HSP90 [cytosol]

instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-1221657)

Wikidata entity: Q50251177



P2888 exact match Url None ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q21108142 (Heat shock protein 90 alpha family class A member 1) Heat shock protein 90 alpha family class A member 1
P31 instance of ... Q420927 (protein complex) protein complex
P361 part of ... Q50251174 (HSP90:HSP90 [cytosol]) HSP90:HSP90 [cytosol]
P361 part of ... Q50255455 (Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]) Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255456 (Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]) Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255458 (EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]) EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255459 (EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]) EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255469 (EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]) EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255471 (EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]) EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255475 (Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]) Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255476 (Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]) Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255491 (HSP90:Benzoquinoid ansamycins [cytosol]) HSP90:Benzoquinoid ansamycins [cytosol]
P361 part of ... Q50255506 (EGFRvIII mutant:HSP90:CDC37 [plasma membrane]) EGFRvIII mutant:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50255510 (Phospho-EGFRvIIImut:HSP90:CDC37 [plasma membrane]) Phospho-EGFRvIIImut:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50271847 (ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50271915 (Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane]) Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane]
P361 part of ... Q50271916 (Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]) Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q50288592 (Binding of ligand-responsive EGFR mutants to chaperoning proteins HSP90 and CDC37) Binding of ligand-responsive EGFR mutants to chaperoning proteins HSP90 and CDC37
P361 part of ... Q50288621 (HSP90 is inactivated by binding to benzaquinoid ansamycins) HSP90 is inactivated by binding to benzaquinoid ansamycins
P361 part of ... Q50288625 (EGFRvIII mutant binds chaperone proteins HSP90 and CDC37.) EGFRvIII mutant binds chaperone proteins HSP90 and CDC37.
P361 part of ... Q50297986 (ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4) ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4
P361 part of ... Q99587980 (HSP90:HSF1 [cytosol]) HSP90:HSF1 [cytosol]
P361 part of ... Q100146881 (ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146884 (ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146889 (ERBB2 KD mutants:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146929 (ERBB2 KD mutants:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146932 (ERBB2 KD mutants (trastuzumab sensitive):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants (trastuzumab sensitive):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146950 (ERBB2 KD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146952 (ERBB2 KD mutants (trastuzumab sensitive):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants (trastuzumab sensitive):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146954 (ERBB2 KD mutants (trastuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants (trastuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146956 (ERBB2 KD mutants (lapatinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants (lapatinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146958 (ERBB2 KD mutants (neratinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants (neratinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146960 (ERBB2 KD mutants (osimertinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants (osimertinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146961 (ERBB2 T798M:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 T798M:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146962 (ERBB2 T733I:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 T733I:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146963 (ERBB2 T862A:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 T862A:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146965 (ERBB2 KD mutants (AEE788 resistant):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 KD mutants (AEE788 resistant):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146967 (ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100146983 (ERBB2 TMD/JMD mutants:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 TMD/JMD mutants:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100147000 (ERBB2 TMD/JMD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 TMD/JMD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100147005 (ERBB2 TMD/JMD mutants (TKI sensitive):TKI:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 TMD/JMD mutants (TKI sensitive):TKI:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100147007 (ERBB2 TMD/JMD mutants (trastuzumab):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 TMD/JMD mutants (trastuzumab):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100147009 (ERBB2 TMD/JMD mutants (trastuzumab):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 TMD/JMD mutants (trastuzumab):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100147010 (ERBB2 R678Q:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 R678Q:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100147012 (ERBB2 R678Q:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 R678Q:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100147014 (ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100149155 (ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane]) ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane]
P361 part of ... Q100152330 (ERBB2 homodimerization) ERBB2 homodimerization
P361 part of ... Q100152343 (ERBB2 KD mutants heterodimerize) ERBB2 KD mutants heterodimerize
P361 part of ... Q100152383 (ERBB2 ECD mutants heterodimerize with EGFR) ERBB2 ECD mutants heterodimerize with EGFR
P361 part of ... Q100152407 (ERBB2 TMD/JMD mutants hetrodimerize) ERBB2 TMD/JMD mutants hetrodimerize
P361 part of ... Q101208674 (RIPK3:HSP90:CDC37 [cytosol]) RIPK3:HSP90:CDC37 [cytosol]
P361 part of ... Q101208675 (MLKL:HSP90:CDC37 [cytosol]) MLKL:HSP90:CDC37 [cytosol]
P361 part of ... Q101226955 (RIPK3 binds HSP90:CDC37) RIPK3 binds HSP90:CDC37
P361 part of ... Q101226965 (MLKL binds HSP90:CDC37) MLKL binds HSP90:CDC37

External Ids
P3937Reactome IDR-HSA-1221657

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log id: 5305969