| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/0092-8674(95)90459-X |
| P698 | PubMed publication ID | 7813010 |
| P2093 | author name string | Ruppersberg JP | |
| Zenner HP | |||
| Fakler B | |||
| Brändle U | |||
| Glowatzki E | |||
| Weidemann S | |||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | voltage | Q25428 |
| P304 | page(s) | 149-154 | |
| P577 | publication date | 1995-01-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Strong voltage-dependent inward rectification of inward rectifier K+ channels is caused by intracellular spermine | |
| P478 | volume | 80 |
| Q36568525 | A K(+)-selective CNG channel orchestrates Ca(2+) signalling in zebrafish sperm. |
| Q52608794 | A Novel KCNJ2 Mutation Identified in an Autistic Proband Affects the Single Channel Properties of Kir2.1. |
| Q27636390 | A helical region in the C terminus of small-conductance Ca2+-activated K+ channels controls assembly with apo-calmodulin |
| Q24316252 | A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel |
| Q48939314 | A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation |
| Q41413007 | A novel dual-fluorescence strategy for functionally validating microRNA targets in 3' untranslated regions: regulation of the inward rectifier potassium channel K(ir)2.1 by miR-212. |
| Q48066130 | A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties |
| Q39446571 | A repolarization-induced transient increase in the outward current of the inward rectifier K+ channel in guinea-pig cardiac myocytes |
| Q46889643 | A unique P-region residue is required for slow voltage-dependent gating of a G protein-activated inward rectifier K+ channel expressed in Xenopus oocytes. |
| Q48063000 | A weakly inward rectifying potassium channel of the salmon brain. Glutamate 179 in the second transmembrane domain is insufficient for strong rectification |
| Q40370492 | ACAULIS5, an Arabidopsis gene required for stem elongation, encodes a spermine synthase. |
| Q33204326 | AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins |
| Q36248443 | Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons |
| Q58006155 | Amino Terminus and the First Four Membrane-spanning Segments of theArabidopsisK Channel KAT1 Confer Inward-rectification Property of Plant-Animal Chimeric Channels |
| Q40922838 | Amino acid substitutions in the pore of rat glutamate receptors at sites influencing block by polyamines |
| Q40929380 | Ammonia blockade of intestinal epithelial K+ conductance |
| Q48921102 | Architecture of a K+ channel inner pore revealed by stoichiometric covalent modification |
| Q34167570 | Assembly of ROMK1 (Kir 1.1a) inward rectifier K+ channel subunits involves multiple interaction sites |
| Q28294804 | Binding of the inward rectifier K+ channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylation |
| Q42642248 | Block of large conductance Ca(2+)-activated K+ channels in rabbit vascular myocytes by internal Mg2+ and Na+. |
| Q71513383 | Block of native Ca(2+)-permeable AMPA receptors in rat brain by intracellular polyamines generates double rectification |
| Q36436070 | Block of the Kir2.1 channel pore by alkylamine analogues of endogenous polyamines |
| Q36420571 | Blockade of a retinal cGMP-gated channel by polyamines |
| Q36908420 | Blocker protection by short spermine analogs: refined mapping of the spermine binding site in a Kir channel |
| Q38819091 | Boosting the signal: Endothelial inward rectifier K+ channels |
| Q37624790 | C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1. |
| Q41103315 | Calcium permeability of glutamate-gated channels in the central nervous system |
| Q48756736 | Carbon dioxide regulates the tonic activity of locus coeruleus neurons by modulating a proton- and polyamine-sensitive inward rectifier potassium current |
| Q48293093 | Cardiac Potassium Channels: Physiological Insights for Targeted Therapy. |
| Q38201409 | Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia |
| Q47772758 | Cardiac potassium channels in health and disease |
| Q41639367 | Cardiac potassium currents and channels--part I: basic science aspects |
| Q37585689 | Cardiac strong inward rectifier potassium channels |
| Q38118863 | Cell proliferation, potassium channels, polyamines and their interactions: a mini review |
| Q35201276 | Cell signal control of the G protein-gated potassium channel and its subcellular localization |
| Q35184527 | Cerebellar granule cells as a model to study mechanisms of neuronal apoptosis or survival in vivo and in vitro |
| Q36493629 | Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels |
| Q49031633 | Cloned Human Inward Rectifier K + Channel as a Target for Class III Methanesulfonanilides |
| Q24312802 | Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3) |
| Q57374697 | Cloning and expression of cardiac Kir2.1 and Kir2.2 channels in thermally acclimated rainbow trout |
| Q34075247 | Cloning and expression of two brain-specific inwardly rectifying potassium channels |
| Q24322962 | Cloning of a G protein-activated inwardly rectifying potassium channel from human cerebellum |
| Q28361734 | Comparison of cloned Kir2 channels with native inward rectifier K+ channels from guinea-pig cardiomyocytes |
| Q39323368 | Complex rectification of Müller cell Kir currents. |
| Q40238701 | Contribution of cytosolic cysteine residues to the gating properties of the Kir2.1 inward rectifier |
| Q34017156 | Contributions of a negatively charged residue in the hydrophobic domain of the IRK1 inwardly rectifying K+ channel to K(+)-selective permeation |
| Q28360309 | Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel |
| Q36852275 | Coupled ion movement underlies rectification in an inward-rectifier K+ channel |
| Q27646617 | Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 A Resolution |
| Q36439784 | Cytoplasmic amino and carboxyl domains form a wide intracellular vestibule in an inwardly rectifying potassium channel |
| Q46715166 | Dendritic excitability of mouse frontal cortex pyramidal neurons is shaped by the interaction among HCN, Kir2, and Kleak channels. |
| Q37279735 | Depletion of intracellular polyamines relieves inward rectification of potassium channels |
| Q43916450 | Differential distribution of spermidine/spermine-like immunoreactivity in neurons of the adult rat brain |
| Q46864582 | Differential polyamine sensitivity in inwardly rectifying Kir2 potassium channels |
| Q37532733 | Differential subunit composition of the G protein-activated inward-rectifier potassium channel during cardiac development |
| Q58063090 | Divalent cation gating of an ammonium permeable channel in the symbiotic membrane from soybean nodules |
| Q39180540 | Downregulation of Spermine Augments Dendritic Persistent Sodium Currents and Synaptic Integration after Status Epilepticus. |
| Q42527227 | Effects of secretagogues on insulin biosynthesis and secretion in polyamine-depleted pancreatic beta-cells |
| Q39628706 | Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels. |
| Q36999883 | Endogenous polyamines regulate cortical neuronal excitability by blocking voltage-gated Na+ channels |
| Q41980695 | Evidence for sequential ion-binding loci along the inner pore of the IRK1 inward-rectifier K+ channel |
| Q37377763 | Evidence for the direct interaction of spermine with the inwardly rectifying potassium channel |
| Q40224510 | External action of di- and polyamines on maxi calcium-activated potassium channels: an electrophysiological and molecular modeling study |
| Q50761103 | Extracellular K+ and intracellular pH allosterically regulate renal Kir1.1 channels. |
| Q36411776 | Fast inactivation causes rectification of the IKr channel |
| Q42556484 | Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells |
| Q36295651 | Functional roles of charged amino acid residues on the wall of the cytoplasmic pore of Kir2.1. |
| Q48890729 | GABAB receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons |
| Q37775217 | GABAB-GIRK2-mediated signaling in Down syndrome. |
| Q42508087 | Galphai3 primes the G protein-activated K+ channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes. |
| Q74005798 | Gating of Ca2+-activated K+ channels controls fast inhibitory synaptic transmission at auditory outer hair cells |
| Q40713333 | Giant excised patch recordings of recombinant ion channel currents expressed in mammalian cells |
| Q40077162 | Heterogeneity of IK1 in the mouse heart |
| Q30478958 | High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1. |
| Q27867696 | Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study |
| Q38703390 | Hydrocinnamic Acid Inhibits the Currents of WT and SQT3 Syndrome-Related Mutants of Kir2.1 Channel. |
| Q36436459 | IRK1 inward rectifier K(+) channels exhibit no intrinsic rectification |
| Q35906127 | Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH. |
| Q48891653 | Impermeability of the GIRK2 weaver channel to divalent cations |
| Q40178283 | Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms |
| Q28584777 | Increased excitability and inward rectification in layer V cortical pyramidal neurons in the epileptic mutant mouse Stargazer |
| Q36331012 | Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP2 interference |
| Q36436623 | Interaction Mechanisms between Polyamines and IRK1 Inward Rectifier K+ Channels |
| Q34167792 | Interaction of permeant and blocking ions in cloned inward-rectifier K+ channels |
| Q36353465 | Interactions of external K+ and internal blockers in a weak inward-rectifier K+ channel |
| Q41537541 | Interactions of polyamines with ion channels |
| Q52196171 | Interference with DNA methyltransferase activity and genome methylation during F9 teratocarcinoma stem cell differentiation induced by polyamine depletion. |
| Q33898418 | Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors |
| Q38419973 | Intracellular spermine blocks TRPC4 channel via electrostatic interaction with C-terminal negative amino acids |
| Q57985787 | Intracellular spermine confers rectification on rat calcium-permeable AMPA and kainate receptors |
| Q44436440 | Inward Rectification by Polyamines in Mouse Kir2.1 Channels: Synergy between Blocking Components |
| Q33852328 | Inward rectification in KATP channels: a pH switch in the pore. |
| Q41316722 | Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block |
| Q34017910 | Inward rectification of the IRK1 K+ channel reconstituted in lipid bilayers |
| Q43977795 | Inward rectifier K(+) current under physiological cytoplasmic conditions in guinea-pig cardiac ventricular cells |
| Q26865121 | Inward rectifiers and their regulation by endogenous polyamines |
| Q37013945 | Inward-rectifying potassium (Kir) channels regulate pacemaker activity in spinal nociceptive circuits during early life |
| Q46722116 | Inwardly rectifying K+ channels in freshly dissociated coronary endothelial cells from guinea-pig heart |
| Q24296441 | Inwardly rectifying potassium channels: their structure, function, and physiological roles |
| Q40953646 | Ion channels. A physiological function for polyamines? |
| Q34099241 | Ion conduction pore is conserved among potassium channels |
| Q28343339 | K(+)-dependent gating of K(ir)1.1 channels is linked to pH gating through a conformational change in the pore |
| Q28185346 | KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel |
| Q36444667 | Kinetics of inward-rectifier K+ channel block by quaternary alkylammonium ions. dimension and properties of the inner pore |
| Q24317591 | Kir2.4: a novel K+ inward rectifier channel associated with motoneurons of cranial nerve nuclei |
| Q33814279 | Locale and chemistry of spermine binding in the archetypal inward rectifier Kir2.1. |
| Q42603548 | Localization of PIP2 activation gate in inward rectifier K+ channels |
| Q40404510 | Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels |
| Q36493585 | Long polyamines act as cofactors in PIP2 activation of inward rectifier potassium (Kir2.1) channels |
| Q44619532 | Long-chain acyl-CoA esters and phosphatidylinositol phosphates modulate ATP inhibition of KATP channels by the same mechanism |
| Q40104801 | Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels |
| Q41701582 | Magnesium Sensitizes Slow Vacuolar Channels to Physiological Cytosolic Calcium and Inhibits Fast Vacuolar Channels in Fava Bean Guard Cell Vacuoles |
| Q46020057 | Magnesium-independent activation of inward-rectifying K+ channels in Vicia faba guard cells. |
| Q41089138 | Mapping the kidney potassium channel ROMK1. Glycosylation of the pore signature sequence and the COOH terminus |
| Q28344014 | Mechanism of Ba(2+) block of a mouse inwardly rectifying K+ channel: differential contribution by two discrete residues |
| Q36442925 | Mechanism of IRK1 channel block by intracellular polyamines |
| Q36442929 | Mechanism of cGMP-gated channel block by intracellular polyamines |
| Q42978407 | Mechanism of rectification in inward-rectifier K+ channels |
| Q36412643 | Mechanism of the voltage sensitivity of IRK1 inward-rectifier K+ channel block by the polyamine spermine |
| Q36412396 | Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6. |
| Q35953724 | Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes |
| Q28367641 | Modification of voltage-dependent gating of potassium channels by free form of tryptophan side chain |
| Q41380609 | Modulation and block of ion channels: a new biology of polyamines |
| Q35044896 | Monovalent cation (MC) current in cardiac and smooth muscle cells: regulation by intracellular Mg2+ and inhibition by polycations |
| Q37398408 | Multiple residues in the p-region and m2 of murine kir 2.1 regulate blockage by external ba. |
| Q39627863 | NMR analysis of KChIP4a reveals structural basis for control of surface expression of Kv4 channel complexes. |
| Q27634290 | NMR structure of the "ball-and-chain" domain of KCNMB2, the beta 2-subunit of large conductance Ca2+- and voltage-activated potassium channels |
| Q48939796 | Neuronal nicotinic acetylcholine receptors are blocked by intracellular spermine in a voltage-dependent manner. |
| Q41026173 | Neutralization of aspartate residues in the murine inwardly rectifying K+ channel IRK1 affects the substate behaviour in Mg2+ block |
| Q41694238 | New views of multi-ion channels. |
| Q36412119 | Novel gating mechanism of polyamine block in the strong inward rectifier K channel Kir2.1. |
| Q42063702 | Novel sites of N-glycosylation in ROMK1 reveal the putative pore-forming segment H5 as extracellular |
| Q36690601 | ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae |
| Q39453945 | Permeation and block of rat GluR6 glutamate receptor channels by internal and external polyamines |
| Q41060367 | Pharmacological implications of inward rectifier K+ channels regulation by cytoplasmic polyamines |
| Q44270128 | Phosphatidylinositol 4,5-bisphosphate (PIP2) modulation of ATP and pH sensitivity in Kir channels. A tale of an active and a silent PIP2 site in the N terminus |
| Q27658191 | Physical determinants of strong voltage sensitivity of K+ channel block |
| Q48933599 | Polyamine spider toxins and mammalian N-methyl-D-aspartate receptors. Structural basis for channel blocking and binding of argiotoxin636. |
| Q44297173 | Polyamine transport, accumulation, and release in brain. |
| Q58544829 | Polyamines and potassium channels: A twenty five year romance |
| Q34039970 | Polyamines as gating molecules of inward-rectifier K+ channels |
| Q36323217 | Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system. |
| Q34180818 | Polyvalent cations as permeant probes of MIC and TRPM7 pores |
| Q36438882 | Pore block versus intrinsic gating in the mechanism of inward rectification in strongly rectifying IRK1 channels |
| Q30538302 | Positive feedback by a potassium-selective inward rectifier enhances tuning in vertebrate hair cells |
| Q41333845 | Potassium channel structure and function as reported by a single glycosylation sequon |
| Q34127747 | Potassium transport in the mammalian collecting duct |
| Q48946365 | Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants |
| Q27026601 | Redefining the classification of AMPA-selective ionotropic glutamate receptors |
| Q44040479 | Regulation of IRK3 Inward RectifierK + Channel by m1 Acetylcholine Receptorand Intracellular Magnesium |
| Q48811487 | Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel |
| Q44196779 | Regulation of the inward rectifying properties of G-protein-activated inwardly rectifying K+ (GIRK) channels by Gbeta gamma subunits |
| Q48741212 | Repolarizing responses of BKCa-Cav complexes are distinctly shaped by their Cav subunits. |
| Q50724379 | Residues and mechanisms for slow activation and Ba2+ block of the cardiac muscarinic K+ channel, Kir3.1/Kir3.4. |
| Q34539565 | Scanning the topography of polyamine blocker binding in an inwardly rectifying potassium channel. |
| Q42988892 | Selective labelling of cell-surface polyamine-binding proteins on leukaemic and solid-tumour cell types using a new polyamine photoprobe |
| Q36009629 | Sensitivity of cloned muscle, heart and neuronal voltage-gated sodium channels to block by polyamines: a possible basis for modulation of excitability in vivo |
| Q36436571 | Ser165 in the second transmembrane region of the Kir2.1 channel determines its susceptibility to blockade by intracellular Mg2+. |
| Q40734306 | Site-directed glycosylation tagging of functional Kir2.1 reveals that the putative pore-forming segment is extracellular |
| Q33603023 | Small-molecule modulators of inward rectifier K+ channels: recent advances and future possibilities |
| Q39195631 | Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles |
| Q30101028 | Somatostatin Depresses the Excitability of Subicular Bursting Cells: Roles of Inward Rectifier K+ Channels, KCNQ channels and Epac |
| Q73804989 | Spatial distribution of spermine/spermidine content and K(+)-current rectification in frog retinal glial (Müller) cells |
| Q33430194 | Specific and slow inhibition of the kir2.1 K+ channel by gambogic acid |
| Q49019498 | Spermidine release from xenopus oocytes. Electrodiffusion through a membrane channel |
| Q46974195 | Spermidine synthase is prominently expressed in the striatal patch compartment and in putative interneurones of the matrix compartment |
| Q77594776 | Spermine affects intestinal in vitro permeability to different-sized molecules in rats |
| Q36558213 | Spermine block of the strong inward rectifier potassium channel Kir2.1: dual roles of surface charge screening and pore block |
| Q48580612 | Spermine does not compete with omega-conotoxin GVIA in the striatum radiatum of the hippocampal slice |
| Q43565332 | Spermine mediates inward rectification in potassium channels of turtle retinal Müller cells |
| Q42160318 | Spermine suppresses the activation of human neutrophil NADPH oxidase in cell-free and semi-recombinant systems |
| Q40188995 | Structural Basis for Asymmetric Conductance of the Influenza M2 Proton Channel Investigated by Solid-State NMR Spectroscopy. |
| Q92353914 | Structure-Function Relationship and Physiological Roles of Transient Receptor Potential Canonical (TRPC) 4 and 5 Channels |
| Q39474348 | Styrax blocks inward and outward current of Kir2.1 channel |
| Q38289088 | Subunit-specific inhibition of inward-rectifier K+ channels by quinidine |
| Q33368209 | The ABCs of ATP-sensitive potassium channels: more pieces of the puzzle |
| Q52312305 | The Ba2+ block of the ATP-sensitive K+ current of mouse pancreatic beta-cells. |
| Q33944447 | The S4-S5 linker couples voltage sensing and activation of pacemaker channels. |
| Q42610159 | The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel. |
| Q34515808 | The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes |
| Q34476854 | The epithelial inward rectifier channel Kir7.1 displays unusual K+ permeation properties. |
| Q36295661 | The polyamine binding site in inward rectifier K+ channels. |
| Q38278661 | The role of glia in stress: polyamines and brain disorders |
| Q36296035 | The role of the cytoplasmic pore in inward rectification of Kir2.1 channels |
| Q28379235 | The tetravalent organic cation spermine causes the gating of the IRK1 channel expressed in murine fibroblast cells |
| Q50761569 | Time, voltage and ionic concentration dependence of rectification of h-erg expressed in Xenopus oocytes. |
| Q39458210 | Time-dependent outward currents through the inward rectifier potassium channel IRK1. The role of weak blocking molecules. |
| Q46880917 | Transient outward current carried by inwardly rectifying K+ channels in guinea pig ventricular myocytes dialyzed with low-K+ solution |
| Q36436227 | Tuning the voltage dependence of tetraethylammonium block with permeant ions in an inward-rectifier K+ channel |
| Q41055990 | Two mechanisms for inward rectification of current flow through the purinoceptor P2X2 class of ATP-gated channels |
| Q39385587 | Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by a study of the Kir2.1 channel expressed in a human cell line |
| Q44121146 | Two types of nicotinic receptors mediate an excitation of neocortical layer I interneurons. |
| Q90412287 | Upregulation of Potassium Voltage-Gated Channel Subfamily J Member 2 Levels in the Lungs of Patients with Idiopathic Pulmonary Fibrosis |
| Q36436195 | Voltage-dependent gating of single wild-type and S4 mutant KAT1 inward rectifier potassium channels |
| Q41677912 | Voltage-gated and inwardly rectifying potassium channels |
| Q34040281 | [K+] dependence of open-channel conductance in cloned inward rectifier potassium channels (IRK1, Kir2.1) |
| Q36787083 | pH gating of ROMK (K(ir)1.1) channels: control by an Arg-Lys-Arg triad disrupted in antenatal Bartter syndrome |
| Q38330465 | pH-dependent gating of ROMK (Kir1.1) channels involves conformational changes in both N and C termini |
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