CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations.

scientific article published on 3 March 2017

CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations. is …
instance of (P31):
case reportQ2782326
scholarly articleQ13442814

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P356DOI10.1210/JC.2016-4048
P932PMC publication ID5443336
P698PubMed publication ID28324001

P50authorHakon HakonarsonQ30003940
P2093author name stringDong Li
Kenneth E Thummel
Michael A Levine
Kevin E Meyers
Colin Patrick Hawkes
P2860cites workIdiopathic hypercalcaemia in infantsQ73208515
Idiopathic hypercalcaemia in infants with failure to thriveQ73537397
Impact of genetic polymorphism in relation to other factors on expression and function of human drug-metabolizing p450sQ82289060
Ketoconazole in Cushing's disease: is it worth a try?Q87179331
Genetic defect in CYP24A1, the vitamin D 24-hydroxylase gene, in a patient with severe infantile hypercalcemiaQ24634055
An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathwayQ30511948
An official ATS statement: hepatotoxicity of antituberculosis therapyQ34571651
The effect of multiple-dose, oral rifaximin on the pharmacokinetics of intravenous and oral midazolam in healthy volunteersQ34583322
Simultaneous measurement of plasma vitamin D(3) metabolites, including 4β,25-dihydroxyvitamin D(3), using liquid chromatography-tandem mass spectrometryQ35189519
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytesQ35608569
Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapyQ35869662
Enhancement of hepatic 4-hydroxylation of 25-hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: implications for drug-induced osteomalaciaQ36721536
1,25-(OH)2D-24 Hydroxylase (CYP24A1) Deficiency as a Cause of NephrolithiasisQ36733570
Association of Mutations in SLC12A1 Encoding the NKCC2 Cotransporter With Neonatal Primary Hyperparathyroidism.Q36911479
Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.Q37160635
Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalaciaQ38320243
Bioengineering anabolic vitamin D-25-hydroxylase activity into the human vitamin D catabolic enzyme, cytochrome P450 CYP24A1, by a V391L mutationQ38672766
A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosisQ41475312
Successful treatment of hypercalcaemia associated with a CYP24A1 mutation with fluconazole.Q42392666
Osteomalacia in an HIV-infected man receiving rifabutin, a cytochrome P450 enzyme inducer: a case reportQ43058205
Infantile hypercalcemia and hypercalciuria: new insights into a vitamin D-dependent mechanism and response to ketoconazole treatment.Q43098170
Mutations in CYP24A1 and idiopathic infantile hypercalcemiaQ45345347
Hepatotoxicity associated with antifungal therapy after bone marrow transplantationQ46593130
Effect of antifungal drugs on cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 activities in human liver microsomesQ46686355
Mutational Spectrum of CYP24A1 Gene in a Cohort of Italian Patients with Idiopathic Infantile Hypercalcemia.Q54149900
Rifampin preventive therapy for tuberculosis infection: experience with 157 adolescentsQ64133863
Use of ketoconazole to probe the pathogenetic importance of 1,25-dihydroxyvitamin D in absorptive hypercalciuriaQ67602886
Rifampicin-induced adrenal crisis in addisonian patients receiving corticosteroid replacement therapyQ70648914
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectvitamin DQ175621
rifampicinQ422652
P304page(s)1440-1446
P577publication date2017-05-01
P1433published inThe Journal of Clinical Endocrinology and MetabolismQ3186902
P1476titleCYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations.
P478volume102

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cites work (P2860)
Q87828161CYP3A4 mutation causes vitamin D-dependent rickets type 3
Q90374323Consensus statement from 2nd International Conference on Controversies in Vitamin D
Q57174194Drug-metabolizing enzymes CYP3A as a link between tacrolimus and vitamin D in renal transplant recipients: is it relevant in clinical practice?
Q64066212Hereditary Hypercalcemia Caused by a Homozygous Pathogenic Variant in the Gene: A Case Report and Review of the Literature
Q92630903Nephrocalcinosis: A Review of Monogenic Causes and Insights They Provide into This Heterogeneous Condition
Q55030066Nephrolithiasis and Nephrocalcinosis in Childhood-Risk Factor-Related Current and Future Treatment Options.
Q64940667Three Sisters With Heterozygous Gene Variants of CYP24A1: Maternal Hypercalcemia, New-Onset Hypertension, and Neonatal Hypoglycemia.
Q57191698Vitamin D Toxicity-A Clinical Perspective

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