Revolution stalled

scientific article published in October 2012

Revolution stalled is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1126/SCITRANSLMED.3003142
P698PubMed publication ID23052291
P5875ResearchGate publication ID232229011

P2093author name stringSteven E Hyman
P2860cites workPrevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey ReplicationQ22253031
Shank3 mutant mice display autistic-like behaviours and striatal dysfunctionQ24597501
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcriptionQ24605428
Modelling schizophrenia using human induced pluripotent stem cellsQ24633007
Effectiveness of antipsychotic drugs in patients with chronic schizophreniaQ28273164
Effectiveness of adjunctive antidepressant treatment for bipolar depressionQ28295408
Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D reportQ29615999
A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depressionQ29617914
Optogenetics in neural systemsQ29618164
Animal models of neuropsychiatric disordersQ29619899
Human-specific transcriptional networks in the brainQ30539579
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.Q33398247
Genetic architectures of psychiatric disorders: the emerging picture and its implicationsQ33949729
Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazineQ34048732
Trends in risks associated with new drug development: success rates for investigational drugsQ34096792
Animal models of neuropsychiatric disorders.Q34158236
Effect of psychotropic drugs on the uptake of H3-norepinephrine by tissuesQ34648871
Toward Fulfilling the Promise of Molecular Medicine in Fragile X SyndromeQ34999452
Medicine. What are the right targets for psychopharmacology?Q35047348
Can neuroscience be integrated into the DSM-V?Q36912772
Developing treatments for impaired cognition in schizophreniaQ37969402
Functional consequences of mutations in postsynaptic scaffolding proteins and relevance to psychiatric disorders.Q38006055
Learned HelplessnessQ39921518
Novartis to shut brain research facilityQ48787775
Is pharma running out of brainy ideas?Q51847289
P433issue155
P407language of work or nameEnglishQ1860
P304page(s)155cm11
P577publication date2012-10-01
P1433published inScience Translational MedicineQ1573955
P1476titleRevolution stalled
P478volume4

Reverse relations

cites work (P2860)
Q54986717A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits.
Q92447843An Innovative Disease-Drug-Trial Framework to Guide Binge Eating Disorder Drug Development: A Case Study for Topiramate
Q50101264Animal Models in Translational Research: Rosetta Stone or Stumbling Block?
Q91997345Animal models of PTSD: a challenge to be met
Q36772243Assessment of adverse effects of neurotropic drugs in monkeys with the "drug effects on the nervous system" (DENS) scale
Q57255770Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism
Q48271076Back to basics: luring industry back into neuroscience
Q91773699Brain Banks Spur New Frontiers in Neuropsychiatric Research and Strategies for Analysis and Validation
Q91867564Can N-Methyl-D-Aspartate Receptor Hypofunction in Schizophrenia Be Localized to an Individual Cell Type?
Q92523500Can prospective systematic reviews of animal studies improve clinical translation?
Q38392369Can proteomics-based diagnostics aid clinical psychiatry?
Q35802879Challenges in understanding psychiatric disorders and developing therapeutics: a role for zebrafish.
Q40237566Changing the mindset in life sciences toward translation: a consensus
Q26830079Circadian rhythms and mood: opportunities for multi-level analyses in genomics and neuroscience: circadian rhythm dysregulation in mood disorders provides clues to the brain's organizing principles, and a touchstone for genomics and neuroscience
Q92065355Clinical Trials in Alzheimer's Disease: A Hurdle in the Path of Remedy
Q35195189Closed-loop rehabilitation of age-related cognitive disorders
Q50599089Commentary: Insights from across diagnostic boundaries: ADHD in the RDoC era--a commentary on Scerif and Baker (2015).
Q47239298Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity
Q90597805Developing neuroscience-based treatments for alcohol addiction: A matter of choice?
Q30399543Don't stress about CRF: assessing the translational failures of CRF1antagonists
Q95579834Drug discovery in psychopharmacology: from 2D models to cerebral organoids
Q46302488Drug discovery: Zebrafish uncover novel antipsychotics
Q37310536Editorial (Thematic Selection: Inflammatory and Immune Responses in Depression).
Q38080006Future viable models of psychiatry drug discovery in pharma
Q39682696Gene-set analysis based on the pharmacological profiles of drugs to identify repurposing opportunities in schizophrenia.
Q26859474Genome-scale neurogenetics: methodology and meaning
Q38967700Genome-wide association study of lymphoblast cell viability after clozapine exposure.
Q29396464Human genome-guided identification of memory-modulating drugs
Q30363008Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers
Q27008349Improving and accelerating drug development for nervous system disorders
Q48721089Industry withdrawal from psychiatric medication development
Q42623009Intermittent Access to Ethanol Induces Escalated Alcohol Consumption in Primates
Q48176769Mental health: depression needs large human-genetics studies
Q38960878Models of neuromodulation for computational psychiatry
Q30432026Mouse models of gene-environment interactions in schizophrenia
Q38110960Neural stem cells as tools for drug discovery: novel platforms and approaches
Q50480596Neurobiology: learning from marmosets.
Q35148225Neurofeedback and networks of depression
Q38978555Neuroscience and the future for mental health?
Q36760914New Hippocampal Neurons Mature Rapidly in Response to Ketamine But Are Not Required for Its Acute Antidepressant Effects on Neophagia in Rats.
Q37607004New paradigms for treatment-resistant depression
Q51438275Nociceptin Receptor as a Target to Treat Alcohol Use Disorder: Challenges in Advancing Medications Development.
Q38826903Opportunities and challenges in modeling human brain disorders in transgenic primates
Q45233687Opposing roles of primate areas 25 and 32 and their putative rodent homologs in the regulation of negative emotion
Q46310313Organoid technology for brain and therapeutics research
Q90600109Oxytocin Enhances an Amygdala Circuit Associated With Negative Symptoms in Schizophrenia: A Single-Dose, Placebo-Controlled, Crossover, Randomized Control Trial
Q38683538Oxytocin effects in schizophrenia: Reconciling mixed findings and moving forward
Q35107323Pathway analyses implicate glial cells in schizophrenia
Q36594394Pathways to new drug discovery in neuropsychiatry
Q37255533Pharmaceutical Innovation in the Treatment of Schizophrenia and Mental Disorders Compared with Other Diseases
Q36109996PhenoPredict: A disease phenome-wide drug repositioning approach towards schizophrenia drug discovery
Q89983282Post-translational protein modifications in schizophrenia
Q38268791Postdependent state in rats as a model for medication development in alcoholism
Q90029576Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials
Q40965698Psychiatric drug development: diagnosing a crisis
Q44884838Public-private partnerships to revitalize psychiatric drug discovery
Q90214267Redirecting the revolution: new developments in drug development for psychiatry
Q57316758Rediscovering the value of families for psychiatric genetics research
Q90427486Reduced GluN1 in mouse dentate gyrus is associated with CA3 hyperactivity and psychosis-like behaviors
Q57475754Resilience priming: Translational models for understanding resiliency and adaptation to early life adversity
Q37379464Revitalizing psychiatric therapeutics
Q40446474Schizophrenia research in 2013: are we making progress?
Q91794197Sleep as a translationally-relevant endpoint in studies of autism spectrum disorder (ASD)
Q91610081Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept
Q30366697Targeting Functional Biomarkers in Schizophrenia with Neuroimaging.
Q28074803The "Vulnerability" of Psychiatric Research Participants: Why This Research Ethics Concept Needs to Be Revisited
Q48305886The Corticotropin Releasing Factor Receptor 1 in Alcohol Use Disorder: Still a Valid Drug Target?
Q37666098The Genetics-Driven Revival in Neuropsychiatric Drug Development.
Q35754731The NIMH experimental medicine initiative
Q38848288The Need for Treatment Responsive Translational Biomarkers in Alcoholism Research
Q58556540The Role of Precision Medicine in Child Psychiatry: What Can We Expect and When?
Q39423428The current development of CNS drug research
Q50418526The daunting polygenicity of mental illness: making a new map.
Q36677600The diminished pipeline for medications to treat mental health and substance use disorders
Q47601684The microbiome as a novel paradigm in studying stress and mental health.
Q28236333The neurocircuitry of illicit psychostimulant addiction: acute and chronic effects in humans
Q35190746The place of psychotherapy in contemporary psychiatry
Q38629117The promise and pitfalls of intranasally administering psychopharmacological agents for the treatment of psychiatric disorders
Q38802467The promises and challenges of human brain organoids as models of neuropsychiatric disease
Q90285681The research domain criteria framework in drug discovery for neuropsychiatric diseases: focus on negative valence
Q38992286The road to precision psychiatry: translating genetics into disease mechanisms.
Q50623386The unconscionable gap between what we know and what we do.
Q91516614Translating the promise of 5HT4 receptor agonists for the treatment of depression
Q37275071Translation: screening for novel therapeutics with disease-relevant cell types derived from human stem cell models
Q37171853Translational Assessment of Reward and Motivational Deficits in Psychiatric Disorders
Q38370696Translational psychiatry--light at the end of the tunnel.
Q47561695Tranylcypromine Causes Neurotoxicity and Represses BHC110/LSD1 in Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids Model
Q37384323Twenty-five years of progress: the view from NIMH and NINDS
Q28083512What Have Mass Spectrometry-Based Proteomics and Metabolomics (Not) Taught Us about Psychiatric Disorders?
Q48800850White matter injuries induced by MK-801 in a mouse model of schizophrenia based on NMDA antagonism
Q92217485Why we need nonhuman primates to study the role of ventromedial prefrontal cortex in the regulation of threat- and reward-elicited responses
Q30369007Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds.
Q30773565σ1 receptor ligands control a switch between passive and active threat responses

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