The Impact of Biologics and Tofacitinib on Cardiovascular Risk Factors and Outcomes in Patients with Rheumatic Disease: A Systematic Literature Review

scientific article published on 9 January 2018

The Impact of Biologics and Tofacitinib on Cardiovascular Risk Factors and Outcomes in Patients with Rheumatic Disease: A Systematic Literature Review is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S40264-017-0628-9
P932PMC publication ID5938314
P698PubMed publication ID29318514

P2093author name stringErnest Choy
Blerina Kola
Ryan DeMasi
Sadiq Lula
Michael Nurmohamed
Paola Accossato
P2860cites workComparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION studyQ24630541
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 updateQ26859134
The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventionsQ27860564
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statementQ27860868
Treatment of rheumatoid arthritis with etanercept with reference to disease-modifying anti-rheumatic drugs: long-term safety and survival using prospective, observational dataQ30680371
Effects of infliximab treatment on lipoprotein profile in patients with rheumatoid arthritis and ankylosing spondylitisQ82847957
Augmentation index in patients with rheumatoid arthritis and ankylosing spondylitis treated with infliximabQ82930139
No significant change in arterial stiffness in RA after 6 months and 1 year of rituximab treatmentQ83430670
Venous and arterial thromboembolic events in adalimumab-treated patients with antiadalimumab antibodies: a case series and cohort studyQ83753675
TNF-alpha antagonist survival rate in a cohort of rheumatoid arthritis patients observed under conditions of standard clinical practiceQ84565491
Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritisQ84751886
Tocilizumab increases EPC regeneration in rheumatoid arthritisQ85313522
Etanercept improves lipid profile and oxidative stress measures in patients with juvenile idiopathic arthritisQ86520150
Tofacitinib versus methotrexate in rheumatoid arthritisQ88103514
???Q28295371
Improvement of lipid profile is accompanied by atheroprotective alterations in high-density lipoprotein composition upon tumor necrosis factor blockade: a prospective cohort study in ankylosing spondylitis.Q33436848
74-week follow-up of safety of infliximab in patients with refractory rheumatoid arthritisQ34027648
Modifications in lipid levels are independent of serum TNF-α in rheumatoid arthritis: results of an observational 24-week cohort study comparing patients receiving etanercept plus methotrexate or methotrexate as monotherapyQ34162072
Infliximab, an anti-TNF-alpha agent, improves left atrial abnormalities in patients with rheumatoid arthritis: preliminary resultsQ34219694
HDL protein composition alters from proatherogenic into less atherogenic and proinflammatory in rheumatoid arthritis patients responding to rituximabQ34270268
2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid ArthritisQ34500921
Efficacy and tolerability of tocilizumab in rheumatoid arthritis patients seen in daily clinical practice in Japan: results from a retrospective study (REACTION study).Q34768442
The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placeboQ34989826
Adverse events of anti-tumor necrosis factor α therapy in ankylosing spondylitisQ35170882
Venous thrombotic events are not increased in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register.Q35200354
Tocilizumab in rheumatoid arthritis: a case study of safety evaluations of a large postmarketing data set from multiple data sourcesQ35318027
Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled studyQ35352554
The global challenges and opportunities in the practice of rheumatology: white paper by the World Forum on Rheumatic and Musculoskeletal DiseasesQ35533763
Postmarketing surveillance of tocilizumab for rheumatoid arthritis in Japan: interim analysis of 3881 patientsQ35540000
Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trialQ35605487
Increased disease activity is associated with a deteriorated lipid profile in patients with ankylosing spondylitisQ35638180
The Impact of Newer Biological Disease Modifying Anti-Rheumatic Drugs on Cardiovascular Risk Factors: A 12-Month Longitudinal Study in Rheumatoid Arthritis Patients Treated with Rituximab, Abatacept and TociliziumabQ35675593
Heart failure in rheumatoid arthritis: rates, predictors, and the effect of anti-tumor necrosis factor therapyQ35676074
Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing SpondylitisQ35877149
Changes in lipid profile during infliximab and corticosteroid treatment in rheumatoid arthritisQ35954510
Anti-TNF-alpha-adalimumab therapy is associated with persistent improvement of endothelial function without progression of carotid intima-media wall thickness in patients with rheumatoid arthritis refractory to conventional therapyQ36151574
Adalimumab: long-term safety in 23 458 patients from global clinical trials in rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis and Crohn's diseaseQ36677345
Heart failure among younger rheumatoid arthritis and Crohn's patients exposed to TNF-alpha antagonistsQ36742762
Efficacy and safety of tofacitinib as monotherapy in Japanese patients with active rheumatoid arthritis: a 12-week, randomized, phase 2 studyQ36761766
Macrolide antibiotics and the risk of ventricular arrhythmia in older adultsQ36808701
Long-term safety of rituximab in rheumatoid arthritis: 9.5-year follow-up of the global clinical trial programme with a focus on adverse events of interest in RA patientsQ37130018
A general framework for the evaluation of clinical trial qualityQ37223882
Sustained changes in lipid profile and macrophage migration inhibitory factor levels after anti-tumour necrosis factor therapy in rheumatoid arthritisQ37245188
Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinibQ37257476
Tumour necrosis factor antagonists and the risk of cardiovascular disease in patients with rheumatoid arthritis: a systematic literature reviewQ37808889
Cardiovascular risk and the use of biologic agents in rheumatoid arthritisQ38260198
Cardiovascular comorbidity in rheumatic diseasesQ38568465
Incident myocardial infarction associated with major types of arthritis in the general population: a systematic review and meta-analysisQ38951238
Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic ArthritisQ38958215
Longterm Safety of Rituximab: Final Report of the Rheumatoid Arthritis Global Clinical Trial Program over 11 YearsQ40639756
Longterm Safety of Tocilizumab: Results from 3 Years of Followup Postmarketing Surveillance of 5573 Patients with Rheumatoid Arthritis in JapanQ40879218
Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid ArthritisQ40959053
Chronic inhibition of tumor necrosis factor-α with infliximab improves myocardial deformation in parallel with aortic elasticity in rheumatoid arthritisQ42474358
Effect of Long-Term TNF-α Inhibition with Infliximab on Left Ventricular Torsion in Patients with Rheumatoid Arthritis.Q42483149
Tocilizumab monotherapy reduces arterial stiffness as effectively as etanercept or adalimumab monotherapy in rheumatoid arthritis: an open-label randomized controlled trialQ42611547
Effects of infliximab treatment in terms of cardiovascular risk and insulin resistance in ankylosing spondylitis patientsQ43482103
Open-label tofacitinib and double-blind atorvastatin in rheumatoid arthritis patients: a randomised studyQ43686388
Tocilizumab inhibits structural joint damage and improves physical function in patients with rheumatoid arthritis and inadequate responses to methotrexate: LITHE study 2-year resultsQ43957207
Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trialQ44165611
The association between inflammatory markers, serum lipids and the risk of cardiovascular events in patients with rheumatoid arthritisQ44558171
Short term effects of infliximab on the lipid profile in patients with rheumatoid arthritisQ45251969
Tumour necrosis factor {alpha} blockade reduces circulating N-terminal pro-brain natriuretic peptide levels in patients with active rheumatoid arthritis: results from a prospective cohort study.Q45939167
Risk of incident cardiovascular events in patients with rheumatoid arthritis: a meta-analysis of observational studies.Q46003173
Cardiometabolic profile, clinical features, quality of life and treatment outcomes in patients with moderate-to-severe psoriasis and psoriatic arthritisQ46085062
Anti-inflammatory therapy with tumour necrosis factor alpha inhibitors improves high-density lipoprotein cholesterol antioxidative capacity in rheumatoid arthritis patientsQ46477622
Etanercept normalises left ventricular mass in patients with rheumatoid arthritis.Q46521163
Effects of repeated infliximab therapy on serum lipid profile in patients with refractory rheumatoid arthritisQ46714949
Induction of hyperadiponectinemia following long-term treatment of patients with rheumatoid arthritis with infliximab (IFX), an anti-TNF-alpha antibodyQ46757443
Impact of 24-month treatment with etanercept, adalimumab, or methotrexate on metabolic syndrome components in a cohort of 210 psoriatic arthritis patientsQ47743748
Sustained efficacy of certolizumab pegol added to methotrexate in the treatment of rheumatoid arthritis: 2-year results from the RAPID 1 trialQ49218023
Cardiovascular and other comorbidities in patients with psoriatic arthritis: a comparison with patients with psoriasis.Q51009674
Infliximab but not methotrexate induces extra-high levels of VLDL-triglyceride in patients with rheumatoid arthritis.Q51464070
Beneficial effect of 1-year etanercept treatment on the lipid profile in responding patients with rheumatoid arthritis: the ETRA study.Q51695204
The effects of golimumab on subclinical atherosclerosis and arterial stiffness in ankylosing spondylitis—a randomized, placebo-controlled pilot trial.Q53095551
Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis.Q53249650
Conversion towards an atherogenic lipid profile in rheumatoid arthritis patients during long‐term infliximab therapyQ57819586
Tofacitinib or Adalimumab versus Placebo in Rheumatoid ArthritisQ58912330
Infliximab is Associated with Improvement in Arterial Stiffness in Patients with Early Rheumatoid Arthritis -- A Randomized TrialQ59123639
Tofacitinib in Combination With Nonbiologic Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid ArthritisQ60061984
Newly Identified Antiatherosclerotic Activity of Methotrexate and Adalimumab: Complementary Effects on Lipoprotein Function and Macrophage Cholesterol MetabolismQ60241022
Etanercept improves inflammation-associated arterial stiffness in rheumatoid arthritisQ61830824
Modest but sustained increase of serum high density lipoprotein cholesterol levels in patients with inflammatory arthritides treated with infliximabQ79170004
Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: findings of a fifty-two-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group stQ79765442
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexateQ80201780
A placebo-controlled, randomized, double-blinded study evaluating the safety of etanercept in patients with rheumatoid arthritis and concomitant comorbid diseasesQ80241608
A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate aloneQ82066071
The platelet functions in patients with ankylosing spondylitis: anti-TNF-alpha therapy decreases the mean platelet volume and platelet massQ82404260
P275copyright licenseCreative Commons Attribution-NonCommercialQ6936496
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcardiovascular diseaseQ389735
rheumatismQ684924
pyrimidineQ47069735
pyrroleQ67954132
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)473-488
P577publication date2018-05-01
P1433published inDrug SafetyQ15724462
P1476titleThe Impact of Biologics and Tofacitinib on Cardiovascular Risk Factors and Outcomes in Patients with Rheumatic Disease: A Systematic Literature Review
P478volume41

Reverse relations

cites work (P2860)
Q60959818Targeting Inflammation to Prevent Cardiovascular Disease in Chronic Rheumatic Diseases: Myth or Reality?
Q61807469Therapeutic Targeting of the Proinflammatory IL-6-JAK/STAT Signalling Pathways Responsible for Vascular Restenosis in Type 2 Diabetes Mellitus

Search more.