Emerging nonmetabolic functions of skin fat.

scientific article published on 12 January 2018

Emerging nonmetabolic functions of skin fat. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NRENDO.2017.162
P932PMC publication ID6042872
P698PubMed publication ID29327704

P2093author name stringMaksim V Plikus
Christian F Guerrero-Juarez
P2860cites workNerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cellsQ42728761
Hedgehog signaling plays a conserved role in inhibiting fat formationQ42806335
Characterization of the adipocyte cellular lineage in vivoQ43077735
C/EBPalpha identifies differentiating preadipocytes around hair follicles in foetal and neonatal rat and mouse skin.Q44851857
Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.Q46673942
Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia.Q48176413
Repeal and Replace: Adipocyte Regeneration in Wound RepairQ50445749
WNT and DKK determine hair follicle spacing through a reaction-diffusion mechanismQ51929587
PDGF isoforms induce and maintain anagen phase of murine hair folliclesQ54332374
Observations on the Remarkable (and Mysterious) Wound-Healing Process of the Bottlenose DolphinQ56773005
IGF-I Signalling Controls the Hair Growth Cycle and the Differentiation of Hair ShaftsQ56784822
Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total DeletionQ59282117
Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the SkinQ63406949
Some particularities of human skin and the skin of nonhuman primatesQ70619359
Expression of transforming growth factor beta isoforms and their receptors during hair growth phases in miceQ71663246
Changes in the skin in relation to the hair growth cycleQ73150744
Control of murine hair follicle regression (catagen) by TGF-beta1 in vivoQ73615626
Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and CyclingQ73775315
Hair cycle-dependent changes in the gene expression and protein content of transforming factor β1 and β3 in murine skinQ73815218
Fat in skin of the mouse during cycles of hair growthQ74027181
Matrix metalloproteinase inhibition impairs adipose tissue development in miceQ77743242
Dermatology: the eccrine sweat glandsQ79061242
Comprehensive analysis of FGF and FGFR expression in skin: FGF18 is highly expressed in hair follicles and capable of inducing anagen from telogen stage hair folliclesQ81688936
Identification of white adipocyte progenitor cells in vivoQ82206003
Inhibition of adipogenesis by Wnt signalingQ22254771
Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicleQ24595260
Adipocyte extracellular matrix composition, dynamics and role in obesityQ24627461
Molecular dissection of mesenchymal-epithelial interactions in the hair follicleQ24815112
Defining dermal adipose tissueQ26861455
Hair cycle regulation of Hedgehog signal receptionQ28185267
Requirement of fibroblast growth factor 10 in development of white adipose tissueQ28504753
Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicleQ28506996
Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesisQ28591573
Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesisQ29615762
Dynamics between Stem Cells, Niche, and Progeny in the Hair FollicleQ30498374
Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem CellsQ30512824
Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factorsQ30576465
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironmentQ33701168
Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironmentQ33743676
Transcriptional control of preadipocyte determination by Zfp423.Q33753951
Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone RegenerationQ33765723
Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis.Q33841907
Regenerative hair waves in aging mice and extra-follicular modulators follistatin, dkk1, and sfrp4Q33916800
Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat depositionQ34002255
Syndecan-1 is required to maintain intradermal fat and prevent cold stressQ34015240
The growth of hair follicles and its relation to the adjacent dermal structuresQ34035349
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fateQ34092765
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growthQ34147708
A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stagesQ34301829
Capturing and profiling adult hair follicle stem cells.Q34306293
Distinct fibroblast lineages determine dermal architecture in skin development and repair.Q34391786
Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicleQ34405808
Hair follicle predetermination.Q34420916
Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysisQ34515576
Fetal development of subcutaneous white adipose tissue is dependent on Zfp423.Q34550053
Independent stem cell lineages regulate adipose organogenesis and adipose homeostasisQ34605960
Wnt-dependent de novo hair follicle regeneration in adult mouse skin after woundingQ34629066
Development of the mouse dermal adipose layer occurs independently of subcutaneous adipose tissue and is marked by restricted early expression of FABP4.Q34652284
Cyclic dermal BMP signalling regulates stem cell activation during hair regenerationQ34737529
LRP5 regulates human body fat distribution by modulating adipose progenitor biology in a dose- and depot-specific fashion.Q35064400
Rapid depot-specific activation of adipocyte precursor cells at the onset of obesityQ35235848
Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissueQ35377599
Wnt7b is an important intrinsic regulator of hair follicle stem cell homeostasis and hair follicle cycling.Q35431848
Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell poolQ35688878
Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitorsQ35755610
Analysis of apoptosis during hair follicle regression (catagen)Q35764942
Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair CyclingQ35819382
A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasisQ35981284
BMP signaling in the control of skin development and hair follicle growth.Q35992960
Molecular principles of hair follicle induction and morphogenesisQ36043778
Obesity-induced remodeling of the adipose tissue elastin network is independent of the metalloelastase MMP-12.Q36068555
Identification of stem cell populations in sweat glands and ducts reveals roles in homeostasis and wound repairQ36176254
Dermal white adipose tissue: a new component of the thermogenic responseQ36197802
Principles and mechanisms of regeneration in the mouse model for wound-induced hair follicle neogenesisQ36198602
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA.Q36324810
Adipocyte-derived endotrophin promotes malignant tumor progressionQ36357889
Dermal Adipocytes: From Irrelevance to Metabolic Targets?Q36421885
Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineagesQ36548726
WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.Q36616934
A Guide to Studying Human Hair Follicle Cycling In VivoQ36669777
Intradermal adipocytes mediate fibroblast recruitment during skin wound healingQ36682969
Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot?Q36723199
Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk.Q36895502
β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular DermisQ36922404
Marrow Adipose Tissue: Trimming the FatQ36923810
Complex hair cycle domain patterns and regenerative hair waves in living rodentsQ37038427
Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.Q37110569
Ebf1-dependent control of the osteoblast and adipocyte lineagesQ37133899
Skin aging: are adipocytes the next target?Q37194238
Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPARγ.Q37319591
Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activityQ37382487
Macroenvironmental regulation of hair cycling and collective regenerative behaviorQ37406287
Nfatc1 orchestrates aging in hair follicle stem cellsQ37409450
Hair follicles' transit-amplifying cells govern concurrent dermal adipocyte production through Sonic HedgehogQ37416659
The Role of Adipocytes in Tissue Regeneration and Stem Cell NichesQ37505068
What we talk about when we talk about fat.Q37601812
Spatiotemporal antagonism in mesenchymal-epithelial signaling in sweat versus hair fate decisionQ37677008
The dermal papilla: an instructive niche for epithelial stem and progenitor cells in development and regeneration of the hair follicleQ38225354
Hair cycle control by leptin as a new anagen inducerQ38311195
Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiationQ38358677
Skin morphology and its role in thermoregulation in mole-rats, Heterocephalus glaber and Cryptomys hottentotusQ38476228
A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterningQ38684631
Distinct Fibroblasts in the Papillary and Reticular Dermis: Implications for Wound HealingQ39021351
Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling AxisQ39286426
Some histological aspects of the palmar digital pads in the vervet monkeyQ39350143
Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway.Q39449375
TLE3 is a dual-function transcriptional coregulator of adipogenesisQ39565699
Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene ProgramQ39726997
Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles.Q39892897
Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiationQ40787603
Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehogQ40851834
White fat progenitor cells reside in the adipose vasculature.Q41145314
Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermisQ41390151
Human Skin Fibroblasts Derived from Papillary and Reticular Dermis: Differences in Growth Potential in VitroQ41521539
Innate immunity. Dermal adipocytes protect against invasive Staphylococcus aureus skin infectionQ41566039
Unravelling hair follicle–adipocyte communicationQ41849112
Epithelial Wnt ligand secretion is required for adult hair follicle growth and regenerationQ41865262
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasisQ41887923
Regeneration of fat cells from myofibroblasts during wound healing.Q42165518
The Role of IGF-I in Human Skin and its Appendages: Morphogen as Well as Mitogen?Q42448465
Subcutaneous abdominal adipose tissue subcompartments: potential role in rosiglitazone effectsQ42448720
The influence of the hair cycle on the thickness of mouse skinQ42458934
P433issue3
P304page(s)163-173
P577publication date2018-01-12
P1433published inNature Reviews EndocrinologyQ2079257
P1476titleEmerging nonmetabolic functions of skin fat.
P478volume14

Reverse relations

cites work (P2860)
Q92254959Caveolin as a Universal Target in Dermatology
Q92505558Choreographing Immunity in the Skin Epithelial Barrier
Q90020708Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice
Q90663139Diet and Skin Aging-From the Perspective of Food Nutrition
Q90324867Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration
Q91974983Functional histology of the skin in the subterranean African giant mole-rat: thermal windows are determined solely by pelage characteristics
Q58617304Hyaluronidase inhibits reactive adipogenesis and inflammation of colon and skin
Q90356811Isolation and Characterization of Cutaneous Epithelial Stem Cells
Q64251637Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells
Q98623653Obesity and ethnicity alter gene expression in skin
Q92826446Short exposure to cold atmospheric plasma induces senescence in human skin fibroblasts and adipose mesenchymal stromal cells
Q92537912Specific Biological Features of Adipose Tissue, and Their Impact on HIV Persistence
Q90592501The Role of Immature and Mature Adipocytes in Hair Cycling

Search more.