Matrix metalloproteinase-1 facilitates MSC migration via cleavage of IGF-2/IGFBP2 complex

scientific article published on 23 November 2017

Matrix metalloproteinase-1 facilitates MSC migration via cleavage of IGF-2/IGFBP2 complex is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/2211-5463.12330
P932PMC publication ID5757182
P698PubMed publication ID29321953

P2093author name stringJennifer P Newman
Paula Y P Lam
Melvin L K Chua
Kevin L M Chua
Catherine Y L Kok
Alan T L Lam
Shou P Guan
Siao T Chong
P2860cites workSignaling molecules and pathways involved in MSC tumor tropismQ38119884
Determination of IGFs and their binding proteins.Q38166098
Mesenchymal stem cell carriers enhance antitumor efficacy of oncolytic adenoviruses in an immunocompetent mouse model.Q38702903
EGFR and IGF-1R in regulation of prostate cancer cell phenotype and polarity: opposing functions and modulation by T-cadherin.Q38941748
Id4 suppresses MMP2-mediated invasion of glioblastoma-derived cells by direct inactivation of Twist1 function.Q39035362
Insulin-like growth factor-binding protein-2 promotes prostate cancer cell growth via IGF-dependent or -independent mechanisms and reduces the efficacy of docetaxelQ39559581
Human mesenchymal stem cells overexpressing pigment epithelium-derived factor inhibit hepatocellular carcinoma in nude miceQ39733970
Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer.Q39852557
Endothelial progenitor cell homing: prominent role of the IGF2-IGF2R-PLCbeta2 axisQ39932996
Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomasQ39970885
HSV-1 amplicon viral vector-mediated gene transfer to human bone marrow-derived mesenchymal stem cells.Q39974606
Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.Q40159420
MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines.Q40188347
PAR-type thrombin receptors in renal carcinoma cells: PAR1-mediated EGFR activation promotes cell migrationQ40307139
Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cellsQ40371413
Activation of proteinase-activated receptor 1 promotes human colon cancer cell proliferation through epidermal growth factor receptor transactivation.Q40512566
Insulin-like growth factor (IGF)-independent effects of IGF binding protein-4 on human granulosa cell steroidogenesisQ44112745
The role of G-protein signaling in hematopoietic stem/progenitor cell mobilization.Q52549424
IGF-I and IGF-II stimulate directed cell migration of bone-marrow-derived human mesenchymal progenitor cells.Q53621706
Insulin-like growth factor 1 enhances the migratory capacity of mesenchymal stem cellsQ80027788
The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activitiesQ80065296
Stem Cell-Based Cell Carrier for Targeted Oncolytic Virotherapy: Translational Opportunity and Open QuestionsQ26775038
Patient-derived mesenchymal stem cells as delivery vehicles for oncolytic virotherapy: novel state-of-the-art technologyQ26821929
Engineering mesenchymal stem cells for regenerative medicine and drug deliveryQ27026414
Cellular actions of the insulin-like growth factor binding proteinsQ28216659
The role of the M6P/IGF-II receptor in cancer: tumor suppression or garbage disposal?Q28262838
Insulin-like growth factors and their binding proteins: biological actionsQ28301853
The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endotheliumQ28508627
A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: activation of proteinase-activated receptor 1 and epidermal growth factor receptorQ33615794
The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasionQ33665441
Role of insulin receptors and IGF receptors in growth and developmentQ33982157
Epigenetic Upregulation of Urokinase Plasminogen Activator Promotes the Tropism of Mesenchymal Stem Cells for Tumor CellsQ34073304
Matrix metalloproteinases in tumor invasion and metastasisQ34136635
The insulin-like growth factor system and cancerQ34200058
IGF2 actions on trophoblast in human placenta are regulated by the insulin-like growth factor 2 receptor, which can function as both a signaling and clearance receptorQ34594074
Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells.Q34884392
Directing systemic oncolytic viral delivery to tumors via carrier cellsQ35029126
NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expressionQ35051738
Insulin-like growth factor binding protein proteolysisQ35114599
IGF binding protein 2 supports the survival and cycling of hematopoietic stem cellsQ35230193
Effects of insulin-like growth factor-1 on the properties of mesenchymal stem cells in vitroQ35653335
Oncogenic activation in prostate cancer progression and metastasis: Molecular insights and future challengesQ35838821
Regenerative effects of transplanted mesenchymal stem cells in fracture healingQ36185562
Matrix metalloproteinases and cellular motility in development and disease.Q36452765
Mesenchymal stem cells expressing insulin-like growth factor-I (MSCIGF) promote fracture healing and restore new bone formation in Irs1 knockout mice: analyses of MSCIGF autocrine and paracrine regenerative effects.Q36755738
Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cellsQ37134013
Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cellsQ37285238
PRL1 promotes cell migration and invasion by increasing MMP2 and MMP9 expression through Src and ERK1/2 pathwaysQ37395771
Interactions of IGF-II with the IGF2R/cation-independent mannose-6-phosphate receptor mechanism and biological outcomes.Q37404002
Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma.Q37407113
Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer.Q37589161
Biology and significance of signalling pathways activated by IGF-II.Q37963987
P433issue1
P304page(s)15-26
P577publication date2017-11-23
P1433published inFEBS Open BioQ27724062
P1476titleMatrix metalloproteinase-1 facilitates MSC migration via cleavage of IGF-2/IGFBP2 complex
P478volume8

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cites work (P2860)
Q92830126Manufacturing of primed mesenchymal stromal cells for therapy
Q57170076Mesenchymal Stem Cell Migration during Bone Formation and Bone Diseases Therapy

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