| P50 | author | Luke I Szweda | Q63072371 |
| | Holly Van Remmen | Q78838825 |
| P2093 | author name string | Willard M Freeman | |
| | Michael Kinter | |
| | Benjamin Wronowski | |
| | Dustin R Masser | |
| | William E Sonntag | |
| | Julie A Farley | |
| | Kenneth M Humphries | |
| | Satoshi Matsuzaki | |
| | Sreemathi Logan | |
| | Pavithra Premkumar | |
| | Alexander Yeganeh | |
| | Daniel B Owen | |
| | Eileen E Parks | |
| | M Caleb Marlin | |
| | Gavin A Pharaoh | |
| P2860 | cites work | Impaired brain development and reduced astrocyte response to injury in transgenic mice expressing IGF binding protein-1. | Q48592071 |
| | The insulin-like growth factor I receptor regulates glucose transport by astrocytes. | Q48601088 |
| | Short stature and cardiovascular disease among men and women from two southeastern New England communities. | Q52223908 |
| | Amyloid beta-protein (Abeta)-containing astrocytes are located preferentially near N-terminal-truncated Abeta deposits in the human entorhinal cortex. | Q53343797 |
| | IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan. | Q54405530 |
| | Respiratory enzymes in oxidative phosphorylation. III. The steady state. | Q55037006 |
| | Bioenergetic role of mitochondrial fusion and fission | Q63359585 |
| | Insulin-like growth factor 1 stimulates protein synthesis and inhibits protein breakdown in muscle from burned rats | Q73765101 |
| | Synapses and Alzheimer's disease | Q26269868 |
| | Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? | Q26853196 |
| | Mitochondrial form and function | Q26866448 |
| | Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease | Q27302961 |
| | Purinergic receptor stimulation reduces cytotoxic edema and brain infarcts in mouse induced by photothrombosis by energizing glial mitochondria | Q27315062 |
| | IGF-1, oxidative stress and atheroprotection | Q27694593 |
| | The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 |
| | Insulin-like growth factor-1 deficiency and metabolic syndrome | Q28072410 |
| | Minireview: The Complexities of IGF/Insulin Signaling in Aging: Why Flies and Worms Are Not Humans | Q28085566 |
| | Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling | Q28574687 |
| | SLP-2 is required for stress-induced mitochondrial hyperfusion | Q28594182 |
| | AMPK: a nutrient and energy sensor that maintains energy homeostasis | Q29615410 |
| | During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. | Q29616569 |
| | A central role for JNK in obesity and insulin resistance | Q29619778 |
| | Neutral red uptake assay for the estimation of cell viability/cytotoxicity | Q30047632 |
| | Growth hormone and IGF-I modulate local cerebral glucose utilization and ATP levels in a model of adult-onset growth hormone deficiency. | Q48446291 |
| | Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection. | Q48475739 |
| | Brain and cerebrovascular aging--new mechanisms and insights. | Q48490848 |
| | Working memory training promotes general cognitive abilities in genetically heterogeneous mice | Q30495688 |
| | Long-lived ames dwarf mice are resistant to chemical stressors | Q30497373 |
| | Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion | Q30542646 |
| | Insulin-like growth factor-1 selectively increases glucose utilization in brains of aged animals. | Q31806595 |
| | Early-onset GH deficiency results in spatial memory impairment in mid-life and is prevented by GH supplementation | Q33652067 |
| | The sites and topology of mitochondrial superoxide production | Q33888976 |
| | The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes | Q33892083 |
| | Oxidative stress, mitochondrial damage and neurodegenerative diseases | Q34094532 |
| | Lactate produced by glycogenolysis in astrocytes regulates memory processing | Q34105200 |
| | The effects of growth hormone and IGF-1 deficiency on cerebrovascular and brain ageing | Q34150795 |
| | Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice | Q34229672 |
| | Astrocyte-Specific Overexpression of Insulin-Like Growth Factor-1 Protects Hippocampal Neurons and Reduces Behavioral Deficits following Traumatic Brain Injury in Mice | Q34796693 |
| | Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression | Q35004325 |
| | Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation | Q35064216 |
| | Reductions in serum IGF-1 during aging impair health span. | Q35080501 |
| | The role of astrocyte mitochondria in differential regional susceptibility to environmental neurotoxicants: tools for understanding neurodegeneration | Q35145894 |
| | Mitochondrial respiration and redox coupling in articular chondrocytes | Q35257654 |
| | Growth hormone, insulin-like growth factor-1 and the aging brain. | Q35305216 |
| | Insulin and Insulin-like Growth Factor 1 (IGF-1) Modulate Cytoplasmic Glucose and Glycogen Levels but Not Glucose Transport across the Membrane in Astrocytes | Q35536348 |
| | Expression of oxidative phosphorylation components in mitochondria of long-living Ames dwarf mice | Q35678101 |
| | Free radicals: key to brain aging and heme oxygenase as a cellular response to oxidative stress | Q35763186 |
| | Free radicals and brain aging | Q35795706 |
| | Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline | Q35858095 |
| | Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability | Q35868150 |
| | Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1 | Q35947448 |
| | Glycogen and amyloid-beta: key players in the shift from neuronal hyperactivity to hypoactivity observed in Alzheimer's disease? | Q35969643 |
| | Association between Cognition and Serum Insulin-Like Growth Factor-1 in Middle-Aged & Older Men: An 8 Year Follow-Up Study | Q35999384 |
| | Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging | Q36197707 |
| | Mitochondrial oxidant generation and oxidative damage in Ames dwarf and GH transgenic mice | Q36270598 |
| | The NF-kappaB-mediated control of ROS and JNK signaling. | Q36305535 |
| | IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging | Q36410004 |
| | Hydrogen peroxide: a signaling messenger | Q36469258 |
| | Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline | Q36475254 |
| | Mitoenergetic failure in Alzheimer disease | Q36522646 |
| | Human Cortical Neural Stem Cells Expressing Insulin-Like Growth Factor-I: A Novel Cellular Therapy for Alzheimer's Disease | Q36728537 |
| | Calorie restriction: is AMPK a key sensor and effector? | Q36767838 |
| | Modeling the neuroprotective role of enhanced astrocyte mitochondrial metabolism during stroke | Q36770471 |
| | Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice | Q36865241 |
| | Ablation of the mitochondrial complex IV assembly protein Surf1 leads to increased expression of the UPR(MT) and increased resistance to oxidative stress in primary cultures of fibroblasts | Q36930913 |
| | Insulin-like growth factor-1 in CNS and cerebrovascular aging | Q36973428 |
| | Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice | Q37038972 |
| | Oxidative damage associated with obesity is prevented by overexpression of CuZn- or Mn-superoxide dismutase | Q37158580 |
| | Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E. | Q37497056 |
| | ABC transporters in the CNS - an inventory | Q37813717 |
| | Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation | Q37966074 |
| | Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury | Q38273037 |
| | Astrocyte Resilience to Oxidative Stress Induced by Insulin-like Growth Factor I (IGF-I) Involves Preserved AKT (Protein Kinase B) Activity. | Q39284593 |
| | Multifunctional role of astrocytes as gatekeepers of neuronal energy supply | Q39734463 |
| | IGF-1 stimulates protein synthesis by enhanced signaling through mTORC1 in bovine mammary epithelial cells | Q39738168 |
| | Low Serum Insulin-Like Growth Factor-I Predicts Cognitive Decline in Alzheimer's Disease. | Q39875278 |
| | Mitochondrial elongation during autophagy: a stereotypical response to survive in difficult times. | Q39912206 |
| | Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance. | Q40625519 |
| | Activation of NF-kappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells | Q41279171 |
| | Quantifying intracellular hydrogen peroxide perturbations in terms of concentration | Q41742488 |
| | In vivo and in vitro assessment of brain bioenergetics in aging rats | Q41807410 |
| | Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice | Q41839448 |
| | Long-living Ames dwarf mouse hepatocytes readily undergo apoptosis | Q42447056 |
| | A network of insulin peptides regulate glucose uptake by astrocytes: Potential new druggable targets for brain hypometabolism | Q42514263 |
| | Astrocytic metabolic and inflammatory changes as a function of age. | Q43034853 |
| | Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study | Q43427739 |
| | Transient upregulation of the glial glutamate transporter GLAST in response to fibroblast growth factor, insulin-like growth factor and epidermal growth factor in cultured astrocytes. | Q43798622 |
| | Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis | Q43807507 |
| | Impaired cardiac excitation-contraction coupling in ventricular myocytes from Ames dwarf mice with IGF-I deficiency | Q44100211 |
| | Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice | Q44183231 |
| | Changes in brain glycogen after sleep deprivation vary with genotype. | Q44429128 |
| | Genetic variation at the IGF1 locus shows association with post-stroke outcome and to circulating IGF1. | Q44797658 |
| | Long-lived Ames dwarf mouse exhibits increased antioxidant defense in skeletal muscle | Q44828837 |
| | A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease | Q45291617 |
| | Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease. | Q45987250 |
| | Astrocytes and interneurons in memory processing in the chick hippocampus: roles for G-coupled protein receptors, GABA(B) and mGluR1. | Q46025530 |
| | Rescue of Abeta(1-42)-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: implications for Alzheimer's disease. | Q46037689 |
| | Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons | Q46625125 |
| | Growth hormone administration to aged animals reduces disulfide glutathione levels in hippocampus | Q46769086 |
| | Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse. | Q46832187 |
| | Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers. | Q47120381 |
| | CrossTalk proposal: an important astrocyte-to-neuron lactate shuttle couples neuronal activity to glucose utilisation in the brain. | Q47887492 |
| | Simultaneous age-related depolarization of mitochondrial membrane potential and increased mitochondrial reactive oxygen species production correlate with age-related glutamate excitotoxicity in rat hippocampal neurons | Q48254848 |
| | Insulin-like growth factor-1 ameliorates age-related behavioral deficits. | Q48383001 |
| | Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I. | Q48388330 |
| P921 | main subject | astrocyte | Q502961 |
| P304 | page(s) | 141-155 | |
| P577 | publication date | 2018-02-02 | |
| P1433 | published in | Molecular Metabolism | Q27724805 |
| P1476 | title | Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes | |
| P478 | volume | 9 | |