| scholarly article | Q13442814 |
| P50 | author | Stanley J. Korsmeyer | Q138795 |
| P2093 | author name string | Donna S Neuberg | |
| Scott A Armstrong | |||
| A Thomas Look | |||
| Lewis B Silverman | |||
| Stephen E Sallan | |||
| Adolfo A Ferrando | |||
| P2860 | cites work | Commitment to the B-lymphoid lineage depends on the transcription factor Pax5 | Q22010683 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | leukemia | Q29496 |
| P304 | page(s) | 262-268 | |
| P577 | publication date | 2003-03-13 | |
| P1433 | published in | Blood | Q885070 |
| P1476 | title | Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation. | |
| P478 | volume | 102 |
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| Q37023597 | Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia |
| Q56722375 | Acute lymphoblastic leukaemia |
| Q58481753 | Acute lymphoblastic leukaemia |
| Q46976753 | Acute monocytic leukemia with coexpression of minor BCR-ABL1 and PICALM-MLLT10 fusion genes along with overexpression of HOXA9. |
| Q37031831 | An MLL-dependent network sustains hematopoiesis. |
| Q42216959 | Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction |
| Q28210411 | B-cell development in the presence of the MLL/AF4 oncoprotein proceeds in the absence of HOX A7 and HOX A9 expression |
| Q54648219 | CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes. |
| Q36056038 | CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements. |
| Q46424987 | Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage |
| Q36436582 | Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells |
| Q40559637 | Childhood T-Cell Acute Lymphoblastic Leukemia: The Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium Experience |
| Q33666543 | Chromatin modifications as therapeutic targets in MLL-rearranged leukemia |
| Q36511855 | Chromatin remodeling in cancer: a gateway to regulate gene transcription |
| Q30835184 | Classifying leukemia types with chromatin conformation data |
| Q47293487 | Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRbeta-HOXA rearrangement: a study of the Groupe Francophone de Cytogénétique Hématologique. |
| Q40524531 | Clustering of gene hypermethylation associated with clinical risk groups in neuroblastoma |
| Q33587655 | Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults |
| Q37078747 | Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias |
| Q24646924 | Constitutively active SHP2 cooperates with HoxA10 overexpression to induce acute myeloid leukemia |
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| Q36529795 | Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast |
| Q51360345 | DNA methylation profiling of pediatric B-cell lymphoblastic leukemia with KMT2A rearrangement identifies hypomethylation at enhancer sites. |
| Q36007351 | DNA microarrays in the diagnosis and management of acute lymphoblastic leukemia |
| Q28539096 | DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy |
| Q92856196 | Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia |
| Q34170361 | Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivo |
| Q56518873 | Dysregulated transcriptional networks in and -rearranged T-ALL |
| Q24627258 | Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia |
| Q36219661 | Emerging drugs for adult acute lymphoblastic leukaemia |
| Q45754556 | Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia |
| Q38459868 | Epigenetic modifiers in normal and malignant hematopoiesis |
| Q93027164 | Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia |
| Q28077082 | Epigenetics in Cancer: A Hematological Perspective |
| Q38289023 | Epigenetics in T-cell acute lymphoblastic leukemia |
| Q81740968 | Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia |
| Q28507053 | Evidence that the Pim1 kinase gene is a direct target of HOXA9 |
| Q24685883 | Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols |
| Q46569720 | FLT3 inhibition in t(4;11)+ adult acute lymphoid leukaemia |
| Q93111981 | Functional diversity of inhibitors tackling the differentiation blockage of MLL-rearranged leukemia |
| Q35569558 | Gene expression profiling in T-cell acute lymphoblastic leukemia |
| Q35619779 | Gene expression profiling in childhood acute leukemia: progress and perspectives |
| Q36050530 | Gene expression profiling using RNA extracted from whole blood: technologies and clinical applications |
| Q35573313 | Gene expression profiling: will it complement or replace immunophenotyping? |
| Q24621301 | Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia |
| Q33478506 | Genetic rearrangement MLL/AF4 is most frequent in children with acute lymphoblastic leukemias in Mexico City. |
| Q38223490 | Genomic characterization of acute leukemias |
| Q37810126 | Genomic polymorphisms in sickle cell disease: implications for clinical diversity and treatment |
| Q36589152 | Genomic profiling in clinical oncology. The predictive value of genomic information in cancer management |
| Q53325167 | Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells? |
| Q34578326 | HOX deregulation in acute myeloid leukemia |
| Q81807188 | HOX genes: not just myeloid oncogenes any more |
| Q40797140 | HOX proteins and leukemia. |
| Q42397478 | HOXA-activated early T-cell progenitor acute lymphoblastic leukemia: predictor of poor outcome? |
| Q37129652 | HOXA9 is required for survival in human MLL-rearranged acute leukemias |
| Q58492940 | High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome |
| Q49481866 | Homeobox C10 knockdown suppresses cell proliferation and promotes cell apoptosis in osteosarcoma cells through regulating caspase 3. |
| Q34700749 | Hox genes in hematopoiesis and leukemogenesis. |
| Q42770287 | HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia |
| Q46178511 | Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression |
| Q24610737 | Identification and characterization of Hoxa9 binding sites in hematopoietic cells |
| Q35989408 | Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group |
| Q54558913 | Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement. |
| Q33788690 | Inactivation of LEF1 in T-cell acute lymphoblastic leukemia |
| Q42369126 | Integrative Analysis of Transcription Factor Combinatorial Interactions Using a Bayesian Tensor Factorization Approach |
| Q37032161 | Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia |
| Q37832457 | Key roles of histone methyltransferase and demethylase in leukemogenesis. |
| Q38288626 | Loss of MLL PHD finger 3 is necessary for MLL-ENL-induced hematopoietic stem cell immortalization |
| Q37738416 | Lymphoblastic lymphoma in adults |
| Q24680998 | MCEF is localized to the nucleus by protein sequences encoded within three distinct exons, where it represses HIV-1 Tat-transactivation of LTR-directed transcription |
| Q35788362 | MLL fusions: pathways to leukemia |
| Q30440771 | MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression. |
| Q30277191 | MLL rearrangements impact outcome in HOXA-deregulated T-lineage acute lymphoblastic leukemia: a Children's Oncology Group Study |
| Q35569555 | MLL-rearranged leukemias: insights from gene expression profiling |
| Q38190545 | Mechanisms of mixed-lineage leukemia |
| Q36970219 | Mechanisms of transcription factor deregulation in lymphoid cell transformation |
| Q36098242 | Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential. |
| Q36602853 | MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies |
| Q28471927 | Misguided transcriptional elongation causes mixed lineage leukemia |
| Q28247462 | Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein |
| Q38161393 | Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis |
| Q36585592 | Molecular biology in acute leukemia |
| Q36153422 | Molecular genetic analysis of haematological malignancies: I. Acute leukaemias and myeloproliferative disorders |
| Q37802059 | Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia |
| Q36232545 | Molecular pathogenesis of MLL-associated leukemias |
| Q36663495 | Myeloid ecotropic viral integration site 1 (MEIS) 1 involvement in embryonic implantation |
| Q38239669 | NUP214 fusion genes in acute leukemia (Review). |
| Q35608150 | NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights |
| Q33601322 | NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function. |
| Q24336625 | New insight into the molecular mechanisms of MLL-associated leukemia |
| Q35067391 | New markers for minimal residual disease detection in acute lymphoblastic leukemia |
| Q36448329 | Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia |
| Q39357822 | Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency |
| Q35538663 | Novel Cryptic Rearrangements in Adult B-Cell Precursor Acute Lymphoblastic Leukemia Involving the MLL Gene |
| Q37738484 | Novel insights into the development of T-cell acute lymphoblastic leukemia. |
| Q37719992 | Overexpression of SLC25A38 protein on acute lymphoblastic leukemia cells |
| Q37426858 | PHF6 mutations in adult acute myeloid leukemia |
| Q37970679 | Pathogenetic, Clinical, and Prognostic Features of Adult t(4;11)(q21;q23)/MLL-AF4 Positive B-Cell Acute Lymphoblastic Leukemia |
| Q92151828 | Pathways, Processes, and Candidate Drugs Associated with a Hoxa Cluster-Dependency Model of Leukemia |
| Q57734345 | Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias |
| Q33951701 | Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines |
| Q35750140 | Postgenomic global analysis of translational control induced by oncogenic signaling |
| Q38324390 | Prospective gene expression analysis accurately subtypes acute leukaemia in children and establishes a commonality between hyperdiploidy and t(12;21) in acute lymphoblastic leukaemia |
| Q34430521 | Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins. |
| Q47429067 | Receptor kinase profiles identify a rationale for multitarget kinase inhibition in immature T-ALL. |
| Q24646499 | Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization |
| Q33716402 | Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor. |
| Q33868208 | Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in individual and meta-analysis studies. |
| Q91564481 | Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia |
| Q83269863 | T-cell acute lymphoblastic leukemia |
| Q42182795 | TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia |
| Q35967446 | Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond |
| Q37722452 | The Hox genes and their roles in oncogenesis. |
| Q38349193 | The Oncogene Nup98-HOXA9 Induces Gene Transcription in Myeloid Cells |
| Q38053050 | The dual roles of homeobox genes in vascularization and wound healing |
| Q81691719 | The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin |
| Q42741956 | The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia |
| Q38906841 | The genetics and mechanisms of T cell acute lymphoblastic leukaemia |
| Q37874929 | The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia |
| Q40202913 | The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling |
| Q38047834 | The molecular basis of T cell acute lymphoblastic leukemia |
| Q37522825 | The molecular biology of mixed lineage leukemia |
| Q37730254 | The molecular signature of oncofusion proteins in acute myeloid leukemia. |
| Q36052947 | The pathogenesis of mixed-lineage leukemia |
| Q36591345 | The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia |
| Q38065068 | The role of HOX genes in normal hematopoiesis and acute leukemia. |
| Q34287512 | The role of the MLL gene in infant leukemia |
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| Q37234595 | Therapeutic targeting of MLL. |
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| Q36239212 | When epigenetics kills: MLL fusion proteins in leukemia |
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