Pro-osteogenic topographical cues promote early activation of osteoprogenitor differentiation via enhanced TGFβ, Wnt, and Notch signaling. (scientific article published on 21 April 2013)

Local factor production by MG63 osteoblast-like cells in response to surface roughness and 1,25-(OH)2D3 is mediated via protein kinase C- and protein kinase A-dependent pathways

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Mediation of osteogenic differentiation of human mesenchymal stem cells on titanium surfaces by a Wnt-integrin feedback loop

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Direct and indirect effects of microstructured titanium substrates on the induction of mesenchymal stem cell differentiation towards the osteoblast lineage

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Enhanced human bone marrow stromal cell affinity for modified poly(L-lactide) surfaces by the upregulation of adhesion molecular genes.

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Stem cell-related gene expression in clonal populations of mesenchymal stromal cells from bone marrow

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The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos

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Growth hormone regulates osteogenic marker mRNA expression in human periodontal fibroblasts and alveolar bone-derived cells

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Roughness response genes in osteoblasts

Q44944996

Synergistic interaction of topographic features in the production of bone-like nodules on Ti surfaces by rat osteoblasts

Q45081076

Modified titanium surfaces promote accelerated osteogenic differentiation of mesenchymal stromal cells in vitro

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Development and transplantation of a mineralized matrix formed by osteoblasts in vitro for bone regeneration

Q47893891

Bone apposition around two different sandblasted and acid-etched titanium implant surfaces: a histomorphometric study in canine mandibles

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The microRNA expression signature on modified titanium implant surfaces influences genetic mechanisms leading to osteogenic differentiation.

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Human osteoblast-like cell adhesion on titanium substrates covalently functionalized with synthetic peptides.

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Tissue engineering for bone regeneration using differentiated alveolar bone cells in collagen scaffolds.

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Efficient attenuation of stochasticity in gene expression through post-transcriptional control.

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The influence of surface microroughness and hydrophilicity of titanium on the up-regulation of TGFβ/BMP signalling in osteoblasts

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Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

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NFAT signaling: choreographing the social lives of cells

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Assembly, trafficking and function of gamma-secretase

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Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

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Mice lacking both presenilin genes exhibit early embryonic patterning defects

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NFAT and Osterix cooperatively regulate bone formation

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Enhanced bone apposition to a chemically modified SLA titanium surface

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Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements

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Notch receptor cleavage depends on but is not directly executed by presenilins

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Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling

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Role of non-canonical Wnt signaling in osteoblast maturation on microstructured titanium surfaces.

Q34873239

FGF-2 increases osteogenic and chondrogenic differentiation potentials of human mesenchymal stem cells by inactivation of TGF-beta signaling

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Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility

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The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces.

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Calcium signaling in vertebrate embryonic patterning and morphogenesis

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Dimorphic effects of Notch signaling in bone homeostasis.

Q37165102

Requirement for both micron- and submicron scale structure for synergistic responses of osteoblasts to substrate surface energy and topography

Q37369565

Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation.

Q37906474

Current knowledge about the hydrophilic and nanostructured SLActive surface

Q38106955

Transcriptional profiling of "guided bone regeneration" in a critical-size calvarial defect

Q38335264

Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity

Q38340399

In vivo gene expression profile of guided bone regeneration associated with a microrough titanium surface

Q38502379

Transcriptional profiling of osseointegration in humans

Q38502388

Gene expression profile of osseointegration of a hydrophilic compared with a hydrophobic microrough implant surface

Q38502392

The role of the Wnt/β-catenin pathway in the effect of implant topography on MG63 differentiation.

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The effect of hydrophilic titanium surface modification on macrophage inflammatory cytokine gene expression

Q39441578

P433

issue

P304

page(s)

475-486

P577

publication date

2013-04-21

P1433

published in

Clinical Oral Implants Research

Q15638547

P1476

title

Pro-osteogenic topographical cues promote early activation of osteoprogenitor differentiation via enhanced TGFβ, Wnt, and Notch signaling

P478

volume

Reverse relations

cites work (P2860)

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Q38982705	RhoA controls Wnt upregulation on microstructured titanium surfaces
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Q39356695	The roles of signaling pathways in bone repair and regeneration
Q64927494	miR-381 modulates human bone mesenchymal stromal cells (BMSCs) osteogenesis via suppressing Wnt signaling pathway during atrophic nonunion development.