Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC.

scientific article published on 9 February 2018

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1100915290
P356DOI10.1186/S40478-018-0508-2
P2888exact matchhttps://scigraph.springernature.com/pub.10.1186/s40478-018-0508-2
P932PMC publication ID5806364
P698PubMed publication ID29422107

P50authorBernardino F. GhettiQ56863342
Douglas R. GalaskoQ67228424
Byron CaugheyQ88511201
Katrina J CampbellQ88893396
P2093author name stringAndrew G Hughson
Christina D Orrù
Bradley R Groveman
Gianluigi Zanusso
Lynne D Raymond
Jiri Safar
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Advanced tests for early and accurate diagnosis of Creutzfeldt-Jakob diseaseQ31095751
Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion StrainsQ33457447
The neuropathology of probable Alzheimer disease and mild cognitive impairmentQ33616561
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Prospective validation of consensus criteria for the diagnosis of dementia with Lewy bodies.Q33864626
Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic studyQ34043770
Synucleinopathies: clinical and pathological implicationsQ34140347
Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.Q34161515
A test for Creutzfeldt-Jakob disease using nasal brushingsQ34293962
MDS clinical diagnostic criteria for Parkinson's diseaseQ34498274
Early detection of abnormal prion protein in genetic human prion diseases now possible using real-time QUIC assayQ34571438
Quantitative assessment of prion infectivity in tissues and body fluids by real-time quaking-induced conversionQ34720803
Prion disease blood test using immunoprecipitation and improved quaking-induced conversionQ35006294
Characteristic CSF prion seeding efficiency in humans with prion diseasesQ35024691
Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluidQ35038237
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Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversionQ35960528
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Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies.Q37307515
Establishing quantitative real-time quaking-induced conversion (qRT-QuIC) for highly sensitive detection and quantification of PrPSc in prion-infected tissues.Q37485455
Primary progressive aphasia: clinicopathological correlationsQ37688883
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Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid SamplesQ38784162
Duration and Pathologic Correlates of Lewy Body DiseaseQ39004053
Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC.Q40196812
Diagnostic and prognostic value of human prion detection in cerebrospinal fluidQ40433329
Early detection of chronic wasting disease prions in urine of pre-symptomatic deer by real-time quaking-induced conversion assay.Q41900931
Influence of Alzheimer pathology on clinical diagnostic accuracy in dementia with Lewy bodiesQ42442006
Sequence determinants regulating fibrillation of human alpha-synucleinQ46762879
Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid.Q48405878
Why does Coomassie Brilliant Blue R interact differently with different proteins? A partial answer.Q50914743
A Test for Creutzfeldt–Jakob Disease Using Nasal BrushingsQ59505789
Formation and Characterization of α-Synuclein OligomersQ86433702
P433issue1
P921main subjectcerebrospinal fluidQ54196
SynucleinQ24767155
RT-QuICQ64157236
P304page(s)7
P577publication date2018-02-09
P1433published inActa Neuropathologica CommunicationsQ27724912
P1476titleRapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC.
P478volume6

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