MiR-124 acts as a target for Alzheimer's disease by regulating BACE1.

scientific article published on 9 December 2017

MiR-124 acts as a target for Alzheimer's disease by regulating BACE1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.23119
P932PMC publication ID5768386
P698PubMed publication ID29371969

P2093author name stringYu Wang
Lijun Yu
Chengxi Wei
Guohua Gong
Ming Bian
Fengmao An
P2860cites workPathways towards and away from Alzheimer's diseaseQ24596270
MicroRNAs: target recognition and regulatory functionsQ24609584
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?Q27860893
Asynchronous evolutionary origins of Aβ and BACE1Q28658612
microRNAs: important regulators of stem cellsQ33660277
The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.Q33722837
MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neuronsQ33897760
The emerging role of microRNAs in Alzheimer's diseaseQ35076344
MicroRNA-124 is a subventricular zone neuronal fate determinant.Q35614391
An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesisQ35654340
NF-κB-mediated miR-124 suppresses metastasis of non-small-cell lung cancer by targeting MYO10.Q35781552
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expressionQ36609033
MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neuronsQ37261417
miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signallingQ39347979
Cadmium and Alzheimer's disease mortality in U.S. adults: Updated evidence with a urinary biomarker and extended follow-up timeQ40199289
MiR-124 acts as a tumor suppressor by inhibiting the expression of sphingosine kinase 1 and its downstream signaling in head and neck squamous cell carcinomaQ42120428
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsivenessQ45736205
The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease.Q48770351
Alzheimer disease: BACE1 inhibitor reduces β-amyloid production in humans.Q51229646
MicroRNA-124 suppresses tumor cell proliferation and invasion by targeting CD164 signaling pathway in non-small cell lung cancerQ87815883
P433issue69
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
Beta-secretase 1Q737488
positive regulation of neuron apoptotic processQ14818065
P304page(s)114065-114071
P577publication date2017-12-09
P1433published inOncotargetQ1573155
P1476titleMiR-124 acts as a target for Alzheimer's disease by regulating BACE1.
P478volume8

Reverse relations

cites work (P2860)
Q64068117Amyloid Beta and MicroRNAs in Alzheimer’s Disease
Q91637583MicroRNAs in Alzheimer's Disease: Diagnostic Markers or Therapeutic Agents?
Q64998505Non-coding RNA influences in dementia.
Q91741329Roles of Non-Coding RNAs in Normal Human Brain Development, Brain Tumor, and Neuropsychiatric Disorders
Q90461848The MicroRNA Centrism in the Orchestration of Neuroinflammation in Neurodegenerative Diseases
Q92257585The Potential Role of MicroRNA-124 in Cerebral Ischemia Injury
Q64962410miR-194 Accelerates Apoptosis of Aβ1⁻42-Transduced Hippocampal Neurons by Inhibiting Nrn1 and Decreasing PI3K/Akt Signaling Pathway Activity.

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