Estradiol attenuates spinal cord injury-related central pain by decreasing glutamate levels in thalamic VPL nucleus in male rats.

scientific article published on 31 May 2014

Estradiol attenuates spinal cord injury-related central pain by decreasing glutamate levels in thalamic VPL nucleus in male rats. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11011-014-9570-Z
P698PubMed publication ID24879046
P5875ResearchGate publication ID262783426

P50authorAlireza GhanbariQ81555194
P2093author name stringMasoumeh Jorjani
Reza Zahed
Asieh Naderi
Razieh Samandari
Ali Reza Asgari
P2860cites workThe NMDA antagonist MK-801 induces hyperalgesia and increases CSF excitatory amino acids in rats: reversal by guanosineQ46317480
Bilateral hyperexcitability of thalamic VPL neurons following unilateral spinal injury in rats.Q46351844
Regulation of glutamate transporter GLAST and GLT-1 expression in astrocytes by estrogen.Q46493115
Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonistQ46535923
Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in ratsQ46676371
Effect of 17beta-estradiol on functional outcome, release of cytokines, astrocyte reactivity and inflammatory spreading after spinal cord injury in male ratsQ46721526
Estradiol and progesterone differentially regulate formalin-induced nociception in ovariectomized female ratsQ46780950
Chronic spinal cord injury induced changes in the responses of thalamic neuronsQ46788047
Metabolic changes in the thalamus after spinal cord injury followed by proton MR spectroscopyQ46791831
Estradiol attenuates spinal cord injury-induced pain by suppressing microglial activation in thalamic VPL nuclei of rats.Q48158274
The effects of estradiol on estrogen receptor and glutamate transporter expression in organotypic hippocampal cultures exposed to oxygen--glucose deprivationQ48507601
The effects of estrogen and progesterone on blood glutamate levels: evidence from changes of blood glutamate levels during the menstrual cycle in women.Q51535524
Neuropathic pain after traumatic spinal cord injury--relations to gender, spinal level, completeness, and age at the time of injury.Q53286735
Steroid hormones protect spinal cord neurons from glutamate toxicityQ72232866
An improved method for assessing mechanical allodynia in the ratQ73289147
Modulation of nociceptive transmission by NMDA/glycine site receptor in the ventroposterolateral nucleus of the thalamusQ73427511
Geometry and charge determine pharmacological effects of steroids on N-methyl-D-aspartate receptor-induced Ca(2+) accumulation and cell deathQ73929988
Neurochemical changes after morphine, dizocilpine or riluzole in the ventral posterolateral thalamic nuclei of rats with hyperalgesiaQ74254239
An estrogen receptor-beta agonist is active in models of inflammatory and chemical-induced painQ79286110
Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injuryQ81084350
Mechanisms of chronic central neuropathic pain after spinal cord injuryQ24655280
Role of spinal cord glutamate transporter during normal sensory transmission and pathological pain statesQ24812394
Quantitative assessment of tactile allodynia in the rat pawQ29617366
Estradiol treatment prevents injury induced enhancement in spinal cord dynorphin expressionQ30428238
Sex and hormonal variations in the development of at-level allodynia in a rat chronic spinal cord injury model.Q30431772
Extracellular glutamate, aspartate and arginine increase in the ventral posterolateral thalamic nucleus during nociceptive stimulationQ30778937
Spinal cord injury causes a wide-spread, persistent loss of Kir4.1 and glutamate transporter 1: benefit of 17 beta-oestradiol treatmentQ33773510
Impaired glial glutamate uptake induces extrasynaptic glutamate spillover in the spinal sensory synapses of neuropathic ratsQ33841330
Estrogen effects on pain sensitivity and neuropeptide expression in rat sensory neuronsQ33912929
Neuroprotective effects of estrogens: potential mechanisms of actionQ33922344
In vivo microdialysis for nonapeptides in rat brain--a practical guideQ34132293
17beta-estradiol rapidly enhances bradykinin signaling in primary sensory neurons in vitro and in vivoQ34214630
Neurotensin modulation of acetylcholine, GABA, and aspartate release from rat prefrontal cortex studied in vivo with microdialysisQ34812081
Estrogen modulation of peripheral pain signal transduction: involvement of P2X(3) receptorsQ34868452
Restoring function after spinal cord injuryQ35152019
Estrogen as a neuroprotective agent in the treatment of spinal cord injuryQ35174562
Low dose estrogen prevents neuronal degeneration and microglial reactivity in an acute model of spinal cord injury: effect of dosing, route of administration, and therapy delayQ35182059
Pronociceptive and antinociceptive effects of estradiol through endogenous opioid neurotransmission in womenQ35658836
Neuropathic pain: mechanisms and treatments.Q36329153
Neuroprotection by ovarian hormones in animal models of neurological diseaseQ36511922
17β-estradiol confers protection after traumatic brain injury in the rat and involves activation of G protein-coupled estrogen receptor 1.Q37115243
Homeostasis of glutamate in brain fluids: an accelerated brain-to-blood efflux of excess glutamate is produced by blood glutamate scavenging and offers protection from neuropathologiesQ37142758
Management of neuropathic pain following spinal cord injury: now and in the futureQ37323333
Spinal cord injury pain: spinal and supraspinal mechanisms.Q37522135
GABA and central neuropathic pain following spinal cord injuryQ37826940
17beta-estradiol rescues spinal motoneurons from AMPA-induced toxicity: a role for glial cellsQ40422759
Interrelationships of neurochemicals, estrogen, and recurring headacheQ40936832
Maladaptive homeostatic plasticity in a rodent model of central pain syndrome: thalamic hyperexcitability after spinothalamic tract lesionsQ41862815
Activation of p38 MAP kinase is involved in central neuropathic pain following spinal cord injuryQ41869178
Gene transfer of GLT-1, a glial glutamate transporter, into the spinal cord by recombinant adenovirus attenuates inflammatory and neuropathic pain in ratsQ41949585
Role of microglia and astrocyte in central pain syndrome following electrolytic lesion at the spinothalamic tract in ratsQ42654743
Molecular analysis of estrogen induction of preproenkephalin gene expression and its modulation by thyroid hormonesQ43678312
17Beta-estradiol blocks NMDA-induced increases in regional cerebral O(2) consumptionQ44148974
In vivo microdialysis of glutamate in ventroposterolateral nucleus of thalamus following electrolytic lesion of spinothalamic tract in rats.Q45906638
P433issue3
P304page(s)763-770
P577publication date2014-05-31
P1433published inMetabolic Brain DiseaseQ15764352
P1476titleEstradiol attenuates spinal cord injury-related central pain by decreasing glutamate levels in thalamic VPL nucleus in male rats
P478volume29

Reverse relations

cites work (P2860)
Q48204540Ablation of IB4 non-peptidergic afferents in the rat facet joint prevents injury-induced pain and thalamic hyperexcitability via supraspinal glutamate transporters
Q57031032Conotoxin MVIIA improves cell viability and antioxidant system after spinal cord injury in rats
Q49721980Daily Fluctuations of Progesterone and Testosterone Are Associated With Fibromyalgia Pain Severity.
Q27004604Diabetic neuropathic pain: Physiopathology and treatment
Q59360915G protein functions in thalamic neurons to decrease orofacial nociceptive response
Q36505520Genes in the GABA Pathway Increase in the Lateral Thalamus of Sprague-Dawley Rats During the Proestrus/Estrus Phase
Q50437082Red nucleus glutamate facilitates neuropathic allodynia induced by spared nerve injury through non-NMDA and metabotropic glutamate receptors
Q45026393Role for the Ventral Posterior Medial/Posterior Lateral Thalamus and Anterior Cingulate Cortex in Affective/Motivation Pain Induced by Varicella Zoster Virus
Q92967472Sex Differences and Role of Gonadal Hormones on Glutamate LevelAfter Spinal Cord Injury in Rats: A Microdialysis Study

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