The landscape of somatic mutations in Indonesian cervical cancer is predominated by the PI3K pathway

scientific article

The landscape of somatic mutations in Indonesian cervical cancer is predominated by the PI3K pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YGYNO.2017.10.009
P698PubMed publication ID29113722

P50authorEkaterina S. JordanovaQ41602380
Gatot PurwotoQ79160403
P2093author name stringAlexander A W Peters
Gert J Fleuren
Vivian M Spaans
Marjolijn D Trietsch
Natalja Ter Haar
I Nyoman Bayu Mahendra
Michelle Osse
P2860cites workThe PI3K pathway as drug target in human cancerQ24632283
Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label studyQ27276774
Systemic targeted therapy for her2-positive early female breast cancer: a systematic review of the evidence for the 2014 Cancer Care Ontario systemic therapy guidelineQ28260063
Prevalence of single and multiple HPV types in cervical carcinomas in Jakarta, IndonesiaQ33200323
Prevalence of human papillomavirus in Indonesia: a population-based study in three regionsQ33349978
Epidemiology and prevention of cervical cancer in Indonesia, Malaysia, the Philippines, Thailand and VietnamQ33378843
A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodesQ33541323
Landscape of genomic alterations in cervical carcinomasQ34169464
Integrative genomic approaches in cervical cancer: implications for molecular pathogenesisQ34569934
Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancersQ35132338
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Precise Classification of Cervical Carcinomas Combined with Somatic Mutation Profiling Contributes to Predicting Disease Outcome.Q35702897
Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancersQ35741587
Single and multiple high-risk and low-risk Human Papillomavirus association with cervical lesions of 11,224 women in JakartaQ36165724
Impact of human papilloma virus vaccination on adolescent knowledge, perception of sexual risk and need for safer sexual behaviors in Bali, IndonesiaQ36168769
Somatic Variations in Cervical Cancers in Indian PatientsQ36187364
Genetic profiles of cervical tumors by high-throughput sequencing for personalized medical care.Q36201454
Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA PathwayQ36342871
Epigenetic alterations in preneoplastic and neoplastic lesions of the cervixQ36412445
PIK3CA mutation H1047R is associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trialsQ36510935
Somatic mutation in PIK3CA is a late event in cervical carcinogenesisQ37082560
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Oncogenic mutations in cervical cancer: genomic differences between adenocarcinomas and squamous cell carcinomas of the cervixQ37678092
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Treatment of NRAS-mutant melanoma.Q38386344
Emerging strategies for targeting PI3K in gynecologic cancerQ38598081
Management of patients with recurrent/advanced cervical cancer beyond first line platinum regimens: Where do we stand? A literature review.Q39033368
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppressionQ39904718
Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese womenQ41519401
Activated PI3K/Akt/COX-2 pathway induces resistance to radiation in human cervical cancer HeLa cellsQ43005361
Human papillomavirus types in 115,789 HPV-positive women: a meta-analysis from cervical infection to cancerQ43596600
Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervixQ43705732
Human papillomavirus type distribution in 30,848 invasive cervical cancers worldwide: Variation by geographical region, histological type and year of publicationQ47860026
Genetic alterations of PIK3CA and tumor response in patients with locally advanced cervical squamous cell carcinoma treated with cisplatin-based concurrent chemoradiotherapy.Q53291150
The Path to Cancer --Three Strikes and You're OutQ86680630
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectIndonesiaQ252
P304page(s)189-196
P577publication date2017-11-04
P1433published inGynecologic OncologyQ5625182
P1476titleThe landscape of somatic mutations in Indonesian cervical cancer is predominated by the PI3K pathway
P478volume148

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cites work (P2860)
Q61807141MGL Ligand Expression Is Correlated to Lower Survival and Distant Metastasis in Cervical Squamous Cell and Adenosquamous Carcinoma
Q55209571Molecular profiles and tumor mutational burden analysis in Chinese patients with gynecologic cancers.
Q95728096Pretreatment Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) as a Predictive Value of Hematological Markers in Cervical Cancer

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