The high-osmolarity glycerol- and cell wall integrity-MAP kinase pathways of Saccharomyces cerevisiae are involved in adaptation to the action of killer toxin HM-1.

scientific article published on 15 October 2012

The high-osmolarity glycerol- and cell wall integrity-MAP kinase pathways of Saccharomyces cerevisiae are involved in adaptation to the action of killer toxin HM-1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/YEA.2927
P698PubMed publication ID23065846
P5875ResearchGate publication ID232248146

P2093author name stringYasuhiro Furuichi
Tadazumi Komiyama
Masahiko Miyamoto
P2860cites workEscape of Candida from caspofungin inhibition at concentrations above the MIC (paradoxical effect) accomplished by increased cell wall chitin; evidence for beta-1,6-glucan synthesis inhibition by caspofunginQ24674839
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDaQ27861105
The yeast aquaglyceroporin Fps1p is a bidirectional arsenite channel.Q27929750
Hog1 mitogen-activated protein kinase phosphorylation targets the yeast Fps1 aquaglyceroporin for endocytosis, thereby rendering cells resistant to acetic acidQ27930760
The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stressQ43069140
The osmotic integrity of the yeast cell requires a functional PKC1 gene productQ43116205
The high osmotic response and cell wall integrity pathways cooperate to regulate transcriptional responses to zymolyase-induced cell wall stress in Saccharomyces cerevisiaeQ43147138
Transcription factor Efg1 contributes to the tolerance of Candida albicans biofilms against antifungal agents in vitro and in vivoQ43861324
The protein kinase C pathway is required for viability in quiescence in Saccharomyces cerevisiaeQ43950172
When the stress of your environment makes you go HOG wildQ45165247
Presence of the Fps1p aquaglyceroporin channel is essential for Hog1p activation, but suppresses Slt2(Mpk1)p activation, with acetic acid stress of yeast.Q45927541
Studies of the paradoxical effect of caspofungin at high drug concentrationsQ46377599
Monoclonal antibodies and sandwich ELISA for quantitation of HM-1 killer toxinQ47632313
Isolation and nucleotide sequences of the genes encoding killer toxins from Hansenula mrakii and H. saturnusQ48087027
Investigating the caffeine effects in the yeast Saccharomyces cerevisiae brings new insights into the connection between TOR, PKC and Ras/cAMP signalling pathways.Q50724092
Involvement of cell wall beta-glucan in the action of HM-1 killer toxin.Q51132649
Cell wall perturbation in yeast results in dual phosphorylation of the Slt2/Mpk1 MAP kinase and in an Slt2-mediated increase in FKS2-lacZ expression, glucanase resistance and thermotolerance.Q54038043
N-glycosylation is involved in the sensitivity of Saccharomyces cerevisiae to HM-1 killer toxin secreted from Hansenula mrakii IFO 0895.Q54102170
Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulationQ57247200
A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C.Q27930780
An osmosensing signal transduction pathway in yeast.Q27932086
The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast.Q27933186
A novel endoplasmic reticulum membrane protein Rcr1 regulates chitin deposition in the cell wall of Saccharomyces cerevisiaeQ27934750
The interaction of Slt2 MAP kinase with Knr4 is necessary for signalling through the cell wall integrity pathway in Saccharomyces cerevisiaeQ27937019
Deletion of HOG1 leads to Osmosensitivity in starvation-induced, but not rapamycin-dependent Atg8 degradation and proteolysis: further evidence for different regulatory mechanisms in yeast autophagyQ27939431
The Rgd1p Rho GTPase-activating protein and the Mid2p cell wall sensor are required at low pH for protein kinase C pathway activation and cell survival in Saccharomyces cerevisiaeQ27940031
Analyzing real-time PCR data by the comparative C(T) methodQ28131831
Biology of killer yeastsQ28218065
Osmotic stress signaling and osmoadaptation in yeastsQ29617597
Cwp2p, the plasma membrane receptor for Pichia membranifaciens killer toxinQ33282903
The glycerol channel Fps1p mediates the uptake of arsenite and antimonite in Saccharomyces cerevisiae.Q34083286
Antifungal drug resistance to azoles and polyenesQ34807486
The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signalingQ35697550
Regulation of the osmoregulatory HOG MAPK cascade in yeastQ35983907
Aquaporins in yeasts and filamentous fungiQ36168506
Effect of calcofluor white on chitin synthases from Saccharomyces cerevisiaeQ36201151
Cloning of the Saccharomyces cerevisiae gene whose overexpression overcomes the effects of HM-1 killer toxin, which inhibits beta-glucan synthesisQ36742815
An electron microscope and electron diffraction study of the effect of calcofluor and congo red on the biosynthesis of chitin in vitroQ36747749
Resistance to echinocandin-class antifungal drugsQ36849595
Yeast osmoregulationQ36944160
Attenuation of echinocandin activity at elevated concentrations: a review of the paradoxical effect.Q36987908
Efflux-mediated antifungal drug resistance.Q37156645
Antifungal resistance mechanisms of AspergillusQ37238725
Antifungal drug resistance mechanisms.Q37463223
Antifungal drug resistance of oral fungiQ37692277
Aspergillus species intrinsically resistant to antifungal agents.Q37775969
Acquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection.Q37783285
The global transcriptional response to transient cell wall damage in Saccharomyces cerevisiae and its regulation by the cell integrity signaling pathwayQ38345649
Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofunginQ39895162
Paradoxical effect of caspofungin: reduced activity against Candida albicans at high drug concentrationsQ39954432
Attenuation of the activity of caspofungin at high concentrations against candida albicans: possible role of cell wall integrity and calcineurin pathways.Q40668367
The PKC, HOG and Ca2+ signalling pathways co-ordinately regulate chitin synthesis in Candida albicans.Q41810708
Changes in cell wall synthesis and ultrastructure during paradoxical growth effect of caspofungin on four different Candida species.Q42111171
A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants.Q42619371
The control of intracellular glycerol in Saccharomyces cerevisiae influences osmotic stress response and resistance to increased temperatureQ42631211
A novel yeast gene, RHK1, is involved in the synthesis of the cell wall receptor for the HM-1 killer toxin that inhibits beta-1,3-glucan synthesisQ42653634
P433issue11
P921main subjectcell wallQ128700
Saccharomyces cerevisiaeQ719725
P304page(s)475-485
P577publication date2012-10-15
P1433published inYeastQ8050997
P1476titleThe high-osmolarity glycerol- and cell wall integrity-MAP kinase pathways of Saccharomyces cerevisiae are involved in adaptation to the action of killer toxin HM-1.
P478volume29

Reverse relations

cites work (P2860)
Q88670096Copper Acyl Salicylate Has Potential as an Anti-Cryptococcus Antifungal Agent
Q37120209Repurposing of Aspirin and Ibuprofen as Candidate Anti-Cryptococcus Drugs
Q37493529The high osmotic response and cell wall integrity pathways cooperate to regulate morphology, microsclerotia development, and virulence in Metarhizium rileyi