Gambogic Acid Induces Cell Apoptosis and Inhibits MAPK Pathway in PTEN-/-/p53-/- Prostate Cancer Cells In Vitro and Ex Vivo

scientific article published on 3 June 2017

Gambogic Acid Induces Cell Apoptosis and Inhibits MAPK Pathway in PTEN-/-/p53-/- Prostate Cancer Cells In Vitro and Ex Vivo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11655-017-2410-3
P698PubMed publication ID28578487

P2093author name stringHong Pan
Kathleen Kelly
Hong-Sheng Lin
Xue-Qian Wang
Bin-Xue Li
Li-Yuan Lu
P2860cites workInnovation: organoids-a better model for prostate cancerQ85356974
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Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cellsQ33982778
c-Fos as a proapoptotic agent in TRAIL-induced apoptosis in prostate cancer cellsQ34139663
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Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosisQ35091267
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A Signaling Network Controlling Androgenic Repression of c-Fos Protein in Prostate Adenocarcinoma CellsQ36674584
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Gambogic acid inhibits TNF-α-induced invasion of human prostate cancer PC3 cells in vitro through PI3K/Akt and NF-κB signaling pathwaysQ37729931
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Gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cellsQ39235972
Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cellsQ39847825
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Gambogic acid potentiates clopidogrel-induced apoptosis and attenuates irinotecan-induced apoptosis through down-regulating human carboxylesterase 1 and -2.Q40124208
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Signal transduction through MAP kinase cascadesQ41750250
Characterizing the Contribution of Stem/Progenitor Cells to Tumorigenesis in thePten−/−TP53−/− Prostate Cancer ModelQ42862750
A preclinical xenograft model of prostate cancer using human tumorsQ43880974
Phenotypic heterogeneity of end-stage prostate carcinoma metastatic to boneQ47744334
PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancerQ47919199
KLF6 and TP53 mutations are a rare event in prostate cancer: distinguishing between Taq polymerase artifacts and true mutations.Q54506769
Prostate cancer in Asia: A collaborative report.Q55216204
Incidental prostate cancer in Asian men: high prevalence of incidental prostatic adenocarcinoma in Chinese patients undergoing radical cystoprostatectomy for treatment of bladder cancer and selection of candidates for prostate-sparing cystectomyQ57641963
Apoptosis during castration-induced regression of the prostate is Fos dependentQ77640377
Anti-inflammatory, analgesic and antipyretic activities of the extract of gamboge from Garcinia hanburyi Hook fQ79948998
Clinical significance of p53 alterations in surgically treated prostate cancersQ81453029
P433issue2
P921main subjectgambogic acidQ105007431
P304page(s)109-116
P577publication date2017-06-03
P1433published inChinese Journal of Integrated Traditional and Western MedicineQ15751116
P1476titleGambogic Acid Induces Cell Apoptosis and Inhibits MAPK Pathway in PTEN-/-/p53-/- Prostate Cancer Cells In Vitro and Ex Vivo
P478volume24

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