Design of a specific activator for skeletal muscle sodium channels uncovers channel architecture

scientific article published on 8 August 2007

Design of a specific activator for skeletal muscle sodium channels uncovers channel architecture is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M704651200
P698PubMed publication ID17686768
P5875ResearchGate publication ID6152349

P2093author name stringDalia Gordon
Michael Gurevitz
Nitza Ilan
Walter Stühmer
Lior Cohen
Maya Gur
P2860cites workCharge movement associated with the opening and closing of the activation gates of the Na channelsQ24649965
Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channelsQ27617567
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Crystal structure of a mammalian voltage-dependent Shaker family K+ channelQ28260421
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Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II.Q34479240
Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.Q34526433
An expanding view for the molecular basis of familial periodic paralysisQ34738564
Skeletal muscle channelopathiesQ34990898
Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.Q35001630
Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayerQ35127506
Voltage-sensor sodium channel mutations cause hypokalemic periodic paralysis type 2 by enhanced inactivation and reduced currentQ35208537
Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3.Q40287589
Enhanced inactivation and pH sensitivity of Na(+) channel mutations causing hypokalaemic periodic paralysis type II.Q40742646
Interaction of scorpion alpha-toxins with cardiac sodium channels: binding properties and enhancement of slow inactivationQ41949009
Hypokalaemic periodic paralysis type 2 caused by mutations at codon 672 in the muscle sodium channel gene SCN4A.Q43608348
Voltage sensor of Kv1.2: structural basis of electromechanical couplingQ46588794
Effect of depolarization on binding kinetics of scorpion alpha-toxin highlights conformational changes of rat brain sodium channelsQ48703447
Gating pore current in an inherited ion channelopathyQ48799799
Effects of Tityus serrulatus scorpion toxin gamma on voltage-gated Na+ channelsQ48962330
Modulation of the skeletal muscle sodium channel alpha-subunit by the beta 1-subunitQ49124231
Common features in the functional surface of scorpion beta-toxins and elements that confer specificity for insect and mammalian voltage-gated sodium channels.Q51821558
Dissection of the functional surface of an anti-insect excitatory toxin illuminates a putative "hot spot" common to all scorpion beta-toxins affecting Na+ channels.Q52642236
P433issue40
P407language of work or nameEnglishQ1860
P304page(s)29424-29430
P577publication date2007-08-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleDesign of a specific activator for skeletal muscle sodium channels uncovers channel architecture
P478volume282