Can we deliver randomized trials of focal therapy in prostate cancer?

scientific article published on 22 April 2014

Can we deliver randomized trials of focal therapy in prostate cancer? is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1035395995
P356DOI10.1038/NRCLINONC.2014.44
P8608Fatcat IDrelease_2xyxdezuljexrdlxfsafj2yidm
P698PubMed publication ID24751803
P5875ResearchGate publication ID261769990

P50authorAndrew VickersQ20055453
Matthew R SydesQ44571830
Clare ReltonQ48342161
Tom LeslieQ55644865
Mark EmbertonQ63968187
P2093author name stringTimothy Wilt
Chris Parker
Hashim U Ahmed
Richard Stephens
Jan van der Meulen
Richard Kaplan
Rakesh Heer
David Bottomley
Viktor Berge
William Cross
Lindsay Turnbull
Prostate Cancer RCT Consensus Group
P2860cites workProstate cancer diagnosis and treatment after the introduction of prostate-specific antigen screening: 1986-2005Q24656098
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Image guided photothermal focal therapy for localized prostate cancer: phase I trialQ33493721
???Q56773413
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Few patients with prostate cancer are willing to be randomised to treatmentQ33796146
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The role of focal therapy in the management of localised prostate cancer: a systematic reviewQ34266167
The changing face of low-risk prostate cancer: trends in clinical presentation and primary managementQ34380870
Do low-grade and low-volume prostate cancers bear the hallmarks of malignancy?Q34463984
Quality improvement report: Improving design and conduct of randomised trials by embedding them in qualitative research: ProtecT (prostate testing for cancer and treatment) study. Commentary: presenting unbiased information to patients can be difficQ34938393
Feasibility study of a clinically-integrated randomized trial of modifications to radical prostatectomyQ35819260
Radical prostatectomy versus observation for localized prostate cancerQ36194308
Developing core outcome sets for clinical trials: issues to considerQ36320178
Targeted biopsy in the detection of prostate cancer using an office based magnetic resonance ultrasound fusion deviceQ36579232
Transatlantic Consensus Group on active surveillance and focal therapy for prostate cancerQ36928846
Will focal therapy become a standard of care for men with localized prostate cancer?Q36983662
Low suspicion lesions on multiparametric magnetic resonance imaging predict for the absence of high-risk prostate cancerQ37254919
Geometric evaluation of systematic transrectal ultrasound guided prostate biopsyQ37421874
New directions for patient-centred care in scleroderma: the Scleroderma Patient-centred Intervention Network (SPIN).Q37586400
Prostate cancer screening and the management of clinically localized diseaseQ37609671
Pathology of prostate cancer and focal therapy ('male lumpectomy').Q37665791
Tumor focality in prostate cancer: implications for focal therapyQ37813395
A biomedical engineering approach to mitigate the errors of prostate biopsyQ37981828
Image-guided prostate biopsy using magnetic resonance imaging-derived targets: a systematic reviewQ38022388
MR imaging-guided focal laser ablation for prostate cancer: phase I trialQ38084585
Multiparametric MR imaging for detection of clinically significant prostate cancer: a validation cohort study with transperineal template prostate mapping as the reference standardQ38097009
Prostate cancer diagnosis: multiparametric MR-targeted biopsy with cognitive and transrectal US-MR fusion guidance versus systematic biopsy--prospective multicenter studyQ38098361
MRI-targeted prostate biopsy: a review of technique and resultsQ38141793
SABRE 1 (Surgery Against Brachytherapy - a Randomised Evaluation): feasibility randomised controlled trial (RCT) of brachytherapy vs radical prostatectomy in low-intermediate risk clinically localised prostate cancer.Q39390819
The PICTURE study -- prostate imaging (multi-parametric MRI and Prostate HistoScanning™) compared to transperineal ultrasound guided biopsy for significant prostate cancer risk evaluationQ39464626
Performance of transperineal template-guided mapping biopsy in detecting prostate cancer in the initial and repeat biopsy settingQ39477975
Quantitative tissue analyses of prostate cancer foci in an unselected cystoprostatectomy seriesQ39672788
Southwest Oncology Group strategies in prostatic carcinomaQ40527704
Randomised consent designs in cancer clinical trialsQ40945544
Clinical-pathologic correlation between transperineal mapping biopsies of the prostate and three-dimensional reconstruction of prostatectomy specimensQ43196725
A prospective, blinded comparison of magnetic resonance (MR) imaging-ultrasound fusion and visual estimation in the performance of MR-targeted prostate biopsy: the PROFUS trialQ43493324
A negative confirmatory biopsy among men on active surveillance for prostate cancer does not protect them from histologic grade progressionQ43861193
Initial management of low-risk localized prostate cancer in the UK: analysis of the British Association of Urological Surgeons Cancer RegistryQ44321478
Interpreting composite outcomes in trials.Q44590878
Complications and quality of life after template-assisted transperineal prostate biopsy in patients eligible for focal therapy.Q45905031
Focal salvage therapy for localized prostate cancer recurrence after external beam radiotherapy: a pilot study.Q45937049
Drug and device development for localized prostate cancer: report of a Food and Drug Administration/American Urological Association public workshopQ46437041
Focal cryotherapy for clinically unilateral, low-intermediate risk prostate cancer in 73 men with a median follow-up of 3.7 years.Q46663012
Comparison of health-related quality of life 5 years after SPIRIT: Surgical Prostatectomy Versus Interstitial Radiation Intervention TrialQ48730138
A randomized trial of external beam radiotherapy versus cryoablation in patients with localized prostate cancer: quality of life outcomesQ49074752
Focal therapy for localized prostate cancer: a phase I/II trialQ50246484
Transperineal magnetic resonance image targeted prostate biopsy versus transperineal template prostate biopsy in the detection of clinically significant prostate cancer.Q50904451
Incidence of bone metastases in breast cancer patients in the United Kingdom: results of a multi-database linkage study using the general practice research database.Q51255912
Rethinking pragmatic randomised controlled trials: introducing the "cohort multiple randomised controlled trial" designQ56780191
Impact of a multi-disciplinary patient education session on accrual to a difficult clinical trial: the Toronto experience with the surgical prostatectomy versus interstitial radiation intervention trialQ56786889
Radical prostatectomy versus watchful waiting in early prostate cancerQ57137210
Early closure of a randomized controlled trial of three treatment approaches to early localised prostate cancer: the MRC PR06 trialQ60716163
Dynamic Contrast-enhanced–magnetic Resonance Imaging Evaluation of Intraprostatic Prostate Cancer: Correlation with Radical Prostatectomy SpecimensQ63966229
Randomized trial comparing cryoablation and external beam radiotherapy for T2C-T3B prostate cancerQ80501175
Focal cryotherapy for localized prostate cancer: a report from the national Cryo On-Line Database (COLD) RegistryQ82246523
Driving up the quality and relevance of research through the use of agreed core outcomesQ83374039
Accuracy of primary systematic template guided transperineal biopsy of the prostate for locating prostate cancer: a comparison with radical prostatectomy specimensQ83875358
Prostate biopsy in selecting candidates for hemiablative focal therapyQ84008631
Characterizing clinically significant prostate cancer using template prostate mapping biopsyQ84378694
Prostate cancer--uncertainty and a way forwardQ84585046
The index lesion and the origin of prostate cancerQ84761775
A randomized trial of external beam radiotherapy versus cryoablation in patients with localized prostate cancerQ84950601
Diagnostic tests in urology: magnetic resonance imaging (MRI) for the staging of prostate cancerQ85898760
P2507corrigendum / erratumCorrigendum: Can we deliver randomized trials of focal therapy in prostate cancer?Q50141300
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectprostate cancerQ181257
P304page(s)482-491
P577publication date2014-04-22
P1433published inNature Reviews Clinical OncologyQ641640
P1476titleCan we deliver randomized trials of focal therapy in prostate cancer?
P478volume11

Reverse relations

cites work (P2860)
Q58794132A Multicentre Study of 5-year Outcomes Following Focal Therapy in Treating Clinically Significant Nonmetastatic Prostate Cancer
Q30367832Contrast-enhanced transrectal ultrasound for prediction of prostate cancer aggressiveness: The role of normal peripheral zone time-intensity curves
Q50141300Corrigendum: Can we deliver randomized trials of focal therapy in prostate cancer?
Q38436625Current trends and new frontiers in focal therapy for localized prostate cancer
Q36049690Final Results of a Phase I/II Multicenter Trial of WST11 Vascular Targeted Photodynamic Therapy for Hemi-Ablation of the Prostate in Men with Unilateral Low Risk Prostate Cancer Performed in the United States
Q50138465Focal Ablation of Early-Stage Prostate Cancer: Candidate Selection, Treatment Guidance, and Assessment of Outcome
Q40308955Focal salvage high-intensity focused ultrasound in radiorecurrent prostate cancer
Q30240753Focal therapy as primary treatment for localized prostate cancer: definition, needs and future
Q50241890Focal therapy for prostate cancer: German version
Q41689116Focal therapy for prostate cancer: the technical challenges.
Q57297211Focal therapy in localised prostate cancer: Real-world urological perspective explored in a cross-sectional European survey
Q35540067Focal therapy: patients, interventions, and outcomes--a report from a consensus meeting
Q89059998Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer
Q36231929Padeliporfin vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer (CLIN1001 PCM301): an open-label, phase 3, randomised controlled trial
Q88209404Pair-matched patient-reported quality of life and early oncological control following focal irreversible electroporation versus robot-assisted radical prostatectomy
Q48302699Partial Gland Ablation for Prostate Cancer: Report of a Food and Drug Administration, American Urological Association, and Society of Urologic Oncology Public Workshop
Q89845717Prospective evaluation of fexapotide triflutate injection treatment of Grade Group 1 prostate cancer: 4-year results
Q85208632Re: Jarow et al.: Drug and device development for localized prostate cancer: report of a Food and Drug Administration/American Urological Association public workshop (Urology 2014;83:975-979)
Q40875442Role of active surveillance and focal therapy in low- and intermediate-risk prostate cancers
Q38668993The challenging landscape of medical device approval in localized prostate cancer
Q57112886Which technology to select for primary focal treatment of prostate cancer?-European Section of Urotechnology (ESUT) position statement

Q50141300Corrigendum: Can we deliver randomized trials of focal therapy in prostate cancer?main subjectP921

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