Effects of central FGF21 infusion on the hypothalamus-pituitary-thyroid axis and energy metabolism in rats

scientific article published on 7 February 2018

Effects of central FGF21 infusion on the hypothalamus-pituitary-thyroid axis and energy metabolism in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12576-018-0595-7
P698PubMed publication ID29417398

P2093author name stringMehmet Demir
Yilmaz Cigremis
Suat Tekin
Suleyman Sandal
Umit Yilmaz
P2860cites workPotential roles of fibroblast growth factor 21 in the brainQ38688679
Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1.Q40958865
The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissueQ41912342
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese miceQ43224118
Fibroblast growth factor-21 is expressed in neonatal and pheochromocytoma-induced adult human brown adipose tissueQ43584960
Increased responses to the actions of fibroblast growth factor 21 on energy balance and body weight in a seasonal model of adiposityQ43589056
Plasma FGF21 levels are increased in patients with hypothyroidism independently of lipid profileQ46309699
The uncoupling proteins, a reviewQ47690531
Effects of central fibroblast growth factor 21 (FGF21) in energy balance.Q47826803
Role of macrophages in depot-dependent browning of white adipose tissue.Q47844391
FGF21 maintains glucose homeostasis by mediating the cross talk between liver and brain during prolonged fastingQ48659709
Relationship between FGF21 and UCP1 levels under time-restricted feeding and high-fat diet.Q51046770
Thyroid hormone receptor regulates most genes independently of fibroblast growth factor 21 in liver.Q51310990
Upregulation of rat liver PPARα-FGF21 signaling by a docosahexaenoic acid and thyroid hormone combined protocol.Q51726693
Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein.Q52163868
The effects of intracerebroventricular infusion of apelin-13 on reproductive function in male rats.Q53437928
Pharmacologic Effects of FGF21 Are Independent of the "Browning" of White Adipose Tissue.Q53514538
Fibroblast growth factor-21 restores insulin sensitivity but induces aberrant bone microstructure in obese insulin-resistant rats.Q53791866
Recombinant murine fibroblast growth factor 21 ameliorates obesity-related inflammation in monosodium glutamate-induced obesity ratsQ85758504
Letter to the Editor: Potential Role for FGF21 as a Mediator of Thyroid Hormone Effects on Metabolic RegulationQ86864913
FGF-21 as a novel metabolic regulatorQ24523933
Adipose tissues and thyroid hormonesQ27025566
Physiological and molecular basis of thyroid hormone actionQ28203934
FGF21 contributes to neuroendocrine control of female reproductionQ30414627
Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat.Q33762194
Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent mannerQ33825136
Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese ratsQ33930333
BMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant productionQ34101070
FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss.Q34315567
The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.Q34577053
Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21.Q34778879
Fibroblast growth factor 21 corrects obesity in miceQ34805555
Thyroid hormone signaling in energy homeostasis and energy metabolismQ35671563
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesisQ35755169
Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male MiceQ35763646
Evolution of the Fgf and Fgfr gene familiesQ35913683
Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans.Q36196859
FGF21 and the late adaptive response to starvation in humansQ36335835
Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: relationship between FGF21 levels, lipolysis, and cold-induced thermogenesis.Q36508902
Detection of thermogenesis in rodents in response to anti-obesity drugs and genetic modification.Q36746883
An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in miceQ36886578
The FGF family: biology, pathophysiology and therapyQ36933339
FGF21 regulates metabolism and circadian behavior by acting on the nervous systemQ37161082
Fibroblast growth factor 21: a novel metabolic regulator with potential therapeutic properties in obesity/type 2 diabetes mellitus.Q37426678
Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivoQ37709208
Fibroblast growth factor 21, assisted by elevated glucose, activates paraventricular nucleus NUCB2/Nesfatin-1 neurons to produce satiety under fed statesQ37736500
Thyroid hormone action in metabolic regulationQ37879999
Role of the hypothalamus in the neuroendocrine regulation of body weight and composition during energy deficitQ37954380
FGF21: The center of a transcriptional nexus in metabolic regulationQ38010226
Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiologyQ38077471
P577publication date2018-02-07
P1433published inJournal of Physiological SciencesQ15767208
P1476titleEffects of central FGF21 infusion on the hypothalamus-pituitary-thyroid axis and energy metabolism in rats

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cites work (P2860)
Q93216608FGF21 Mimics a Fasting-Induced Metabolic State and Increases Appetite in Zebrafish
Q98238156The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic

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