Calcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: mechanisms of action.

scientific article published on 11 November 2013

Calcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: mechanisms of action. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/CVR/CVT249
P698PubMed publication ID24217682

P50authorTilman B DruekeQ47097110
P2093author name stringZiad A Massy
Romuald Mentaverri
Sebastien Dupont
Aurélien Mary
Cédric Boudot
Michel Brazier
Saïd Kamel
Lucie Hénaut
Irene Lopez-Fernandez
P2860cites workArterial calcification in chronic kidney disease: key roles for calcium and phosphateQ26827655
A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremiaQ28568245
Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogramming toward osteochondrogenesisQ33952717
Calcimimetic agents: review and perspectivesQ35129894
Effects of calcimimetics on extraskeletal calcifications in chronic kidney disease.Q37335068
Rescue of calcium-sensing receptor mutants by allosteric modulators reveals a conformational checkpoint in receptor biogenesisQ40173956
High affinity interaction with filamin A protects against calcium-sensing receptor degradation.Q40469635
The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibersQ41141776
Rapidly forming apatitic mineral in an osteoblastic cell line (UMR 106-01 BSP).Q41349301
Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers.Q43819702
Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteinsQ43889562
Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cellsQ44173368
Cartilaginous metaplasia in calcified diabetic peripheral vascular disease: Morphologic evidence of enchondral ossificationQ44431335
Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cellsQ45002024
The calcimimetic R-568 retards uremia-enhanced vascular calcification and atherosclerosis in apolipoprotein E deficient (apoE-/-) mice.Q46177693
Vascular calcification in chronic kidney diseaseQ46282253
Cinacalcet suppresses calcification of the aorta and heart in uremic ratsQ46350266
Effects of the calcimimetic cinacalcet HCl on cardiovascular disease, fracture, and health-related quality of life in secondary hyperparathyroidismQ46704863
Effect of oral calcium carbonate on aortic calcification in apolipoprotein E-deficient (apoE-/-) mice with chronic renal failure.Q46918498
Extracellular calcium sensing in rat aortic vascular smooth muscle cellsQ50091818
Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidismQ50112353
P433issue2
P304page(s)256-265
P577publication date2013-11-11
P1433published inCardiovascular ResearchQ4642329
P1476titleCalcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: mechanisms of action.
P478volume101

Reverse relations

cites work (P2860)
Q63707053Activation of the calcium-sensing receptor in human valvular interstitial cells promotes calcification
Q36122043Arterial Expression of the Calcium-Sensing Receptor Is Maintained by Physiological Pulsation and Protects against Calcification
Q37339940Associations of the calcium-sensing receptor gene CASR rs7652589 SNP with nephrolithiasis and secondary hyperparathyroidism in haemodialysis patients.
Q58229695Calcimimetic R-568 vasodilatory effect on mesenteric vascular beds from normotensive (WKY) and spontaneously hypertensive (SHR) rats. Potential involvement of vascular smooth muscle cells (vSMCs)
Q33918759Calcium Overload Accelerates Phosphate-Induced Vascular Calcification Via Pit-1, but not the Calcium-Sensing Receptor
Q28079054Calcium-Sensing Receptor Gene: Regulation of Expression
Q34472989Calcium-sensing receptor-mediated osteogenic and early-stage neurogenic differentiation in umbilical cord matrix mesenchymal stem cells from a large animal model
Q38565049Cinacalcet and Clinical Outcomes in Dialysis
Q85954935Comment on Bristow et al.: Dietary calcium: adverse or beneficial effects of supplements?
Q39103301Diseases associated with calcium-sensing receptor
Q42634602Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis
Q38473932Magnesium and cardiovascular complications of chronic kidney disease
Q50074589Magnesium supplementation: A consideration in dialysis patients
Q64114217Magnesium: A Magic Bullet for Cardiovascular Disease in Chronic Kidney Disease?
Q28087423Molecular Mechanisms of Vascular Calcification in Chronic Kidney Disease: The Link between Bone and the Vasculature
Q64231837NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs
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Q47264996Role of calcium-sensing receptor in regulating spontaneous activation of post-ovulatory aging rat oocytes†.
Q64241686Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia
Q40640099TWEAK favors phosphate-induced calcification of vascular smooth muscle cells through canonical and non-canonical activation of NFκB.
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