Ca(2+)-evoked serotonin secretion by parafollicular cells: roles in signal transduction of phosphatidylinositol 3'-kinase, and the gamma and zeta isoforms of protein kinase C.

scientific article published in February 2000

Ca(2+)-evoked serotonin secretion by parafollicular cells: roles in signal transduction of phosphatidylinositol 3'-kinase, and the gamma and zeta isoforms of protein kinase C. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.20-04-01365.2000
P932PMC publication ID6772377
P698PubMed publication ID10662827

P50authorMichael D. GershonQ6829630
P2093author name stringK Liu
H Tamir
S Hsiung
M Adlersberg
T Sacktor
P2860cites workPurification and characterization of phosphoinositide 3-kinase from rat liverQ24311865
Persistent activation of the zeta isoform of protein kinase C in the maintenance of long-term potentiationQ24561596
Nucleolin is a protein kinase C-zeta substrate. Connection between cell surface signaling and nucleus in PC12 cellsQ28255775
Sequence and expression of a metabotropic glutamate receptorQ28280066
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1Q28283323
Localization of protein kinases by anchoring proteins: a theme in signal transductionQ28299903
Protein kinase C and lipid signaling for sustained cellular responsesQ28300819
Regulation of protein kinase C zeta by PI 3-kinase and PDK-1Q28567633
Protein kinase C-zeta and phosphoinositide-dependent protein kinase-1 are required for insulin-induced activation of ERK in rat adipocytesQ73083177
Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptideQ73717928
Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transportQ28570514
Protein kinase C: structure, function, and regulationQ28618608
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)Q28640016
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Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cellsQ33884851
Induction of a neural phenotype in a serotonergic endocrine cell derived from the neural crestQ34173484
Ultrastructural localization of calcitonin, somatostatin and serotonin in parafollicular cells of rat thyroidQ34248617
Separation of dissociated thyroid follicular and parafollicular cells: association of serotonin binding protein with parafollicular cellsQ34281857
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.Q34290591
Transfected m2 muscarinic acetylcholine receptors couple to G alpha i2 and G alpha i3 in Chinese hamster ovary cells. Activation and desensitization of the phospholipase C signaling pathwayQ34361646
Thyrotropin induces the acidification of the secretory granules of parafollicular cells by increasing the chloride conductance of the granular membraneQ34409614
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The extracellular calcium receptorQ40380552
Phosphatidylinositol 3-kinaseQ40702617
Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytesQ41103820
IL-2 signaling controls actin organization through Rho-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-zetaQ41127643
ATP-dependent uptake of 5-hydroxytryptamine by secretory granules isolated from thyroid parafollicular cellsQ41151954
Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulationQ41191785
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Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunitQ42066856
Deletion analysis of protein kinase C inactivation by calphostin C.Q42067382
Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.Q42067413
Two types of phosphatidylinositol 3-kinase from bovine thymus. Monomer and heterodimer formQ42131723
Purification and characterization of Gbetagamma-responsive phosphoinositide 3-kinases from pig platelet cytosolQ42438790
Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.Q42558480
The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C.Q42802927
Phosphorylation of Sendai virus phosphoprotein by cellular protein kinase C zetaQ45762362
A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphosphate formation in chemoattractant-stimulated human neutrophilsQ46101870
Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cellQ46488580
A G-protein beta gamma-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosolQ48104952
Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.Q48347794
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Localization of calcium receptor mRNA in the adult rat central nervous system by in situ hybridizationQ50112165
Acidification of serotonin-containing secretory vesicles induced by a plasma membrane calcium receptorQ50113258
The lipid products of phosphoinositide 3-kinase contribute to regulation of cholangiocyte ATP and chloride transportQ57220313
A synthetic peptide of the pseudosubstrate domain of protein kinase C blocks cytoplasmic alkalinization during activation of the sea urchin eggQ68859438
Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase CQ69059319
Serotonin-storing secretory granules from thyroid parafollicular cellsQ69475392
Bacterial lipopolysaccharide induces the association and coordinate activation of p53/56lyn and phosphatidylinositol 3-kinase in human monocytesQ70890756
Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinaseQ72237914
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1365-1373
P577publication date2000-02-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleCa(2+)-evoked serotonin secretion by parafollicular cells: roles in signal transduction of phosphatidylinositol 3'-kinase, and the gamma and zeta isoforms of protein kinase C
P478volume20

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cites work (P2860)
Q43948434Altered dendritic development of cerebellar Purkinje cells in slice cultures from protein kinase Cgamma-deficient mice
Q43694305Atypical protein kinase C is a novel mediator of dopamine-enhanced firing in nucleus accumbens neurons.
Q44376538Calcium receptor-induced serotonin secretion by parafollicular cells: role of phosphatidylinositol 3-kinase-dependent signal transduction pathways.
Q31925660Effects of wortmannin upon the late stages of the secretory pathway of AtT-20 cells
Q44762662Enteric dopaminergic neurons: definition, developmental lineage, and effects of extrinsic denervation.
Q36118080Essential role of protein kinase C zeta in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP.
Q28588075Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters
Q24540292Mu and kappa opioid receptors activate ERK/MAPK via different protein kinase C isoforms and secondary messengers in astrocytes
Q42588236Whereas short-term facilitation is presynaptic, intermediate-term facilitation involves both presynaptic and postsynaptic protein kinases and protein synthesis

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