Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2.

scientific article published on 14 February 2018

Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/S41598-018-21189-0
P932PMC publication ID5813005
P698PubMed publication ID29445227

P2093author name stringNoriyuki Murai
Senya Matsufuji
Yasuko Murakami
Ayasa Tajima
P2860cites workAntizyme1 mediates AURKAIP1-dependent degradation of Aurora-A.Q51798018
Polyamine regulating protein antizyme binds to ATP citrate lyase to accelerate acetyl-CoA production in cancer cells.Q52883151
Mammalian MYC Proteins and CancerQ59072385
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7Q24337643
The ornithine decarboxylase gene is a transcriptional target of c-MycQ24561758
Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious useQ26970809
OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouseQ27348649
Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizymeQ28117992
Structural elements of antizymes 1 and 2 are required for proteasomal degradation of ornithine decarboxylaseQ28204996
A second mammalian antizyme: conservation of programmed ribosomal frameshiftingQ28286114
Mechanisms of c-myc degradation by nickel compounds and hypoxiaQ33521691
The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathwayQ33740186
The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplificationQ33761692
Regulation of cellular polyamines by antizymeQ34193267
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradationQ34835596
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.Q35204486
Reflecting on 25 years with MYC.Q37333643
Mammalian polyamine metabolism and functionQ37365983
MYC as a regulator of ribosome biogenesis and protein synthesisQ37718002
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.Q40456137
Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repressionQ40531220
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cellsQ40572608
Involvement of antizyme in stabilization of ornithine decarboxylase caused by inhibitors of polyamine synthesisQ41260604
Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitinationQ41589996
Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcriptionQ42254875
Distinct domains of antizyme required for binding and proteolysis of ornithine decarboxylaseQ42267971
Identification of nuclear export signals in antizyme-1.Q42797767
Subcellular localization and phosphorylation of antizyme 2.Q42834221
Downregulation of c-MYC protein levels contributes to cancer cell survival under dual deficiency of oxygen and glucoseQ42845702
Accumulation of c-Myc and proteasomes at the nucleoli of cells containing elevated c-Myc protein levelsQ44383055
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell sizeQ45118851
Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylaseQ46245197
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)3005
P577publication date2018-02-14
P1433published inScientific ReportsQ2261792
P1476titleNovel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2.
P478volume8

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cites work (P2860)
Q57291214Antizyme Inhibitors in Polyamine Metabolism and Beyond: Physiopathological Implications
Q58596589Polyamine synthesis as a target of MYC oncogenes
Q57792063The Antizyme family for regulating polyamines
Q58701919Triterpene Acid (---Coumaroyltormentic Acid) Isolated From Aronia Extracts Inhibits Breast Cancer Stem Cell Formation through Downregulation of c-Myc Protein

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