Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach

scientific article published on 21 November 2017

Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.HUMIMM.2017.11.008
P932PMC publication ID5963722
P698PubMed publication ID29175110

P2093author name stringDavid H Sachs
Thomas R Spitzer
Hajime Sasaki
Joren C Madsen
Yi-Bin Chen
A B Cosimi
Tatsuo Kawai
James Allan
Tetsu Oura
P2860cites workCombined Bone Marrow and Kidney Transplantation for the Induction of Specific ToleranceQ26745435
Normal human kidney HLA-DR-expressing renal microvascular endothelial cells: characterization, isolation, and regulation of MHC class II expressionQ31139922
Effect of tolerance versus chronic immunosuppression protocols on the quality of life of kidney transplant recipientsQ33468225
HLA-mismatched renal transplantation without maintenance immunosuppressionQ33640791
Alefacept promotes immunosuppression-free renal allograft survival in nonhuman primates via depletion of recipient memory T cellsQ33881015
Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression.Q34496604
Use of CTLA4Ig for induction of mixed chimerism and renal allograft tolerance in nonhuman primatesQ34536503
Strategies to improve long-term outcomes after renal transplantationQ34539775
Cardiovascular toxicities of immunosuppressive agentsQ34976738
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primatesQ34991139
Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts.Q35083894
Heterologous immunity provides a potent barrier to transplantation toleranceQ35095576
Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal diseaseQ35596427
Repeated Injections of IL-2 Break Renal Allograft Tolerance Induced via Mixed Hematopoietic Chimerism in MonkeysQ36304389
HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamideQ37078261
Kidney Versus Islet Allograft Survival After Induction of Mixed Chimerism With Combined Donor Bone Marrow TransplantationQ37098988
Induced regulatory T cells in allograft tolerance via transient mixed chimerismQ37109198
Human effector memory CD4+ T cells directly recognize allogeneic endothelial cells in vitro and in vivo.Q51971439
Risk of neoplasia in renal transplant patients.Q52870351
Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimenQ72051514
Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeysQ72487030
Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft toleranceQ73299841
Thromboembolic complications after treatment with monoclonal antibody against CD40 ligandQ73401367
Improved graft survival after renal transplantation in the United States, 1988 to 1996Q73502580
Effect of mixed hematopoietic chimerism on cardiac allograft survival in cynomolgus monkeysQ74365678
A randomized, double-blinded comparison of Thymoglobulin versus Atgam for induction immunosuppressive therapy in adult renal transplant recipientsQ77378215
Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerismQ78237930
Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic miceQ79445122
Infection frequency and profile in different age groups of kidney transplant recipientsQ79775604
CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primatesQ80444346
Dialysis-dependent renal failure at diagnosis continues to be associated with very poor outcome in multiple myelomaQ87399995
P577publication date2017-11-21
P1433published inHuman ImmunologyQ15709955
P1476titlePreclinical and clinical studies for transplant tolerance via the mixed chimerism approach

Reverse relations

cites work (P2860)
Q97636517Cell therapy can enable minimization of immunosuppression
Q91604362Ex vivo perfusion-based engraftment of genetically engineered cell sensors into transplantable organs
Q90185646Impact of infection on transplantation tolerance
Q90955751Strategies to achieve immune tolerance in allogeneic solid organ transplantation

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