Can leptin-derived sequence-modified nanoparticles be suitable tools for brain delivery?

scientific article published on 30 September 2011

Can leptin-derived sequence-modified nanoparticles be suitable tools for brain delivery? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2217/NNM.11.98
P698PubMed publication ID21957863
P5875ResearchGate publication ID51680219

P50authorAnna Valeria VergoniQ59198170
Barbara RuoziQ39549923
Giovanni TosiQ39549958
Flavio ForniQ39550000
Maria Angela VandelliQ39550040
Anna FerrariQ39803399
P2093author name stringFrancesco Rivasi
Luca Badiali
Lucia Bondioli
P2860cites workUbiquitylation of leptin receptor OB-Ra regulates its clathrin-mediated endocytosisQ24304963
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Identification and expression cloning of a leptin receptor, OB-RQ29620255
Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain deliveryQ33955046
Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteinsQ34035426
TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugsQ34818171
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Influence of surface-modifying surfactants on the pharmacokinetic behavior of 14C-poly (methylmethacrylate) nanoparticles in experimental tumor models.Q52960129
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Modulation of nucleic acid structure by ligand binding: induction of a DNA.RNA.DNA hybrid triplex by DAPI intercalation.Q38345373
Near complete rescue of experimental Parkinson's disease with intravenous, non-viral GDNF gene therapyQ39902228
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Convergent trafficking pattern of leptin after endocytosis mediated by ObRa-ObRdQ40166509
Sialic acid and glycopeptides conjugated PLGA nanoparticles for central nervous system targeting: In vivo pharmacological evidence and biodistribution.Q43118634
Leptin-derived peptide, a targeting ligand for mouse brain-derived endothelial cells via macropinocytosis.Q43137017
A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection.Q43248430
Surface modification of poly(lactic acid) nanoparticles by covalent attachment of thiol groups by means of three methodsQ44277706
Brain uptake of thiamine-coated nanoparticlesQ44673525
Poly(lactic acid) nanoparticles labeled with biologically active Neutravidin for active targetingQ45080918
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Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling.Q46620831
Targeting of daunomycin using biotinylated immunoliposomes: pharmacokinetics, tissue distribution and in vitro pharmacological effectsQ46731833
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Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123.Q48096517
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A leptin derived 30-amino-acid peptide modified pegylated poly-L-lysine dendrigraft for brain targeted gene deliveryQ48240744
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Regional localization of specific [125I]leptin binding sites in rat forebrainQ48462371
Biodistribution of polysorbate 80-coated doxorubicin-loaded [14C]-poly(butyl cyanoacrylate) nanoparticles after intravenous administration to glioblastoma-bearing ratsQ48587255
Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat.Q48606965
Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neuronesQ48706032
The identification of leptin-derived peptides that are taken up by the brainQ48734007
Peptide-derivatized biodegradable nanoparticles able to cross the blood-brain barrierQ48774664
Effects of peripheral 5-HT2 and 5-HT3 receptor agonists on food intake in food-deprived and 2-deoxy-D-glucose-treated ratsQ48778910
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Leptin access into the brain: a saturated transport mechanism in obesityQ50118046
P433issue3
P921main subjectnanoparticleQ61231
P304page(s)365-382
P577publication date2011-09-30
P1433published inNanomedicineQ15817508
P1476titleCan leptin-derived sequence-modified nanoparticles be suitable tools for brain delivery?
P478volume7

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cites work (P2860)
Q39164804Blood-brain barrier transport machineries and targeted therapy of brain diseases.
Q49102381Brain targeting with polymeric nanoparticles: which administration route should we take?
Q39438422Brain-targeted polymeric nanoparticles: in vivo evidence of different routes of administration in rodents
Q40295370Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice
Q26850868Enabling nanomaterial, nanofabrication and cellular technologies for nanoneuromedicines
Q36307467Nano-enabled delivery of diverse payloads across complex biological barriers
Q38038895Nanobiotechnology-based strategies for crossing the blood-brain barrier
Q45897427Nanotechnology-based strategies for the diagnosis and treatment of intracranial neoplasms
Q39154878Novel functionalization strategies of polymeric nanoparticles as carriers for brain medications
Q48111341PLGA Nanoparticles Loaded Cerebrolysin: Studies on Their Preparation and Investigation of the Effect of Storage and Serum Stability with Reference to Traumatic Brain Injury
Q26778701Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer
Q26751294Systemic delivery to central nervous system by engineered PLGA nanoparticles

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