NMDA and non-NMDA receptor antagonists protect against excitotoxic injury in the rat spinal cord

scientific article published in May 1997

NMDA and non-NMDA receptor antagonists protect against excitotoxic injury in the rat spinal cord is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-8993(97)00137-6
P698PubMed publication ID9187327

P2093author name stringLiu S
Yezierski RP
Ruenes GL
P2860cites workA new type of glutamate receptor linked to inositol phospholipid metabolismQ28282769
Protective effect of the NMDA antagonist MK-801 on photochemically induced spinal lesions in the ratQ30997069
Excitotoxic cell deathQ34245367
Transient spinal ischemia in rat: characterization of spinal cord blood flow, extracellular amino acid release, and concurrent histopathological damageQ36732406
Characterization of photochemically induced spinal cord injury in the rat by light and electron microscopyQ36752028
Pharmacological and functional characteristics of metabotropic excitatory amino acid receptorsQ37566538
Excitatory amino acid receptors in the brain: membrane binding and receptor autoradiographic approachesQ37576595
The role of glutamate neurotoxicity in hypoxic-ischemic neuronal deathQ37585239
Excitatory amino acids and synaptic transmission: the evidence for a physiological functionQ37588602
Excitatory amino acid neurotoxicity and neurodegenerative diseaseQ37989602
Glutamate and the pathophysiology of hypoxic--ischemic brain damageQ38161694
The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous systemQ38272501
The physiology of excitatory amino acids in the vertebrate central nervous systemQ39462515
Pain following spinal cord injury: the clinical problem and experimental studiesQ40917755
Effect of kynurenate on functional deficits resulting from traumatic spinal cord injuryQ41099555
Spinal cord ischemia-induced elevation of amino acids: extracellular measurement with microdialysisQ41175290
Alteration in extracellular amino acids after traumatic spinal cord injuryQ41223676
A potential role for excitotoxins in the pathophysiology of spinal cord injuryQ41336337
Ionic dependence of glutamate neurotoxicityQ41343328
Neuronal damage following intraspinal injection of a nitric oxide synthase inhibitor in the rat.Q42522499
Effects of NMDA receptor antagonists following spinal ischemia in the rabbitQ43844073
Evidence that local non-NMDA receptors contribute to functional deficits in contusive spinal cord injuryQ44176716
Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damageQ45181343
Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neuronesQ45263360
Neuroprotective effect of MK-801 and U-50488H after contusive spinal cord injuryQ46862766
The mechanosensitivity of spinal sensory neurons following intraspinal injections of quisqualic acid in the rat.Q48249793
Quisqualic acid-induced neurotoxicity is protected by NMDA and non-NMDA receptor antagonistsQ48443653
The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injuryQ48480880
NBQX, an AMPA antagonist, reduces glutamate-mediated brain edemaQ48525869
Quisqualate‐Stimulated Phosphatidylinositol Breakdown in Rat Cerebellar MembranesQ48545192
Glutamate Toxicity: An Experimental and Theoretical AnalysisQ48551781
Vascular changes in the spinal cord in N-methyl-D-aspartate-induced excitotoxicity: morphological and permeability studiesQ48581349
Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cordQ48722828
Neurotoxic effects of excitatory amino acids in the mouse spinal cord: quisqualate and kainate but not N-methyl-D-aspartate induce permanent neural damageQ48880347
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemiaQ49105194
The role of excitatory amino acids and NMDA receptors in traumatic brain injuryQ69370501
Quisqualate neurotoxicity: a delayed, CNQX-sensitive process triggered by a CNQX-insensitive mechanism in young rat hippocampal slicesQ69371833
Calcium dependency of N-methyl-D-aspartate toxicity in slices from the immature rat hippocampusQ69556030
Neuronal degeneration and spinal cavitation following intraspinal injections of quisqualic acid in the ratQ72333509
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectexcitotoxicityQ901117
P304page(s)160-167
P577publication date1997-05-01
P1433published inBrain ResearchQ4955782
P1476titleNMDA and non-NMDA receptor antagonists protect against excitotoxic injury in the rat spinal cord
P478volume756

Reverse relations

cites work (P2860)
Q44893940AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo.
Q37252957Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury
Q79489612Astroglia-mediated effects of uric acid to protect spinal cord neurons from glutamate toxicity
Q39174919CCR5 blockade promotes M2 macrophage activation and improves locomotor recovery after spinal cord injury in mice
Q41093883Central Pain from Excitotoxic Spinal Cord Injury Induced by Intraspinal NMDA Injection: A Pilot Study
Q40440411Comparison of the spinal neuropathic pain induced by intraspinal injection of N-methyl-d-aspartate and quisquate in rats
Q44658683Conditions affecting the onset, severity, and progression of a spontaneous pain-like behavior after excitotoxic spinal cord injury
Q43981146DNA microarray analysis of the contused spinal cord: effect of NMDA receptor inhibition
Q73058913Diffusion-weighted MR imaging in a rat model of syringomyelia after excitotoxic spinal cord injury
Q48850105Effects of sacrocaudal spinal cord transection and transplantation of fetal spinal tissue on withdrawal reflexes of the tail
Q41205010Gliopathy ensures persistent inflammation and chronic pain after spinal cord injury
Q45116227Glutamate and its receptors in the pathophysiology of brain and spinal cord injuries
Q48266710MicroRNA-155 Deficiency Suppresses Th17 Cell Differentiation and Improves Locomotor Recovery after Spinal Cord Injury
Q44567424N-methyl-D-aspartate receptor subunit expression and phosphorylation following excitotoxic spinal cord injury in rats
Q44753973Neuroprotective effects of nicotinamide after experimental spinal cord injury
Q73029455Neurotoxicity of glutamate at the concentration released upon spinal cord injury
Q34581480Non-surgical management of spinal cord injury
Q44332581Opioid peptide messenger RNA expression is increased at spinal and supraspinal levels following excitotoxic spinal cord injury
Q42414570PI3K mediated activation of GSK-3β reduces at-level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias
Q34094124Pain following spinal cord injury: pathophysiology and central mechanisms
Q38234624Receptor for advanced glycation end products (RAGE) and its ligands: focus on spinal cord injury
Q40767258Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury
Q48000851Retracing your footsteps: developmental insights to spinal network plasticity following injury.
Q36056763Review of the history and current status of cell-transplant approaches for the management of neuropathic pain
Q73930249Riluzole improves measures of oxidative stress following traumatic spinal cord injury
Q50522867Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury.
Q44262077The influence of MK-801 on the hippocampal free arachidonic acid level and Na+,K+-ATPase activity in global cerebral ischemia-exposed rats.
Q43664469The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury

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