High glucose enhances the metastatic potential of tongue squamous cell carcinoma via the PKM2 pathway

scientific article published on 4 December 2017

High glucose enhances the metastatic potential of tongue squamous cell carcinoma via the PKM2 pathway is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.22907
P932PMC publication ID5762358
P698PubMed publication ID29340090

P2093author name stringWei Wang
Zhonghua Liu
Xiaofeng Zhou
Zhiyuan Lu
Anxun Wang
Jingjing Sun
Qianting He
Zujian Chen
Jinsong Hou
Wangxiang Yan
Yisen Shao
P2860cites workHexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondriaQ24595940
Evidence for DNA damage as a biological link between diabetes and cancerQ27001226
Global estimates of the prevalence of diabetes for 2010 and 2030Q29547218
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growthQ29547680
Deregulation of manganese superoxide dismutase (SOD2) expression and lymph node metastasis in tongue squamous cell carcinomaQ33629430
Proteomic based identification of manganese superoxide dismutase 2 (SOD2) as a metastasis marker for oral squamous cell carcinoma.Q33932201
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Survival among patients with pancreatic cancer and long-standing or recent-onset diabetes mellitusQ34716541
Bmi1 drives stem-like properties and is associated with migration, invasion, and poor prognosis in tongue squamous cell carcinomaQ34780881
Down-regulation of tumor suppressor MTUS1/ATIP is associated with enhanced proliferation, poor differentiation and poor prognosis in oral tongue squamous cell carcinomaQ35712864
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Manganese superoxide dismutase induces migration and invasion of tongue squamous cell carcinoma via H2O2-dependent Snail signalingQ36040743
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Deregulation of the miR-222-ABCG2 regulatory module in tongue squamous cell carcinoma contributes to chemoresistance and enhanced migratory/invasive potentialQ36689033
SOD2 deregulation enhances migration, invasion and has poor prognosis in salivary adenoid cystic carcinomaQ36903196
Diabetes and oral oncogenesisQ37069075
Hyperglycemia Promotes the Epithelial-Mesenchymal Transition of Pancreatic Cancer via Hydrogen PeroxideQ37084377
High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2.Q37109882
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High glucose promotes tumor invasion and increases metastasis-associated protein expression in human lung epithelial cells by upregulating heme oxygenase-1 via reactive oxygen species or the TGF-β1/PI3K/Akt signaling pathwayQ38911827
SOD2 is a C-myc target gene that promotes the migration and invasion of tongue squamous cell carcinoma involving cancer stem-like cellsQ38921132
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Excess glucose induces hypoxia-inducible factor-1α in pancreatic cancer cells and stimulates glucose metabolism and cell migrationQ39200208
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Pyruvate kinase M2 deregulation enhances the metastatic potential of tongue squamous cell carcinomaQ41844362
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Deregulation of Bmi-1 is associated with enhanced migration, invasion and poor prognosis in salivary adenoid cystic carcinomaQ87645868
P433issue67
P407language of work or nameEnglishQ1860
P921main subjecttongue squamous cell carcinomaQ28757362
metastatic potentialQ122615215
P304page(s)111770-111779
P577publication date2017-12-04
P1433published inOncotargetQ1573155
P1476titleHigh glucose enhances the metastatic potential of tongue squamous cell carcinoma via the PKM2 pathway
P478volume8