityQ64386018
Gabapentin augments whole blood serotonin in healthy young menQ68002680
Fluoxetine, a selective serotonin-uptake inhibitor, enhances the anticonvulsant effects of phenytoin, carbamazepine, and ameltolide (LY201116)Q68056289
Recurrent brief depression: a new subtype of affective disorderQ68423073
The duration, nature and recurrence rate of brief depressionsQ68688738
Positive effects of tactile versus kinesthetic or vestibular stimulation on neuroendocrine and ODC activity in maternally-deprived rat pupsQ68809771
Local cerebral glucose metabolic rates in obsessive-compulsive disorder. A comparison with rates in unipolar depression and in normal controlsQ68816370
Elevation of immunoreactive CSF TRH in depressed patientsQ70412461
Impact of cumulative lifetime trauma and recent stress on current posttraumatic stress disorder symptoms in holocaust survivorsQ70798816
Serotonin turnover rate, [3H]paroxetine binding sites, and 5-HT1A receptors in the hippocampus of rats subchronically treated with clonazepamQ70921108
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectKindlingQ6410625
P304page(s)193-206
P577publication date1998-08-01
P1433published inBiological PsychiatryQ4914961
P1476titleSensitization and kindling phenomena in mood, anxiety, and obsessive-compulsive disorders: the role of serotonergic mechanisms in illness progression
P478volume44

Reverse relations

cites work (P2860)
Q37250308Acute tryptophan depletion evokes negative mood in healthy females who have previously experienced concurrent negative mood and tryptophan depletion
Q44867008Affective disorder and epilepsy comorbidity: implications for development of treatments, preventions and diagnostic approaches
Q50644430Amygdalar hyperactivity, a fear-related link between panic disorder and mesiotemporal epilepsy.
Q34392445Antiepileptic drugs: affective use in autism spectrum disorders.
Q44341298Central d-Ala2-Met5-enkephalinamide μ/δ-opioid receptor activation blocks behavioral sensitization to cholecystokinin in CD-1 mice
Q33935028Childhood maltreatment, juvenile disorders and adult post-traumatic stress disorder: a prospective investigation
Q30371216Chronic stress and brain plasticity: Mechanisms underlying adaptive and maladaptive changes and implications for stress-related CNS disorders
Q37351170Co-morbid major depression and generalized anxiety disorders in the National Comorbidity Survey follow-up
Q36327079Delay and failure in treatment seeking after first onset of mental disorders in the World Health Organization's World Mental Health Survey Initiative
Q34336404Delays in initial treatment contact after first onset of a mental disorder
Q52655616Delays in making initial treatment contact after the first onset of mental health disorders in the Argentinean Study of Mental Health Epidemiology.
Q35836944Development and preliminary validation of a scale to measure self-efficacy in seeking mental health care (SE-SMHC).
Q44056512Diabetic ketoacidosis depletes plasma tryptophan
Q36540209Early life trauma exposure and stress sensitivity in young children
Q50716557Emotion modelling towards affective pathogenesis.
Q47823541Functional brain-imaging correlates of negative affectivity and the onset of first-episode depression.
Q31146112Hippocampal gene expression changes underlying stress sensitization and recovery
Q95579823How evolutionary psychiatry can advance psychopharmacology
Q36019546How to improve testing when trying to predict inmate suicidal behavior
Q38463217Impact of Child Maltreatment on Attachment and Social Rank Systems: Introducing an Integrated Theory
Q33938089Impact of substance abuse on the course and treatment of bipolar disorder
Q95800936Improving the Prediction of Suicidal Behavior in Youth
Q73625619Latency and episodes before treatment: response to lithium maintenance in bipolar I and II disorders
Q30368679Learning models of PTSD: Theoretical accounts and psychobiological evidence.
Q36634426Life events and juvenile bipolar disorder: conceptual issues and early findings
Q30474805Life events in bipolar disorder: towards more specific models
Q33958613Localization of 5-HT(2A) receptors on dopamine cells in subnuclei of the midbrain A10 cell group
Q34543797Major depression epidemiology from a diathesis-stress conceptualization
Q37730644Mechanisms of illness progression in the recurrent affective disorders
Q30640247Mitochondrial dysfunction in bipolar disorder
Q30359575Modeling mania in preclinical settings: A comprehensive review.
Q48497073Multiparity reveals the blunting effect of breastfeeding on physiological reactivity to psychological stress
Q89684509Neural networks and the anti-inflammatory effect of transcutaneous auricular vagus nerve stimulation in depression
Q35587678Neurobiology of antidepressant withdrawal: implications for the longitudinal outcome of depression
Q30494165Nitric oxide as inflammatory mediator in post-traumatic stress disorder (PTSD): evidence from an animal model.
Q37079684Non-suicidal self-injury and life stress: A systematic meta-analysis and theoretical elaboration
Q73575704On episode sensitization in recurrent affective disorders: the role of noise
Q52020541On the impact of episode sensitization on the course of recurrent affective disorders.
Q35121794Ontogenesis of behavioral sensitization and conditioned place preference induced by psychostimulants in laboratory rodents.
Q51931050Pilot sample of very early onset bipolar disorder in a military population moderates the association of negative life events and non-fatal suicide attempt.
Q48444347Prestige and bipolarity
Q66476120Re-experiencing 9/11-related PTSD symptoms following exposure to Hurricane Sandy
Q46734599Recurrence in major depressive disorder: a neurocognitive perspective
Q36272491Recurrent brief depression revisited
Q35054419Recurrent brief depression--past and future
Q34730291Relating the bipolar spectrum to dysregulation of behavioural activation: a perspective from dynamical modelling
Q47575365Relation between lifespan polytrauma typologies and post-trauma mental health
Q39267552Repeated fear-induced diurnal rhythm disruptions predict PTSD-like sensitized physiological acute stress responses in F344 rats
Q34633155School-based intervention to improve the mental health of low-income, secondary school students in Santiago, Chile (YPSA): study protocol for a randomized controlled trial
Q46910398Specific traumatic events during childhood as risk factors for posttraumatic stress disorder development in adults.
Q41978796Stress sensitization following a disaster: a prospective study
Q44892905Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus
Q40106548Stressful life events severity in patients with first and recurrent depressive episodes
Q33362466The crossroads of anxiety: distinct neurophysiological maps for different symptomatic groups
Q30494370The emerging modern face of mood disorders: a didactic editorial with a detailed presentation of data and definitions
Q43693778The epidemiology of trauma, PTSD, and other posttrauma disorders
Q34718252The impact of epidemic violence on the prevalence of psychiatric disorders in Sao Paulo and Rio de Janeiro, Brazil
Q56767280The inflammatory response following delivery is amplified in women who previously suffered from major depression, suggesting that major depression is accompanied by a sensitization of the inflammatory response system
Q33934637The neurobiology of anxiety disorders: implications for psychiatric nursing practice
Q33619910The psychopathology and treatment of bipolar disorder
Q58543551The role of modifiable health-related behaviors in the association between PTSD and respiratory illness
Q43496667The role of stress sensitization in progression of posttraumatic distress following deployment
Q34856249The use of newer anticonvulsants in neuropsychiatric disorders
Q47988196Trauma exposure and post-traumatic stress disorder in a cohort of pregnant Peruvian women
Q45373060Treatment gap in common mental disorders: the Singapore perspective
Q37681560Treatment strategies for obsessive-compulsive disorder
Q47558697Twelve-month prevalence rates of mental disorders and service use in the Argentinean Study of Mental Health Epidemiology
Q38546050Weighing the Costs of Disaster: Consequences, Risks, and Resilience in Individuals, Families, and Communities
Q51904601What's in a name? Is accurate recognition and labelling of mental disorders by young people associated with better help-seeking and treatment preferences?
Q23918313World Trade Center disaster and sensitization to subsequent life stress: a longitudinal study of disaster responders
Q43493983[Mindfulness-based cognitive therapy : current status and future applications].
Q79987372[Recurrent depression and life events: ACTUEL survey]