Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C.

scientific article published in October 1996

Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF00128958
P2888exact matchhttps://scigraph.springernature.com/pub.10.1007/bf00128958
P698PubMed publication ID8871536

P2093author name stringV W Yong
J H Uhm
J G Villemure
N P Dooley
P2860cites workInhibition of growth of established human glioma cell lines by modulators of the protein kinase-C system.Q55484376
Membrane proteases in focusQ59052655
Neutral proteinases of human mononuclear phagocytes. Cellular differentiation markedly alters cell phenotype for serine proteinases, metalloproteinases, and tissue inhibitor of metalloproteinasesQ68190931
The pattern of metalloproteinase expression by corneal fibroblasts is altered by passage in cell cultureQ68493823
Gelatinases of murine metastatic tumor cellsQ69325885
Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-betaQ69326294
Effects of 12-O-tetradecanoylphorbol-13-acetate on adhesiveness and lung-colonizing ability of Lewis lung carcinoma cellsQ69988354
Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinomaQ72253840
Antibody to rabbit macrophage type V collagenase/gelatinase and its use to further characterize the enzymeQ72389147
Transforming growth factor beta 1 regulation of metalloproteinase production in cultured human cervical epithelial cellsQ72785644
Regulation of tissue inhibitor of matrix metalloproteinase expressionQ72853147
A matrix metalloproteinase expressed on the surface of invasive tumour cellsQ24312733
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogeneQ29618347
Adhesion molecules and malignant gliomas: implications for tumorigenesisQ36006737
Plasminogen activator and collagenase production by cultured capillary endothelial cellsQ36209178
Glioblastoma infiltration into central nervous system tissue in vitro: involvement of a metalloproteaseQ36220992
Cloning and regulation of rat tissue inhibitor of metalloproteinases-2 in osteoblastic cellsQ36752257
Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasisQ37483919
Protease inhibitors implicate metalloendoprotease in synaptic transmission at the mammalian neuromuscular junctionQ37616838
Brain tumor epidemiology, growth, and invasionQ37848135
Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis.Q38190315
Biochemical interactions of tumor cells with the basement membraneQ39503917
Matrix metalloproteinase gene expressionQ40642356
Metalloproteinase domain structure, cellular invasion and metastasisQ40764344
Cell-adhesion molecules and metalloproteinases: a linked role in tumour cell invasivenessQ40764352
The potential of protein kinase C as a target for anticancer treatmentQ40815216
Biology and biochemistry of proteinases in tumor invasion.Q40868702
Protein kinase C: a novel target for inhibiting gastric cancer cell invasionQ41085730
Possible involvement of Ca2+ mobilization and protein kinase C activation in the induction of spontaneous metastasis by mouse mammary adenocarcinoma cellsQ41260804
Cyclic AMP-regulated synthesis of the tissue inhibitors of metalloproteinases suppresses the invasive potential of the human fibrosarcoma cell line HT1080.Q41328328
Expression of timp-1, timp-2, 72-kda and 92-kda type-iv collagenase transcripts in human astrocytoma cell-lines - correlation with astrocytoma cell invasivenessQ41351721
Monoclonal antibodies to human MMP-9.Q41442903
Increase in urokinase plasminogen activator mRNA synthesis in human carcinoma cells is a primary effect of the potent tumor promoter, phorbol myristate acetateQ41503011
TPA-enhanced invasion of Matrigel associated with augmentation of cell motility but not metalloproteinase activity in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1.Q41509771
Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. A comparison between staurosporine and tamoxifenQ41528688
The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion.Q41542149
Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel modelQ41586807
Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase CQ41600478
The effect of tumor necrosis factor-α on human malignant glial cellsQ41633889
Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell linesQ41651909
Tumor Cell Invasion Inhibited by TIMP-2Q41679983
Inhibition of protein kinase C by calphostin C is light-dependentQ41687741
A metalloproteinase, capable of destroying cultured brain tissue isolated from rat glioma cellsQ41691814
Inhibition of invasion of invasive human bladder carcinoma cells by protein kinase C inhibitor staurosporineQ41714472
Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cellsQ41737236
Differential proliferative response of human and mouse astrocytes to gamma-interferonQ42457396
Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitroQ42468714
A rapid in vitro assay for quantitating the invasive potential of tumor cellsQ42807739
Cultured human glial and glioma cells.Q42823441
Induction of proto-oncogene JUN/AP-1 by serum and TPA.Q43487125
Regulation of collagenase and collagenase mRNA production in early- and late-passage human diploid fibroblastsQ44234904
Characterization and Identification of Proteinases and Proteinase Inhibitors Synthesized by Temporomandibular Joint Disc CellsQ46352323
Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumorsQ48091109
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinomaQ48241087
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumorsQ48284379
Glioma cell interactions with fetal rat brain aggregates in vitro and with brain tissue in vivoQ48315375
Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.Q48376448
Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and prostromelysin exceeds expression of proteolytic activityQ48376454
Serum proteolytic activity during the growth of C6 astrocytomaQ48428986
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.Q54425576
Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells.Q55481909
P433issue5
P304page(s)421-433
P577publication date1996-10-01
P1433published inClinical & Experimental MetastasisQ13470030
P1476titleGlioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C.
P478volume14

Reverse relations

cites work (P2860)
Q38009800A complete compilation of matrix metalloproteinase expression in human malignant gliomas.
Q45009039Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP.
Q40980125Astrocytoma cell interaction with elastin substrates: implications for astrocytoma invasive potential
Q36509566Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide
Q39817583Characterization of the serum metabolome following radiation treatment in patients with high-grade gliomas
Q33743513Comparative expression pattern of Matrix-Metalloproteinases in human glioblastoma cell-lines and primary cultures.
Q36715291Correlations of polymorphisms in matrix metalloproteinase-1, -2, and -7 promoters to susceptibility to malignant gliomas
Q41991420Differential expression and localization of TIMP-1 and TIMP-4 in human gliomas
Q40830443Discoidin domain receptor 1 (DDR1), a promising biomarker, induces epithelial to mesenchymal transition in renal cancer cells
Q40360371Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2.
Q34332239Envelope gene-mediated neurovirulence in feline immunodeficiency virus infection: induction of matrix metalloproteinases and neuronal injury
Q40645479Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade.
Q42048997Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors
Q55475249Expression of emmprin (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas.
Q55475897Expression of matrix metalloproteinase-2 in glial and neuronal tumor cell lines: inverse correlation with proliferation rate.
Q40979862Expression of matrix metalloproteinases in human glioma cell lines in the presence of IL-10.
Q24649857Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas
Q55475300Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts.
Q32061182HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors
Q28206393Hyaluronate receptors mediating glioma cell migration and proliferation
Q48457559Induction of matrix metalloproteinase-9 requires a polymerized actin cytoskeleton in human malignant glioma cells.
Q39938155Inflammatory cytokine modulation of matrix metalloproteinase expression and invasiveness of glioma cells in a 3-dimensional collagen matrix
Q42475272Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity
Q41728604Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes
Q55463274Matrix metalloproteinase 2 attenuates brain tumour growth, while promoting macrophage recruitment and vascular repair.
Q41719486Matrix metalloproteinases and diseases of the CNS.
Q38151704Matrix metalloproteinases, new insights into the understanding of neurodegenerative disorders
Q36255730Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter
Q34444283Membrane-type matrix metalloproteinases (MT-MMPs): expression and function during glioma invasion
Q34297141Metalloproteinases in biology and pathology of the nervous system.
Q34108050Multi-agent cytostatic treatment of 'low-grade' gliomas
Q48561135Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix.
Q42525071PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells.
Q33760250Physiological roles of matrix metalloproteinases: implications for tumor growth and metastasis
Q34361140Process extension and myelin sheet formation in maturing oligodendrocytes
Q34627812Proteases and the biology of glioma invasion
Q47994379Protein kinase C isoforms in human aortic smooth muscle cells
Q36741102Regulation of C6 glioma cell migration by thymol.
Q40810854Regulation of MMP-9 (type IV collagenase) production and invasiveness in gliomas by the extracellular signal-regulated kinase and jun amino-terminal kinase signaling cascades
Q38411011Sp1 is upregulated in human glioma, promotes MMP-2-mediated cell invasion and predicts poor clinical outcome
Q37069961Stictamides A-C, MMP12 inhibitors containing 4-amino-3-hydroxy-5-phenylpentanoic acid subunits
Q34461935Substance P induces secretion of immunomodulatory cytokines by human astrocytoma cells
Q45881488Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.
Q40653941Targeting the cytotoxicity of fusogenic membrane glycoproteins in gliomas through protease–substrate interaction
Q37858940The brain tumor microenvironment.
Q37989468The brain tumor microenvironment.
Q33302115The chemokine receptor CXCR4 strongly promotes neuroblastoma primary tumour and metastatic growth, but not invasion
Q54652595The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase.
Q55475425The expression and activation of matrix metalloproteinase-2 in rat brain after implantation of C6 rat glioma cells.
Q37780433The perivascular niche microenvironment in brain tumor progression
Q36181275The potential use of MMP inhibitors to treat CNS diseases
Q36328452The role of matrix metalloproteinases in the morphogenesis of the cerebellar cortex
Q55476472The role of protein kinase Calpha in U-87 glioma invasion.
Q52573380The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.
Q44070484Ultrasensitive dual-channel detection of matrix metalloproteinase-2 in human serum using gold-quantum dot core-satellite nanoprobes
Q58698576miR-361-5p inhibits glioma migration and invasion by targeting SND1
Q38314591p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription.

Search more.