Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains

scientific article published on 25 January 2018

Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains is …
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scholarly articleQ13442814

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P356DOI10.2147/IDR.S152082
P932PMC publication ID5790067
P698PubMed publication ID29416362

P50authorRavindra P TurankarQ60981261
P2093author name stringUtpal Sengupta
Anuj Kumar Gupta
Mallika Lavania
Itu Singh
Madhvi Ahuja
Vinay Pathak
P2860cites workSurvey for secondary dapsone and rifampicin resistance in Cuba.Q39027806
Drug resistance patterns in Mycobacterium leprae isolates from relapsed leprosy patients attending The Leprosy Mission (TLM) Hospitals in IndiaQ41687700
Drug resistance in Mycobacterium leprae from patients with leprosy in ChinaQ41727663
Monooxygenation of rifampicin catalyzed by the rox gene product of Nocardia farcinica: structure elucidation, gene identification and role in drug resistanceQ43234798
Mutation at codon 442 in the rpoB gene of Mycobacterium leprae does not confer resistance to rifampicin.Q51723991
A Mycobacterium leprae isolate resistant to dapsone, rifampin, ofloxacin and sparfloxacin.Q54011152
Emergence of primary drug resistance to rifampicin in Mycobacterium leprae strains from leprosy patients in India.Q54250021
Comparative genomic and phylogeographic analysis of Mycobacterium lepraeQ57219307
Multidrug-resistance to dapsone, rifampicin, and ofloxacin in Mycobacterium lepraeQ71976010
Single nucleotide polymorphisms typing of Mycobacterium leprae reveals focal transmission of leprosy in high endemic regions of IndiaQ85919473
Massive gene decay in the leprosy bacillusQ22122381
Detection of rifampicin-resistance mutations in Mycobacterium tuberculosisQ28248794
mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatisQ28487615
Co-infection of Mycobacterium tuberculosis and Mycobacterium leprae in human archaeological samples: a possible explanation for the historical decline of leprosyQ28766858
Multidrug resistant Mycobacterium leprae from patients with leprosy.Q31030417
The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins.Q33913686
Contribution of rpoB2 RNA polymerase beta subunit gene to rifampin resistance in Nocardia speciesQ34510650
Identification of primary drug resistance to rifampin in Mycobacterium leprae strains from leprosy patients in Amazonas State, BrazilQ35036286
Molecular basis of rifampin resistance in Mycobacterium lepraeQ35809886
Distribution of Mycobacterium leprae strains among cases in a rural and urban population of Maharashtra, IndiaQ35867753
Drug and multidrug resistance among Mycobacterium leprae isolates from Brazilian relapsed leprosy patientsQ36023028
Influence of initial drug resistance on the response to short-course chemotherapy of pulmonary tuberculosis.Q38160741
Leprosy and tuberculosis concomitant infection: a poorly understood, age-old relationshipQ38353059
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectMycobacterium lepraeQ155891
whole genome sequencingQ2068526
P304page(s)169-175
P577publication date2018-01-25
P1433published inInfection and Drug ResistanceQ15716352
P1476titleEnriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains
P478volume11

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