Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility

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Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1073/PNAS.1710401115
P932PMC publication ID5816140
P698PubMed publication ID29378942

P2093author name stringMelissa A Brown
Yuchen Yang
Abigail E Russi
Mark E Ebel
P2860cites workNatural history of multiple sclerosisQ22252934
Serum Testosterone in Women as Measured by an Automated Immunoassay and a RIA * Dr. Boudou responds for the authors of the article cited above:Q22306077
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokinesQ24294720
Transcription factor RORα is critical for nuocyte developmentQ24629126
IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.Q27315329
Sexual dimorphism in autoimmunityQ28080459
The glia-derived alarmin IL-33 orchestrates the immune response and promotes recovery following CNS injuryQ30300842
Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitisQ30510541
IL-33 Is Produced by Mast Cells and Regulates IgE-Dependent InflammationQ33651095
MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsionQ34106637
Group 2 innate lymphoid cells and CD4+ T cells cooperate to mediate type 2 immune response in miceQ34161017
Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cellsQ34442444
Mast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAEQ34546797
Testosterone treatment in multiple sclerosis: a pilot studyQ34628272
The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responsesQ34708854
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.Q34967101
The alarmin IL-33 promotes regulatory T-cell function in the intestineQ35116283
Sex-related factors in multiple sclerosis susceptibility and progressionQ35619427
Cutting edge: c-Kit signaling differentially regulates type 2 innate lymphoid cell accumulation and susceptibility to central nervous system demyelination in male and female SJL miceQ35691196
Interleukin-33 upregulation in peripheral leukocytes and CNS of multiple sclerosis patients.Q35785935
TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin RepairQ35972372
Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responsesQ36389520
Dimethyl fumarate treatment alters circulating T helper cell subsets in multiple sclerosisQ36429919
Inflammatory group 2 innate lymphoid cellsQ36468792
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammationQ36520874
Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathwayQ36522848
Cutting edge: Natural helper cells derive from lymphoid progenitorsQ36543519
Estradiol activates mast cells via a non-genomic estrogen receptor-alpha and calcium influxQ37015361
Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system.Q37126011
Neuroprotective effects of testosterone treatment in men with multiple sclerosisQ37634705
The changing demographic pattern of multiple sclerosis epidemiologyQ37732614
The influence of sex and gender on the immune responseQ37966544
Immunomodulation neuroprotection and remyelination - the fundamental therapeutic effects of glatiramer acetate: a critical reviewQ38220677
Contributing factors in multiple sclerosis and the female sex biasQ38249168
Group 2 innate lymphoid cells in diseaseQ38573631
Interleukin 33 is a guardian of barriers and a local alarminQ38702558
Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis.Q38872144
Interleukin-33 in health and diseaseQ38957840
T-bet-dependent NKp46+ innate lymphoid cells regulate the onset of TH17-induced neuroinflammation.Q40084014
Interleukin-33 is released in spinal cord and suppresses experimental autoimmune encephalomyelitis in miceQ40546690
Androgens alter the cytokine profile and reduce encephalitogenicity of myelin-reactive T cells.Q40981150
Gender differences in experimental autoimmune encephalomyelitis develop during the induction of the immune response to encephalitogenic peptidesQ41042211
An analysis of mast cell frequency in the rodent nervous system: numbers vary between different strains and can be reconstituted in mast cell-deficient miceQ41870845
Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammationQ42093185
Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: a role for neutrophil recruitment?Q42471779
Human mast cells express androgen receptors but treatment with testosterone exerts no influence on IgE-independent mast cell degranulation elicited by neuromuscular blocking agentsQ43275830
Type 2 innate lymphoid cells drive CD4+ Th2 cell responsesQ44613459
Androgens are protective in experimental autoimmune encephalomyelitis: implications for multiple sclerosis.Q44708828
Sex and strain differences in adult mouse cardiac repolarization: importance of androgensQ45203239
Middle-age male mice have increased severity of experimental autoimmune encephalomyelitis and are unresponsive to testosterone therapyQ45256192
Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. Th2-mediated suppression of autoimmune disease.Q46497979
Sex differences in experimental autoimmune encephalomyelitis in multiple murine strainsQ47774802
Gonadal hormones influence the immune response to PLP 139-151 and the clinical course of relapsing experimental autoimmune encephalomyelitisQ47969640
Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE.Q48240026
Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitisQ48249155
Dynamic changes in meningeal inflammation correspond to clinical exacerbations in a murine model of relapsing-remitting multiple sclerosisQ48373501
Interleukin-33 ameliorates ischemic brain injury in experimental stroke through promoting Th2 response and suppressing Th17 responseQ48415051
Interleukin-33 treatment reduces secondary injury and improves functional recovery after contusion spinal cord injury.Q48586737
Meningeal mast cell-T cell crosstalk regulates T cell encephalitogenicity.Q48631424
IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction.Q50870116
Testosterone therapy ameliorates experimental autoimmune encephalomyelitis and induces a T helper 2 bias in the autoantigen-specific T lymphocyte response.Q50949591
Sex differences in autoimmune diseaseQ55970264
Caspase-1, Caspase-8, and Calpain Are Dispensable for IL-33 Release by MacrophagesQ57273017
Tumor necrosis factor alpha immunoreactivity of rat peritoneal mast cell granules decreases during early secretion induced by compound 48/80: an ultrastructural immunogold morphometric analysisQ71087867
Ultrastructural immunogold localization of tumor necrosis factor-alpha to the cytoplasmic granules of rat peritoneal mast cells with rapid microwave fixationQ72182112
Up-regulation of IL-33 expression in various types of murine cells by IL-3 and IL-4Q83523966
Multiple sclerosisQ83785437
P407language of work or nameEnglishQ1860
P577publication date2018-01-29
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMale-specific IL-33 expression regulates sex-dimorphic EAE susceptibility

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