Hedgehog inhibition causes complete loss of limb outgrowth and transformation of digit identity in Xenopus tropicalis.

scientific article published on 26 February 2016

Hedgehog inhibition causes complete loss of limb outgrowth and transformation of digit identity in Xenopus tropicalis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JEZ.B.22669
P698PubMed publication ID26918681

P2093author name stringGünter P Wagner
Geffrey F Stopper
Kathryn L Richards-Hrdlicka
P2860cites workCharacterization of two patched receptors for the vertebrate hedgehog protein familyQ22007983
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formationQ24600279
Inhibition of Hedgehog signaling by direct binding of cyclopamine to SmoothenedQ24682703
Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog functionQ28209365
The origin and evolution of animal appendagesQ28237691
Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patchedQ28508563
Some distal limb structures develop in mice lacking Sonic hedgehog signalingQ28587394
Parallel genetic origins of pelvic reduction in vertebratesQ28767855
Sonic hedgehog mediates the polarizing activity of the ZPAQ29616565
Uncoupling Sonic Hedgehog Control of Pattern and Expansion of the Developing Limb BudQ30039622
Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.Q33877368
Phenogenetic drift and the evolution of genotype-phenotype relationshipsQ33927680
Expression of limb initiation genes and clues to the morphological diversification of threespine sticklebackQ34284411
A positive feedback loop coordinates growth and patterning in the vertebrate limb.Q34324097
A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryosQ34346998
Biochemical evidence that patched is the Hedgehog receptorQ34406394
Frame-shifts of digit identity in bird evolution and Cyclopamine-treated wings.Q34604880
Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limbQ36178672
Of chicken wings and frog legs: a smorgasbord of evolutionary variation in mechanisms of tetrapod limb development.Q36295692
A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limbQ36919931
Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structureQ37208723
Interdigital regulation of digit identity and homeotic transformation by modulated BMP signalingQ39542358
The chick oligozeugodactyly (ozd) mutant lacks sonic hedgehog function in the limbQ44254913
Directional asymmetry of pelvic vestiges in threespine sticklebackQ47183762
Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb developmentQ47820096
Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb developmentQ48057670
Inhibition of Sonic hedgehog signaling leads to posterior digit loss in Ambystoma mexicanum: parallels to natural digit reduction in urodeles.Q51717875
Integration of growth and specification in chick wing digit-patterning.Q51961530
Pitx1 and Pitx2 are required for development of hindlimb buds.Q52112246
Ptc1 and Ptc2 transcripts provide distinct readouts of Hedgehog signaling activity during chick embryogenesis.Q52125407
Anterior Duplication of the Sonic hedgehog Expression Pattern in the Pectoral Fin Buds of Zebrafish Treated with Retinoic AcidQ52207450
Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb budQ58198494
P433issue2
P921main subjectWestern clawed frogQ2705052
P304page(s)110-124
P577publication date2016-02-26
P1433published inJournal of Experimental Zoology. Part B: Molecular and Developmental EvolutionQ15760970
P1476titleHedgehog inhibition causes complete loss of limb outgrowth and transformation of digit identity in Xenopus tropicalis.
P478volume326

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cites work (P2860)
Q83229039Fgf-signaling is compartmentalized within the mesenchyme and controls proliferation during salamander limb development
Q39178653Sonic Hedgehog Signaling in Limb Development
Q39043817The origins, scaling and loss of tetrapod digits.

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