Retinal genes are differentially expressed in areas of primary versus secondary degeneration following partial optic nerve injury

scientific article published on 9 February 2018

Retinal genes are differentially expressed in areas of primary versus secondary degeneration following partial optic nerve injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0192348
P932PMC publication ID5806857
P698PubMed publication ID29425209

P50authorAlex W. HewittQ61809768
Alan R HarveyQ89244408
Melinda FitzgeraldQ42339698
Phillip E. MeltonQ40806405
P2093author name stringChrisna J LeVaillant
Carole A Bartlett
Wissam Chiha
P2860cites workSimilarities and differences between primary and secondary degeneration of the optic nerve and the effect of minocycline.Q54392899
Early in vivo changes in calcium ions, oxidative stress markers, and ion channel immunoreactivity following partial injury to the optic nerveQ60242452
Unilateral injury to the adult rat optic nerve causes multiple cellular responses in the contralateral siteQ74459228
Transformation of adult retina from the regenerative to the axonogenesis state activates specific genes in various subsets of neurons and glial cellsQ79320495
Early events of secondary degeneration after partial optic nerve transection: an immunohistochemical studyQ43255973
Intense light exposure changes the crystallin content in retinaQ44317734
Differential Temporal and Spatial Expression of Immediate Early Genes in Retinal Neurons after Ischemia–Reperfusion InjuryQ44417324
A model to study differences between primary and secondary degeneration of retinal ganglion cells in rats by partial optic nerve transection.Q44526862
Retinal oxidative stress induced by high intraocular pressureQ45071741
The role of alphaA- and alphaB-crystallins in the survival of retinal ganglion cells after optic nerve axotomyQ46091706
Secondary degeneration of the optic nerve following partial transection: the benefits of lomerizineQ46177834
Immediate upregulation of proteins belonging to different branches of the apoptotic cascade in the retina after optic nerve transection and optic nerve crushQ46384814
Gene expression changes in the retina following optic nerve transection.Q46588535
Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucomaQ46667386
Reactive species and oxidative stress in optic nerve vulnerable to secondary degeneration.Q46879402
Microarray analysis of retinal gene expression in the DBA/2J model of glaucomaQ46966279
Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressureQ47903438
Modulation of alpha and beta crystallin expression in rat retinas with ocular hypertension-induced ganglion cell degenerationQ48265937
Changes in mRNA expression of class 3 semaphorins and their receptors in the adult rat retino-collicular system after unilateral optic nerve injuryQ48302537
Degeneration of spared axons following partial white matter lesion: implications for optic nerve neuropathiesQ48392911
Transient increase of manganese-superoxide dismutase in remote brain areas after focal photothrombotic cortical lesionQ48554194
Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengersQ28585106
limma powers differential expression analyses for RNA-sequencing and microarray studiesQ29617988
Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade.Q30485076
Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanismsQ33308449
Mechanism of retinal ganglion cells death in secondary degeneration of the optic nerveQ33516992
Temporal changes in gene expression after injury in the rat retinaQ33652444
Cell death mechanisms and modulation in traumatic brain injuryQ33740409
Calcium, ischemia and excitotoxicity.Q34099560
Large-scale gene function analysis with the PANTHER classification systemQ34358449
Degeneration of axotomized retinal ganglion cells as a model for neuronal apoptosis in the central nervous system - molecular death and survival pathways.Q34704823
Paranode Abnormalities and Oxidative Stress in Optic Nerve Vulnerable to Secondary Degeneration: Modulation by 670 nm Light TreatmentQ34805453
Lycium barbarum (wolfberry) reduces secondary degeneration and oxidative stress, and inhibits JNK pathway in retina after partial optic nerve transection.Q34873489
Secondary retinal ganglion cell death and the neuroprotective effects of the calcium channel blocker lomerizineQ34983365
Retinal gene expression changes related to IOP exposure and axonal loss in DBA/2J miceQ35908952
A prospective study of secondary degeneration following subcortical infarction using diffusion tensor imagingQ36143851
Astrocyte dysfunction in neurological disorders: a molecular perspectiveQ36404127
The mitochondrial permeability transition from in vitro artifact to disease targetQ36464595
Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crushQ36717830
Attenuated glial reactions and photoreceptor degeneration after retinal detachment in mice deficient in glial fibrillary acidic protein and vimentin.Q37037237
The mitochondrial permeability transition pore: a molecular target for amyotrophic lateral sclerosis therapyQ37466115
Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injuryQ37602939
Longitudinal Assessments of Normal and Perilesional Tissues in Focal Brain Ischemia and Partial Optic Nerve Injury with Manganese-enhanced MRI.Q37661015
Neuronal injury-inducible gene is synergistically regulated by ATF3, c-Jun, and STAT3 through the interaction with Sp1 in damaged neuronsQ40025578
Ionic dependence of glutamate neurotoxicityQ41343328
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)e0192348
P577publication date2018-02-09
P1433published inPLOS OneQ564954
P1476titleRetinal genes are differentially expressed in areas of primary versus secondary degeneration following partial optic nerve injury
P478volume13

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cites work (P2860)
Q90119612Quantitative profiling of regional protein expression in rat retina after partial optic nerve transection using fluorescence difference two‑dimensional gel electrophoresis
Q64096330Voluntary running delays primary degeneration in rat retinas after partial optic nerve transection

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