Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth

scientific article published on 4 October 2016

Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.DEVCEL.2016.09.005
P932PMC publication ID5121000
P698PubMed publication ID27720608

P50authorZhiqiang LinQ56998519
P2093author name stringJin Zhang
Amy Li
Feng Liang
Qing Ma
Aibin He
Pingzhu Zhou
William T Pu
Yuan Cao
Vassilios J Bezzerides
Yuxuan Guo
Sean M Stevens
Cristobal Dos Remedios
Qimin Quan
Sylvia Zohrabian
Haidong Guo
Nathan VanDusen
Pim R van Gorp
P2860cites workYap1 acts downstream of α-catenin to control epidermal proliferationQ24294904
The Hippo pathway regulates Wnt/beta-catenin signalingQ24307606
A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancerQ24337135
L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and LQ24531160
The Hippo Signaling Pathway in Development and CancerQ24603986
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic miceQ24670468
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAPQ28266862
The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repressionQ28291847
The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expressionQ28504813
Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart sizeQ28507019
YAP1 increases organ size and expands undifferentiated progenitor cellsQ28592519
Role of YAP/TAZ in mechanotransductionQ29615411
Direct observation of individual endogenous protein complexes in situ by proximity ligationQ29616032
p300/CBP proteins: HATs for transcriptional bridges and scaffoldsQ29617981
Elucidation of a universal size-control mechanism in Drosophila and mammalsQ29618935
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cellsQ29619410
Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distributionQ30431585
MCAT elements and the TEF-1 family of transcription factors in muscle development and diseaseQ30444840
Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion.Q33846400
Strategies for cardiac regeneration and repairQ34795299
Alpha-catenins control cardiomyocyte proliferation by regulating Yap activityQ34807247
PRC2 directly methylates GATA4 and represses its transcriptional activityQ35674575
YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophyQ35787211
Statistical analysis of the genomic distribution and correlation of regulatory elements in the ENCODE regionsQ35840712
Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failureQ35921523
Yes-associated protein regulates the hepatic response after bile duct ligationQ36200492
YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic EnhancersQ36219267
Myocyte proliferation in end-stage cardiac failure in humansQ36221185
Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart sizeQ36231054
Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injuryQ36596197
Hippo pathway effector Yap promotes cardiac regenerationQ37117699
Hippo signaling impedes adult heart regeneration.Q37323625
Forecasting the impact of heart failure in the United States: a policy statement from the American Heart AssociationQ37538031
Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growthQ38844916
Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI modelQ41994688
A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agentsQ42211262
Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes.Q42461541
Releasing YAP from an α-catenin trap increases cardiomyocyte proliferation.Q43090219
Cardiomyocyte cell cycle control and growth estimation in vivo--an analysis based on cardiomyocyte nucleiQ43195307
Control of the hippo pathway by Set7-dependent methylation of Yap.Q46240754
Structures and activities of protease inhibitors of microbial originQ68237037
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectYes-associated protein 1Q21498262
E1A binding protein p300Q21981065
TEA domain family member 1Q21990678
Vestigial like family member 4Q21990685
P1104number of pages14
P304page(s)466-479
P577publication date2016-10-04
P1433published inDevelopmental CellQ1524277
P1476titleAcetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth
P478volume39

Reverse relations

cites work (P2860)
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Q92154541Cell-Based Mechanosensation, Epigenetics, and Non-Coding RNAs in Progression of Cardiac Fibrosis
Q49545706Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence
Q38952768Expression Profiling of Clinical Specimens Supports the Existence of Neural Progenitor-Like Stem Cells in Basal Breast Cancers
Q90735622Hippo Deficiency Leads to Cardiac Dysfunction Accompanied by Cardiomyocyte Dedifferentiation During Pressure Overload
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Q41013371MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy.
Q59335899Mediated nuclear import and export of TAZ and the underlying molecular requirements
Q98466300Multiple Roles of Vestigial-Like Family Members in Tumor Development
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Q55447872Serotonin and YAP/VGLL4 Balance Correlated with Progression and Poor Prognosis of Hepatocellular Carcinoma.
Q42162747Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy.
Q64097525Tead1 is required for perinatal cardiomyocyte proliferation
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Q91675882Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c
Q92023843aYAP modRNA reduces cardiac inflammation and hypertrophy in a murine ischemia-reperfusion model

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