Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis.

scientific article published on 30 January 2014

Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/HEP.26583
P8608Fatcat IDrelease_noyqhkwqubdrnavivvf5dvgqhe
P932PMC publication ID6377365
P698PubMed publication ID23787765
P5875ResearchGate publication ID240309177

P50authorBeth HolderQ56433912
P2093author name stringGiorgina Mieli-Vergani
Yun Ma
Simon C Robson
John Cardone
Diego Vergani
Maria Serena Longhi
Rodrigo Liberal
Charlotte R Grant
P2860cites workImpairment of CD4(+)CD25(+) regulatory T-cells in autoimmune liver disease.Q47219414
Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis.Q51244795
Autoimmune hepatitis in childhood: a 20-year experience.Q53361457
Autoantigen-specific regulatory T cells, a potential tool for immune-tolerance reconstitution in type-2 autoimmune hepatitisQ83316443
IL-17 contributes to autoimmune hepatitisQ84749635
How regulatory T cells workQ29614262
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppressionQ29615344
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cellsQ29618394
Interleukin-17 contributes to the pathogenesis of autoimmune hepatitis through inducing hepatic interleukin-6 expressionQ33883569
Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitisQ34090541
CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in miceQ34091467
Expression of CD39 on FoxP3+ T regulatory cells correlates with progression of HBV infection.Q34226860
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosineQ34578972
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.Q34621389
T-cell specific defect in expression of the NTPDase CD39 as a biomarker for lupusQ35199844
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cellsQ36228688
CD73 is a phenotypic marker of effector memory Th17 cells in inflammatory bowel diseaseQ36566752
From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel diseaseQ37377260
Aetiopathogenesis of autoimmune hepatitisQ37600271
Expression of CD39 by human peripheral blood CD4+ CD25+ T cells denotes a regulatory memory phenotype.Q41985015
CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosisQ43241046
A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitisQ44739483
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1007-1015
P577publication date2014-01-30
P1433published inHepatologyQ15724398
P1476titleDysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis
P478volume59

Reverse relations

cites work (P2860)
Q41660660"Autoimmune(-Like)" Drug and Herb Induced Liver Injury: New Insights into Molecular Pathogenesis
Q35694206A novel "humanized mouse" model for autoimmune hepatitis and the association of gut microbiota with liver inflammation.
Q26753195Adaptive immunity in the liver
Q38358000Adenosine signalling in diabetes mellitus--pathophysiology and therapeutic considerations
Q39035161Adoptive cell transfer in autoimmune hepatitis
Q91654961Alopecia areata patients show deficiency of FOXP3+CD39+ T regulatory cells and clonotypic restriction of Treg TCRβ-chain, which highlights the immunopathological aspect of the disease
Q35906055Autoimmune Hepatitis: Clinical Review with Insights into the Purinergic Mechanism of Disease
Q59349440Autoimmune hepatitis
Q86886381Autoimmune hepatitis
Q42365127Autoimmune hepatitis: 50 Years of (slow) progress
Q38692080Autoimmune hepatitis: From current knowledge and clinical practice to future research agenda.
Q38494826Autoimmune hepatitis: an approach to disease understanding and management
Q34550808Autoimmune hepatitis: current challenges and future prospects
Q42289803Bilirubin suppresses Th17 immunity in colitis by upregulating CD39.
Q35202450CD39 deficiency in murine liver allografts promotes inflammatory injury and immune-mediated rejection
Q52868007CD39 mediated regulation of Th17-cell effector function is impaired in juvenile autoimmune liver disease.
Q51050332CD39+ regulatory T cells attenuate allergic airway inflammation.
Q38285331Cell mediators of autoimmune hepatitis and their therapeutic implications
Q35088318Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease
Q36977772Current and potential immune therapies and vaccines in the management of psoriasis
Q48264506Distinct roles of ecto-nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) in liver regeneration and fibrosis.
Q64274419Dysregulation of Adenosinergic Signaling in Systemic and Organ-Specific Autoimmunity
Q55475388Ectonucleotidase-Mediated Suppression of Lupus Autoimmunity and Vascular Dysfunction.
Q64075135Ectonucleotidases in Intestinal and Hepatic Inflammation
Q34201736Efficacy and safety of immunosuppressive therapy in the treatment of seronegative hepatitis associated aplastic anemia
Q102152125Endogenous antisense RNA curbs CD39 expression in Crohn's disease
Q38730872Evolving paradigm of treatment for autoimmune hepatitis
Q90005422Fas, FasL and Foxp3 gene expression in post-liver transplant autoimmune hepatitis patients with and without acute rejection
Q34624054Gut microbiome and the risk factors in central nervous system autoimmunity.
Q56967377HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease
Q38238921Hepatitis mouse models: from acute-to-chronic autoimmune hepatitis
Q42108248Human intrahepatic regulatory T cells are functional, require IL-2 from effector cells for survival, and are susceptible to Fas ligand-mediated apoptosis
Q58799838Immune Alterations in Patients With Type 1 Autoimmune Hepatitis Persist Upon Standard Immunosuppressive Treatment
Q42369863Immunity and Fibrogenesis: The Role of Th17/IL-17 Axis in HBV and HCV-induced Chronic Hepatitis and Progression to Cirrhosis.
Q38930837Immunosuppressive drugs affect interferon (IFN)-γ and programmed cell death 1 (PD-1) kinetics in patients with newly diagnosed autoimmune hepatitis.
Q52945081In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression.
Q91950939Inhibition of the adenosinergic pathway: the indispensable part of oncological therapy in the future
Q52561169Interleukin 2 promotes hepatic regulatory T cell responses and protects from biliary fibrosis in murine sclerosing cholangitis.
Q47790004Involvement of the Nrf2/HO-1/CO axis and therapeutic intervention with the CO-releasing molecule CORM-A1, in a murine model of autoimmune hepatitis.
Q52564630NOD-Like Receptor Protein 3 Inflammasome-Dependent IL-1β Accelerated ConA-Induced Hepatitis.
Q90734771Novel Diagnostic and Therapeutic Strategies in Juvenile Autoimmune Hepatitis
Q37607111Novel Immunotherapies for Autoimmune Hepatitis.
Q33898237Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy
Q58130515Phenotypic alterations of regulatory T cells in autoimmune hepatitis: causal or associated with treatment and remission?
Q38230723Purinergic signaling in liver disease.
Q37706119Rapamycin regulates iTreg function through CD39 and Runx1 pathways
Q35725777Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis
Q26827787Regulatory T cells: Mechanisms of suppression and impairment in autoimmune liver disease
Q52766142Regulatory T-cell conditioning endows activated effector T cells with suppressor function in autoimmune hepatitis/autoimmune sclerosing cholangitis.
Q87416598Reply: To PMID 23787765
Q27025680Review article: chemokines as orchestrators of autoimmune hepatitis and potential therapeutic targets
Q38799687Surface Antigen Profiling of Helicobacter pylori-Infected and -Uninfected Gastric Cancer Cells Using Antibody Microarray.
Q39228029Th17 Responses to Collagen Type V, kα1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout Life
Q64968998The Imbalance between Foxp3+Tregs and Th1/Th17/Th22 Cells in Patients with Newly Diagnosed Autoimmune Hepatitis.
Q56378345The Role of Invariant NKT in Autoimmune Liver Disease: Can Vitamin D Act as an Immunomodulator?
Q35849575The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis
Q39161005The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets
Q49036478The induction of autoimmune hepatitis in the human leucocyte antigen-DR4 non-obese diabetic mice autoimmune hepatitis mouse model.
Q38926183The influence of gut-derived CD39 regulatory T cells in CNS demyelinating disease
Q28069199The role of adenosinergic pathway in human autoimmune diseases
Q38543052Therapeutic Potential of IL-17-Mediated Signaling Pathway in Autoimmune Liver Diseases

Search more.