Omega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro

scientific article published on 16 February 2018

Omega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/IJMS19020586
P932PMC publication ID5855808
P698PubMed publication ID29462928

P50authorAngela Maria RizzoQ57006914
Roberta CassanoQ91299008
Sonia TrombinoQ39857815
P2093author name stringGabriella Calviello
Simona Serini
Paola Antonia Corsetto
P2860cites workFish oil LC-PUFAs do not affect blood coagulation parameters and bleeding manifestations: Analysis of 8 clinical studies with selected patient groups on omega-3-enriched medical nutrition.Q50713074
5-fluorouracil increases the chemopreventive potentials of resveratrol through DNA damage and MAPK signaling pathway in human colorectal cancer cells.Q53217998
Improved Stability and Enhanced Oral Bioavailability of Atorvastatin Loaded Stearic Acid Modified Gelatin Nanoparticles.Q53317454
The PTEN/PI3K/Akt and Wnt/β-catenin signaling pathways are involved in the inhibitory effect of resveratrol on human colon cancer cell proliferation.Q54212019
Trans-ferulic acid-based solid lipid nanoparticles and their antioxidant effect in rat brain microsomesQ59339525
Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cellsQ73220540
DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell linesQ84811677
Chemoprevention of colorectal cancerQ86373852
Plasma phospholipid fatty acids and prostate cancer risk in the SELECT trialQ24633239
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Docosahexaenoic Acid Induces Oxidative DNA Damage and Apoptosis, and Enhances the Chemosensitivity of Cancer CellsQ26741436
A Review of Nanoliposomal Delivery System for Stabilization of Bioactive Omega-3 Fatty AcidsQ26767211
Omega-3 Fatty Acids and Cancer Cell Cytotoxicity: Implications for Multi-Targeted Cancer TherapyQ26773056
Molecular therapy of colorectal cancer: progress and future directionsQ27005764
Old, new and emerging functions of caspasesQ27686885
Dietary and Lifestyle Factors Associated with Colorectal Cancer Risk and Interactions with Microbiota: Fiber, Red or Processed Meat and Alcoholic DrinksQ28077273
Extent of surgery in cancer of the colon: is more better?Q28084797
Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studiesQ30652483
Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathwaysQ33588231
Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients.Q34168543
Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancerQ34418424
Nutrients, foods, and colorectal cancer preventionQ34457478
Polyunsaturated fatty acids reduce fatty acid synthase and hydroxy-methyl-glutaryl CoA-reductase gene expression and promote apoptosis in HepG2 cell lineQ34541065
The role of n-3 polyunsaturated fatty acids in the prevention and treatment of breast cancerQ34578129
Fatty acid composition of plasma phospholipids and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and NutritionQ34876195
Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis-associated colorectal cancer acting on Notch signaling and gut microbiotaQ35133949
Polyunsaturated fatty acids trigger apoptosis of colon cancer cells through a mitochondrial pathwayQ36220680
Chemotherapy for Stage II Colon CancerQ36304759
Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferationQ36393513
Epigenetic regulation of colon cancer and intestinal stem cellsQ36736072
Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer.Q37364559
Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: the role of inflammation.Q37697523
Dietary ω-3 Polyunsaturated Fatty Acids Inhibit Tumor Growth in Transgenic ApcMin/+ Mice, Correlating with CB1 Receptor Up-RegulationQ37728998
Modulation of Ras/ERK and Phosphoinositide Signaling by Long-Chain n-3 PUFA in Breast Cancer and Their Potential Complementary Role in Combination with Targeted DrugsQ37729599
Dietary n-3 polyunsaturated fatty acids and the paradox of their health benefits and potential harmful effects.Q37929141
Molecularly targeted therapy: toxicity and quality of life considerations in advanced colorectal cancerQ38153444
Colon cancer: cancer stem cells markers, drug resistance and treatmentQ38280180
Docosahexaenoic acid regulated genes and transcription factors inducing apoptosis in human colon cancer cellsQ38294641
Down-regulation of malignant potential by alpha linolenic acid in human and mouse colon cancer cellsQ38432718
Long-chain n-3 PUFA against breast and prostate cancer: Which are the appropriate doses for intervention studies in animals and humans?Q38432847
Epigenetic regulation of gene expression and M2 macrophage polarization as new potential omega-3 polyunsaturated fatty acid targets in colon inflammation and cancerQ38701709
α-Tocopheryl linolenate solid lipid nanoparticles for the encapsulation, protection, and release of the omega-3 polyunsaturated fatty acid: in vitro anti-melanoma activity evaluation.Q38725611
Long chain n-3 polyunsaturated fatty acids increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt and PKCε/δ-induced ERK pathways.Q38798659
Changes in Red Blood Cell membrane lipid composition: A new perspective into the pathogenesis of PKAN.Q38812940
α-Linolenic Acid Reduces Growth of Both Triple Negative and Luminal Breast Cancer Cells in High and Low Estrogen EnvironmentsQ38857833
Solid lipid nanoparticles for antifungal drugs delivery for topical applicationsQ38943050
Preparation, characterization and in vitro activities evaluation of solid lipid nanoparticles based on PEG-40 stearate for antifungal drugs vaginal deliveryQ38977027
Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitroQ39153723
DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and β-catenin nuclear translocationQ39449462
Resveratrol potentiates the cytotoxic oxidative stress induced by chemotherapy in human colon cancer cellsQ39484885
How plausible is the use of dietary n-3 PUFA in the adjuvant therapy of cancer?Q39771420
Growth-inhibitory and proapoptotic effects of alpha-linolenic acid on estrogen-positive breast cancer cellsQ39805465
Stearyl ferulate-based solid lipid nanoparticles for the encapsulation and stabilization of beta-carotene and alpha-tocopherolQ39857675
Differential induction of apoptosis and inhibition of the PI3-kinase pathway by saturated, monounsaturated and polyunsaturated fatty acids in a colon cancer cell modelQ39941107
Docosahexaenoic acid induces apoptosis in lung cancer cells by increasing MKP-1 and down-regulating p-ERK1/2 and p-p38 expressionQ39953939
Trypan Blue Exclusion Test of Cell Viability.Q40924988
Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancerQ41841905
Highly purified eicosapentaenoic acid as free fatty acids strongly suppresses polyps in Apc(Min/+) mice.Q41954579
Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention.Q42378404
Resveratrol inhibits proliferation, angiogenesis and induces apoptosis in colon cancer cells: calorie restriction is the force to the cytotoxicityQ42712255
Effects of components present in flaxseed on human colon adenocarcinoma Caco-2 cells: Possible mechanisms of flaxseed on colon cancer development in animals.Q42719105
Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposisQ43116331
Prostate cancer vs hyperplasia: relationships with prostatic and adipose tissue fatty acid compositionQ44080769
n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathwayQ45052756
Docosahexaenoic acid enhances the susceptibility of human colorectal cancer cells to 5-fluorouracilQ45057792
Effects of stearic acid on plasma lipid and lipoproteins in humansQ46943985
Long-chain omega-3 fatty acids and cancer: any cause for concern?Q47786878
MFSD2A Promotes Endothelial Generation of Inflammation-Resolving Lipid Mediators and Reduces Colitis in MiceQ47925587
VitD3-loaded solid lipid nanoparticles: stability, cytotoxicity and cytokine levelsQ47960052
Stearic acid based, systematically designed oral lipid nanoparticles for enhanced brain delivery of dimethyl fumarateQ47990775
A novel bioactive derivative of eicosapentaenoic acid (EPA) suppresses intestinal tumor development in ApcΔ14/+ miceQ48580870
Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2.Q50336851
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
P577publication date2018-02-16
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleOmega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro
P478volume19

Reverse relations

cites work (P2860)
Q99711232Allergy Modulation by N-3 Long Chain Polyunsaturated Fatty Acids and Fat Soluble Nutrients of the Mediterranean Diet
Q92989453Anti-Irritant and Anti-Inflammatory Effects of DHA Encapsulated in Resveratrol-Based Solid Lipid Nanoparticles in Human Keratinocytes
Q64056096Antineuroinflammatory Activities and Neurotoxicological Assessment of Curcumin Loaded Solid Lipid Nanoparticles on LPS-Stimulated BV-2 Microglia Cell Models
Q64063052Application of Solid Lipid Nanoparticles to Improve the Efficiency of Anticancer Drugs
Q57070261Colorectal cancer combination therapy using drug and gene co-delivered, targeted poly(ethylene glycol)-ε-poly(caprolactone) nanocarriers
Q92422565Evaluation of the Influence of Process Parameters on the Properties of Resveratrol-Loaded NLC Using 22 Full Factorial Design
Q92344320Lipid Reshaping and Lipophagy Are Induced in a Modeled Ischemia-Reperfusion Injury of Blood Brain Barrier
Q64989553Lipid-Based Nanoparticles: Application and Recent Advances in Cancer Treatment.
Q64097121Nanomedicine-based formulations containing ω-3 polyunsaturated fatty acids: potential application in cardiovascular and neoplastic diseases
Q90434725Nutraceuticals' Novel Formulations: The Good, the Bad, the Unknown and Patents Involved
Q59882706Omega-3 polyunsaturated fatty acids as adjuvant therapy of colorectal cancer
Q90410010Omega-3PUFA Attenuates MNU-Induced Colorectal Cancer in Rats by Blocking PI3K/AKT/Bcl-2 Signaling
Q94452892Pumpkin Oil-Based Nanostructured Lipid Carrier System for Antiulcer Effect in NSAID-Induced Gastric Ulcer Model in Rats

Search more.