ERAD complex [endoplasmic reticulum membrane]

instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-8866531)

Wikidata entity: Q50256276



P2888 exact match Url Reactome | ERAD complex [endoplasmic reticulum membrane] ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q21122058 (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase) SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
P527 has part(s) ... Q50256141 (OS9/ERLEC1 [endoplasmic reticulum quality control compartment]) OS9/ERLEC1 [endoplasmic reticulum quality control compartment]
P527 has part(s) ... Q50256145 (VCP hexamer [cytosol]) VCP hexamer [cytosol]
P527 has part(s) ... Q50256277 (DERL oligomer [endoplasmic reticulum membrane]) DERL oligomer [endoplasmic reticulum membrane]
P527 has part(s) ... Q50256279 (RNF5,RNF185 [endoplasmic reticulum membrane]) RNF5,RNF185 [endoplasmic reticulum membrane]
P527 has part(s) ... Q100147266 (ERLIN1:ERLIN2 [endoplasmic reticulum membrane]) ERLIN1:ERLIN2 [endoplasmic reticulum membrane]
P31 instance of ... Q420927 (protein complex) protein complex
P361 part of ... Q50256281 (CFTR F508del:ERAD complex [endoplasmic reticulum membrane]) CFTR F508del:ERAD complex [endoplasmic reticulum membrane]
P361 part of ... Q50256282 (ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane]) ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane]
P361 part of ... Q50274403 (misfolded CFTR:ERAD complex [endoplasmic reticulum membrane]) misfolded CFTR:ERAD complex [endoplasmic reticulum membrane]
P361 part of ... Q50274404 (Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane]) Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane]
P361 part of ... Q50288960 (CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation) CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation
P361 part of ... Q50288962 (VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol) VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol
P361 part of ... Q50299398 (CFTR binds components of the ERAD machinery for ubiquitination and degradation) CFTR binds components of the ERAD machinery for ubiquitination and degradation
P361 part of ... Q50299400 (VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol) VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol

External Ids
P3937Reactome IDR-HSA-8866531

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