Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies?

scientific article published on 27 November 2017

Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/ANIE.201710407
P932PMC publication ID6280658
P698PubMed publication ID29178534

P50authorAlex DomlingQ73024340
P2093author name stringTad A Holak
Katarzyna Magiera-Mularz
Markella Konstantinidou
Tryfon Zarganes-Tzitzikas
P2860cites workB7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretionQ22010866
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Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary CancersQ27853176
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SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activationQ34331884
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Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells.Q42700822
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Safety of checkpoint inhibitors for cancer treatment: strategies for patient monitoring and management of immune-mediated adverse eventsQ47164715
Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.Q47842052
Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2.Q47999524
A case of fatal Guillain-Barre syndrome from anti-PD1 monoclonal antibody use.Q48194952
Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1.Q48278713
A cell culture model for T lymphocyte clonal anergyQ67299314
[Toxic epidermal necrolysis due to anti-PD1 treatment with fatal outcome]Q89209743
The immuno-oncology race: myths and emerging realitiesQ89919944
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)4840-4848
P577publication date2017-11-27
P1433published inAngewandte Chemie International EditionQ62023953
P1476titleImmune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies?
P478volume57

Reverse relations

cites work (P2860)
Q89510454Approaches to PET Imaging of Glioblastoma
Q92372610CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not?
Q92095247Challenges and strategies for next-generation bispecific antibody-based antitumor therapeutics
Q64273980Design and Synthesis of A PD-1 Binding Peptide and Evaluation of Its Anti-Tumor Activity
Q88643533Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40⁻CD154 Costimulatory Protein-Protein Interaction
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Q88922346Toward Small-Molecule Inhibition of Protein-Protein Interactions: General Aspects and Recent Progress in Targeting Costimulatory and Coinhibitory (Immune Checkpoint) Interactions

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