Human pharmacokinetics and tolerability of L-365,260, a novel cholecystokinin-B antagonist.

scientific article published in April 1996

Human pharmacokinetics and tolerability of L-365,260, a novel cholecystokinin-B antagonist. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/J.1552-4604.1996.TB04204.X
P698PubMed publication ID8728342

P50authorOwen M. WolkowitzQ59678011
P2093author name stringJ Zhang
J Lin
L Clarke
J R Seibold
H Weingartner
M G Murphy
K Grasing
K Putnam
D Freedholm
M Swigar
P2860cites workThe selective CCK-B receptor antagonist L-365,260 enhances morphine analgesia and prevents morphine tolerance in the ratQ28278422
Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activityQ28334293
Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the ratQ29619517
PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analgesic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive reflexesQ33792380
Cholecystokinin-tetrapeptide induces panic attacks in patients with panic disorderQ34205234
CI988, a selective antagonist of cholecystokininB receptors, prevents morphine tolerance in the ratQ34466681
Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK.Q35815910
Functional role of brain CCK receptorsQ37278765
Evidence for an involvement of the brain cholecystokinin B receptor in anxietyQ37395948
The role of CCK caerulein, and CCK antagonists in nociceptionQ38759937
Release of cholecystokinin in the central nervous systemQ40918018
The panicogenic effects of cholecystokinin-tetrapeptide are antagonized by L-365,260, a central cholecystokinin receptor antagonist, in patients with panic disorderQ41030900
The gastrin-receptor antagonist L-365,260 inhibits stimulated acid secretion in humansQ43786284
Hunger in humans induced by MK-329, a specific peripheral-type cholecystokinin receptor antagonist.Q45977303
Benzodiazepines antagonize cholecystokinin-induced activation of rat hippocampal neuronesQ46452290
Brain CCK receptors are structurally distinct from pancreas CCK receptorsQ48611898
Cholecystokinin tetrapeptide induces panic-like attacks in healthy volunteers. Preliminary findings.Q51176483
LAGRAN program for area and moments in pharmacokinetic analysis.Q51659721
Estimation of variance for harmonic mean half-lives.Q52676346
An analysis of variance test for normality (complete samples)Q57253423
P433issue4
P921main subjectpharmacokineticsQ323936
cholecystokininQ60315441
P304page(s)292-300
P577publication date1996-04-01
P1433published inThe Journal of Clinical PharmacologyQ7743562
P1476titleHuman pharmacokinetics and tolerability of L-365,260, a novel cholecystokinin-B antagonist.
P478volume36

Reverse relations

cites work (P2860)
Q47737537Cholecystokinin and psychiatric disorders : role in aetiology and potential of receptor antagonists in therapy
Q51877974Effect of intranasally administered cholecystokinin on encoding of controlled and automatic memory processes.